EFFECT OF DOXORUBICIN THERAPY ON TRANSMISSIBLE VENEREAL TUMOUR IN DOGS
Keywords:
Transmissible venereal tumour, Doxorubicin, Vincristine, Chemotherapy, DogsAbstract
The efficacy and toxicity of doxorubicin therapy on transmissible venereal tumors in dogs in comparison with
vincristine was studied. Vincristine at the dose rate of 0.025 mg/kg intravenously resulted in complete remission
of tumour in five of six cases giving 83.33 per cent success rate while Doxorubicin at a dose rate of 30 mg/m2
intravenously caused complete remission of tumour mass in five of the six cases (83.33) and partial remission in
one. The side effects such as anorexia, vomiting commonly seen with vincristine administration was minimal with
doxorubici n hydrochloride.