EFFECT OF LEAD ACETATE ON SPERM MORPHOLOGY AND TESTIS OF WISTAR ALBINO RATS

Authors

  • K SUJATHA Department of Pathology, College of Veterinary Science, Sri Venkateswara Veterinary University, Tirupati-517 502, Andhra Pradesh, INDIA
  • C H SRILATHA Department of Pathology, College of Veterinary Science, Sri Venkateswara Veterinary University, Tirupati-517 502, Andhra Pradesh, /INDIA
  • Y ANJANEYULU
  • T S CHANDRASEKHAR RAO Department of Pathology, College of Veterinary Science, Sri Venkateswara Veterinary University, Tirupati-517 502, Andhra Pradesh, INDIA
  • D SREENIVASULU Department of Pathology, College of Veterinary Science, Sri Venkateswara Veterinary University, Tirupati-517 502, Andhra Pradesh, INDIA
  • P AMARAVATHI

Keywords:

Lead poisoning, Testis, Sperm morphology, Histopathology, Histochemistry, Albino rats

Abstract

In the present study different doses of lead acetate was used to know the effect on testis, sperm count,
sperm morphology in different experimental groups. 108 male wistar rats were divided into three equal groups (I, II
&111) i.e. each group contains 36 rats. Group I kept as control. Group II & Ill rats were orally administered lead
acetate@ 60 mgs & 30mgs /kg. bwt / 3 days in a week for 90 days. Every fortnight from each group rats were
sacrificed with anesthetic ether and epididymis collected for sperm count, testes for measurement of testicular
weight and pieces of testis fixed in Bevin's fixative for histopathological and histochemical studies. The study
revealed that lead acetate caused a dose dependant reduction in sperm count, testicular weight, and abnormal
sperm count was increased significantly when compared to control. Hisopathologically testis shows necrosis of
seminiferous tubules. Complete separation and disappearance of seminiferous tubular epithelium. Lead also caused
reduction in testicular alkaline phosphatase activity.

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Published

2011-12-31

Issue

Vol. 32 No. 2 (2011): Indian Journal of Animal Reproduction

Section

Research Article

How to Cite

SUJATHA, K., SRILATHA, C.H., ANJANEYULU, Y., RAO, T.S.C., SREENIVASULU, D., & AMARAVATHI, P. (2011). EFFECT OF LEAD ACETATE ON SPERM MORPHOLOGY AND TESTIS OF WISTAR ALBINO RATS. The Indian Journal of Animal Reproduction, 32(2), 63–67. Retrieved from https://acspublisher.com/journals/index.php/ijar/article/view/4676