SERUM TRI-IODOTHYRONINE AND THYROXINE PROFILE IN INSULIN TREATED ACYCLIC GOATS

Abstract

The present work was carried out with the objective of estimating of tri-iodothyronine (T3) and thyroxine (T 4)
concentrations in insulin treated acyclic goats. Fourteen acyclic goats were randomly divided into two groups, i.e.
groupA(control, n::: 7) and group B (insulin treated, n::: 7).Animals of treatment group were injected subcutaneously
with long acting bovine insulin at 0.2 IU/kg bodyweight, once daily for five consecutive days. All the experimental
goats were subjected to collection of blood on day O (day of first injection), 4, 8, 12, 16, 20, 24 and day 28.
Estimation of T3 and T 4 were carried out by using RIA. The mean values of T3 were significantly higher or on day
4, 28 (P < 0.01), 12, 16, 20 and 24 (P<0.05) in treated goats as compared to control. However, the T4 levels in
treatment group were significantly higher (P<0.05 or P < 0.01) on days 4, 8, 12, 16 and 20.