THERAPEUTIC EFFICACY OF MIFEPRISTONE, CABERGOLINE AND CLOPROSTENOL FOR TERMINATION OF PREGNANCY IN BITCHES

Abstract

A total of 24 cases of misalliance in bitches were utilized to study the efficacy of various therapeutic protocols
for termination of pregnancy after early confirmation of pregnancy. These bitches were randomly allotted to three
treatment and one control group with 6 bitches in each group. Pregnancy was terminated 100 per cent in all the
three treatment groups. The incidence of abortion and resorption in -mifepristone treated group was 15.38 and
84.62, in cabergoline plus cloprostenol group was O and 100, in cloprostenol group was 26.09 and 73.91 and in
control group was O and 6.66 per cent respectively. Treatment groups had significantly shorter inter estrous cycle
interval than control group. The average number of pups born in the next whelping was 3. 5 ± 0.22, 5.67 ± 0 .33, 3.34
± 0.55 and 5.0 ± 0.58 in mifepristone, cabergoline plus cloprostenol, cloprostenol and control groups respectively.
These three treatment protocols can be effectively used for the termination of pregnancy in bitches.