EARLY EMBRYONIC DEATH ASSOCIATED CHANGES IN STEROID HORMONES, LEPTIN, IGF-1, NITRIC OXIDE, ZINC AND COPPER IN MARES

Authors

  • ASHA MOHAMMAD Department of Theriogenology, Faculty of Veterinary Medicine, Benha University, Egypt
  • MMM KANDIEL
  • MEA ABOU-EL-ROOS
  • AI EL AZAB
  • AM ABO EL-MAATY

Keywords:

Early embryonic death, IGF-1, Mare, Nitric oxide, Leptin

Abstract

Mares exhibting early embryonic death (EED, n=8), non-pregnancy (NP, n=12) and pregnancy (P, n=10) underwent ultrasound examination and blood sampling until week 4 post-breeding to assess the changes in reproductive and metabolic hormones, nitric oxide (NO), copper and zinc. Progesterone increased (p<0.05) and NO decreased (p<0.05) in P mares compared to EED and NP mares. Zinc (p≤0.05) at week 1, copper (p≤0.05) at week 2, and NO and copper (p<0.05), and estradiol and leptin (p≤0.05) at week 4 varied between NP, P and EED mares. The disturbance in ovarian and metabolic hormones concomitant with inflammatory mediators and/ or trace-elements might be responsible for EED in mares.

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Published

2022-12-31

Issue

Vol. 39 No. 2 (2018): Indian Journal of Animal Reproduction

Section

Research Article

How to Cite

MOHAMMAD, A., KANDIEL, M., ABOU-EL-ROOS, M., EL AZAB, A., & ABO EL-MAATY, A. (2022). EARLY EMBRYONIC DEATH ASSOCIATED CHANGES IN STEROID HORMONES, LEPTIN, IGF-1, NITRIC OXIDE, ZINC AND COPPER IN MARES . The Indian Journal of Animal Reproduction, 39(2), 9–14. Retrieved from https://acspublisher.com/journals/index.php/ijar/article/view/3836