CURRENT TRENDS IN HUMAN DENTAL TELOMERE LENGTH MEASUREMENTS IN FORENSIC AGE ESTIMATION – A NARRATIVE REVIEW
Keywords:
Telomere, Tooth, DNA, methods, age estimation, forensicsAbstract
Tooth, due to the anatomical framework of hard minerals, is a reliable source in forensic identification, sex determination, and age estimation. Although Morphological, radiological, and histological methods are effective methods, the advancements in molecular methods have shifted the focus of research towards changes occurring in DNA to age and sex. Molecular methods are useful when other methods fail to estimate the age. Telomere length attrition and DNA methylation are the two extensively studied areas in dental forensic age estimation. This review attempts to narrate the current
References
Callicott RJ., and James EW. Real-Time PCR Assay for Measurement of Mouse Telomeres. Comparative Medicine. 2006;56(1):17–22.
Chu R. Age and Sex-Related Differences in Dental Pulp Stem Cells. ProQuest Dissertations and Theses. 2013; 68.
Girish KL, Farzan SR, and Shoaib RT. Dental DNA Fingerprinting in Identification of Human Remains. Journal of Forensic Dental Sciences. 2010; 2(2):63.
Higgins D, Kaidonis J, Townsend G, Hughes T, Austin JJ. Targeted sampling of cementum for recovery of nuclear DNA from human teeth and the impact of common decontamination measures. Investig Genet. 2013;4(1):1–8.
Inostroza C, Carrasco P, Godoy M, Gatti G, Paulino B. Dental Forensic Kit (DFK®) and Quick ExtractTM FFPE DNA extraction kit, a new workflow for obtaining dental DNA for human genetic identity. J Forensic Leg Med. 2020;73(May).:1-7
Jeon BG, Kang EJ, Mohana Kumar B, Maeng GH, Ock SA, Kwack DO, Park BW, Rho GJ. Comparative analysis of telomere length, telomerase and reverse transcriptase activity in human dental stem cells. Cell Transplant. 2011;20(11–12):1693–705.
Korleviæ P, Gerber T, Gansauge MT, Hajdinjak M, Nagel S, Aximu-Petri A, Mayer M. Reducing microbial and human contamination in dna extractions from ancient bones and teeth. Biotechniques. 2015;59(2):87– 93.
Kumei Y, Akiyama H, Onizuka T, Kobayashi C. Variation of telomeric DNA content in gingiva and dental pulp. Arch Oral Biol [Internet]. 2011;56(12):1641– 5.
Malaver PC, Yunis JJ. Different dental tissues as source of DNA for human identification in forensic cases. Croat Med J. 2003;44(3):306–9.
Márquez-Ruiz AB, González-Herrera L, Valenzuela A. Usefulness of telomere length in DNA from human teeth for age estimation. Int J Legal Med. 2018;132(2):353–9.
Mokry J, Soukup T, Micuda S, Karbanova J, Visek B, Brcakova E, Suchanek J, Bouchal J, Vokurkova D, Ivancakova R. Telomere attrition occurs during ex vivo expansion of human dental pulp stem cells. J Biomed Biotechnol. 2010;2010:1-11
Naafs M. Dental DNA Finger printing. Mod Approaches Dent Oral Heal Care. 2018;2(4):189–93.
Pfeiffer H, Huhne J, Seitz B, Brinkmann B. Influence of soil storage and exposure period on DNA recovery from teeth. Int J Legal Med. 1999;112(2):142–4.
Potsch L, Meyer U, Rothschild S, Schneider PM, Rittner Ch. Application of DNA techniques for identification using human dental pulp as a source of DNA*. 1992;105:139–43.
Rhonan FS , Sávio DP , Eduardo DJ, Rejane da Silva SB, Neide MG RS. Genetics and molecular biology: a literature review of forensic dentistry application. Brazilian J Oral Sci. 2007;6(20):1254–9.
Rubio L, Santos I, Gaitan MJ, Martin De- Las Heras S. Time-dependent changes in DNA stability in decomposing teeth over 18 months. Acta Odontol Scand. 2013;71(3–4):638–43.
Saravanakumar V, Santhadevy A, Satish KG, Nagaraj V. Extraction of DNA From Odontoblastic Process of Permanent Tooth Dentin- A Pilot Study. 2015;2(2):210–3.
Smith BC, Fisher DL, Weedn VW, Warnock GR, Holland MM. A Systematic Approach to the Sampling of Dental DNA. J Forensic Sci. 1993;38(5):1194-1209
Takasaki T, Tsuji A, Ikeda N, Ohishi M. Age estimation in dental pulp DNA based on human telomere shortening. Int J Legal Med. 2003;117(4):232–4.
Trivedi R, Chattopadhyay P, Kashyap VK. A new improved method for extraction of DNA from teeth for the analysis of hypervariable loci. Am J Forensic Med Pathol. 2002;23(2):191–6.
