MICROBIAL PROFILE OF INFECTIONS IN BURN PATIENTS
Keywords:
Female Burn, Infection, MicroorganismAbstract
As per the data of Union health ministry of India, our country records 70 lakh burn injury cases annually of which 1.5 lakh people die every year. Burn patients have unique predisposition to different infections which are linked to impaired resistance from disruption of the skin’s mechanical integrity and generalized immune suppression. Infection causes 50% to 60% of deaths in burn patients in spite of intensive therapy with antibiotics both topically as well as intravenous. Sixty female burns victim were analyzed to make the microbial profile in burn patients from the surface wound and from internal organ (spleen). In burn surface wounds predominant organism was Pseudomonas followed by Klebsiella, Citrobacter. In the splenic tissue most common isolated organism was Klebsiella followed by Citrobacter and Pseudomonas. Proteus vulgaris was isolated only in spleenic tissue.
References
1. Ministry of Health and Family Welfare, Government of India. Practical Handbook of Burns Management for National Programme for Prevention, Management and Rehabilitation of Burn Injuries (NPPMRBI) [Internet]. Available from: https://www.nhp.gov.in/ disease/skin/burns
2. Soares de Macedo JL, Santos JB. Nosocomial infections in a Brazilian Burn Unit. Burns. 2006; 32(4): 477-81.
3. Ahuja RB, Gupta A, Gur R. A prospective double blinded comparative analysis of Framycetin and Silver Sulphadiazine as topical agents for burn. A pilot study. Burns. 2009; 35(5): 672-6.
4. Vindenes HA, Ulvested E, Bjerknes R. Concentrations of cytokines in plasma of patients with large burns: their relation to time after injury, burn size, inflammatory variables, infection and outcome. Eur J Surg. 1998; 164(9): 647-56.
5. Alexander M, Chaudry IH, Schwacha MG. Relationships between burn size, immunosuppresion, and macrophage hyperactivity in a murine model of thermal injury. Cell Immunol. 2002; 220(1): 63-9.
6. Church D, Elsayed S, Reid O, Winston B, Lindsay R. Burn wound infec-tions. Clin Microbiol Rev. 2006; 19(2): 403-34.
7. Arturson M G. The pathophysiology of severe thermal injury. J Burn Care Rehabil.1985; 6:129-134.
8. krami A, Kalantar E. Bacterial infections in burn patients at a burn hospital in Iran. Indian J Med Res. 2007:126; 541-4.
9. Revathi G, Puria J, Jaid K. Bacteriology of burns. Burns 1998; 24 : 347-9.
10. Skoll PJ, Hudson DA, Simpson JA. Aeromonas hydrophila in burn patients. Burns 1998; 24 : 350-3.
11. Lawrence J. Burn bacteriology during the past 50 years. Burns 1994; 18 : 23-9.
12. Nudegusio L, Algimantas T, Rytis R, Minmdaugas K. Analysis of burn patients and the isolated pathogens. Lithuanian Surg 2004; 2 : 190-3.
13. Shahid M, Malik A. Resistance due to aminoglycoside modifying enzymes in Pseudomonas aeruginosa isolates from burns patients. Indian J Med Res 2005; 122; 324-9.
14. Karlowsky JA, Jones ME, Draghi DC, Thornsberry C, Sahm DF, Volturo GA. Prevalence and antimicrobial susceptibilities of bacteria isolated from blood cultures of hospitalized patients in the United States in 2002. Ann Clin Microbiol Antimicrob 2004; 3: 3-7.
15. Agnihotri N, Gupta V, Joshi RM. Aerobic bacterial isolates from burn wound infections and their antibiograms-a five- year study. Burns 2004; 30: 241-3.
16. Dasari H, Kumar A, Sharma BR. Burns septicemia The leading cause of burn mortality. J. Punjab Acad Forensic Med & Toxicol. 2008; 8(2):10-6.
17. Singh P, Harish D. Incidence of Post Burn Septicemia at a Tertiary Care Hospital. J Indian Acad Forensic Med. 2011;33(4):317–21.
18. Hosseini RS, Askarian M, Assadian O. Epidemiology of hospitalized female burns patients in a burn centre in Shiraz. East Mediterr Health J. 2007;13 (1):113-8.
19. David W, Albert T, Basil A. Infection of burn wounds. In: Bennett J, Brachman P, Hospital Infections, 4th ed. Philadelphia: Lippincott - Raven; 1998. p. 587-601.
20. Amin M, Kalantar E. Bacteriological monitoring of hospital borne septicemia in burn patients in Ahvaz, Iran. Burn Surgical Wound Care 2004; 3 : 4-8.
21. Kaur H, Bhat J, Anvikar AR, Rao S, Gadge V. Bacterial Profile of Blood and Burn Wound Infections in Burn Patients. Proceeding Natl Symp Tribal Heal. 1998;90-5.
22. Kandati J, Pathapati RM, Ponugoti M. Time related emergence of bacteria and their antibiogram of infected burns of patients during the hospital stay. Int.J.Curr.Microbiol.App.Sci. 2015; 4(1): 348-58.
23. Alghalibi, S. M. S.; Humaid, A.A.; Alshaibani, E. A. S. and Alhamzy, E. H. L. Microorganisms Associated With Burn Wound Infection in Sana’a, Yemen. Egypt. Acad. J. biolog. Sci. 2011;3(1): 19-25
24. Komolafe OO, James J, Kalongolera L, Makoka M. Bacteriology of burns at the Queen Elizabeth Central Hospital , Blantyre , Malawi.Burns. 2003; 29(3):235-8
25. Muhammad, N.S., Naheed, A., Iftikhar, H.K., Arif, B.M. and Faisal, W. 2012. Bacterial profile of burn
wound infections in burn patients. Ann. Pak. Inst. Med. Sci. 2012; 8(1): 54-57
26. Manjula, Dutta P, and Gupta V. “Bacterial isolates from burn wound infections and their antibiograms: A eight year study. Indian J of Plast Surg. 40.1 (2007): 25-28.
27. Song, Wonkeun, et al. “Microbiologic aspects of predominant bacteria isolated from the burn patients in Korea.” Burns 27.2 (2001): 136-139.
28. Nasser, Salah, Amr Mabrouk, and Ashraf Maher. “Colonization of burn wounds in Ain Shams University burn unit.” Burns 29.3 (2003): 229-233.