PATTERN OF RENAL PATHOLOGY IN FATAL VIPER BITE (DABOIA RUSSELLI): A MORTUARY BASED STUDY
Keywords:
viper bite, renal pathology, lesion types, cortical necrosis, glomerulopathy, autopsyAbstract
Envenomation due to poisonous snakebite is a significant cause of mortality in India as well as other agrarian South East Asian countries. Renal failure is consider the leading mechanism of death in poisonous snakebite. Studies from India have shown snakebite (especially viper bite) as an important cause of acute renal failure necessitating the use of dialysis as life saving measure The present study was designed to explore the pattern of renal involvement in fatal cases and its association with type of snake. Autopsy study was conducted on a series of 36 fatal cases of snakebite during a two-year period The study involved complete medico legal autopsy and postmortem histological examination on cases at the mortuary of a tertiary care medical college and hospital The investigation revealed renal involvement in 77.8 % of the cases of fatal viper (Daboia russelli) bites. Acute cortical necrosis was the major type of lesion (72.2 %) followed by tubular necrosis.
References
Dutta T.K., V. Mukta, Snake Bite. J Indian Med Assoc 2006; 104(5): 250–52.
Warrel D.A.,Snake bite. The Lancet 2010; 375(9708):77– 88.
Hati A.K., Mondal M., De M.K., Mukherjee M., Hati R.N., Epidemiology of snakebite in the district of Burdwan, West Bengal. J Indian Med Assoc1992; 90: 145–47.
Mittal B.V., Acute renal failure following poisonous snakebite. J Postgrad Med 1994; 40(3): 123–26. 5. Ali G., Kak M., Kumar M., Bali S.K., Tak S.I., Hassan G., et al. Acute renal failure following echis carinata (saw scaled viper) envenomation. Indian J Nephrol 2004; 14: 177–81.
Sakhuja V., Kohli H.S., Snake bite and acute renal failure. Saudi J Kidney Dis Transpl 2003; 14(2): 165-76. 7. Sitprija V., Snake bite nephropathy. Nephrology 2006; 11(5): 442–48.
Dutta T.K., Maruthi Ramana G. Snake Bite. In: Grover A, Aggarwal V, Gera P, Gupta R (editions). Mannual of Medical Emergencies. 2nd edition. Delhi: Pushpanjali Medical Publications. 2003: 107–14.
Bandyapadhyaay S.K., Ghosh S., Bandyapadhyaay R., Dutta A. Prognostic factors in haemotoxic viper bite; analysis of data from a referral hospital. J Indian Med Assoc 2009; 107(10): 12–13.
