STUDY OF SUDDEN DEATH DUE TO MALARIA IN MANGALORE – A MALARIA ENDEMIC ZONE IN SOUTH INDIA
Keywords:
Sudden death, Malaria, AutopsyAbstract
Malaria is one of the most common infectious diseases and an enormous public health problem. According to the World Malaria report 2008, about 247 million malaria cases were present worldwide among 3.3 billion people at risk in 2006, causing nearly a million deaths. This autopsy based retrospective study was carried out at Kasturba Medical College, Mangalore. Autopsy records of the cases autopsied during September 2004 to August 2008 were reviewed and cases confirmed of malaria after histopathological examination were included in the study. Out of 2515 cases autopsied during the study period, sudden death was reported in 274 cases, out of which five cases were confirmed as of sudden death due to malaria. The histopathology examination revealed infiltration of acute and chronic inflammatory cells with numerous parasitized RBCs containing malarial pigment in the visceral organs. Fatality due to malaria is seen even with good diagnostic facilities and treatment, especially in developing countries like India. Importance of complete autopsy and histopathological examination in identifying malaria related mortality is stressed.
References
World Malaria Report 2008.available online at www.who.int/malaria/wmr2008/malaria2008.pdf 2. Raghuram M. Malaria remains the scourge of people in Mangalore during Monsoon. The Hindu, 18th July 2007. Avialable online at http://www.thehindu.com/ 2007/07/18/stories/2007071860670300.htm 3. Rastogi P., Karki R.K., Disseminated malaria-Case Report. Indian Internet Journal of Forensic medicine & Toxicology 2009 (in press).
Menezes R.G., Kanchan T., Rai S., et al. An autopsy case of sudden unexplained death due to malaria. J Forensic Sci 2009 (in press).
Kasper D.L., Braunwald E., Fauci A.S., Hauser S.L., Longo D.L., Jameson J.L., Infectious diseases. Harrison’s Principles of Internal Medicine. 16th ed. Vol I. USA: Mc Graw Hill companies, 2005; pp 218–32.
Gilles H.M., Pathology of Malaria. Available online at www.aifo.it/english/.../malaria/6-Pathology% 20of%20malaria.pdf
Cotran R.S., Kumar V., Collins T., Infectious diseases. Robbins Pathologic basis of disease. 6th ed. Noida: Thomson Press Ltd, 2000 ; pp 389–391.
Malaria in Mangaluru. Avaiable online at http://www.malariasite.com/malaria/MalariaIn Mangalore.htm