MODERN TECHNIQUES FOR THE FORENSIC ANALYSIS OF DRUGS OF ABUSE

Authors

  • Payal Mutreja J1, First Floor, Amity Institute of Forensic Science, Amity University, Noida, Uttar Pradesh
  • Shruti Gupta J1, First Floor, Amity Institute of Forensic Science, Amity University, Noida, Uttar Pradesh
  • Kavita Goyal Assistant Director Chemistry Division, Forensic Science Laboratory, Rohini, Delhi
  • Sudhir Kumar Shukla Ex- Director Amity Institute of Forensic Science J1, First Floor, Amity Institute of Forensic Science, Amity University, Noida, Uttar Pradesh

Keywords:

sedatives, stimulants, hallucinogens, designing

Abstract

Globally drug abuse has become a serious issue in the recent past. The abuse of cocaine, amphetamines and methamphetamines has been observed the most. Over the years, Chromatography and Spectroscopy have been the commonly applicable analytical methods for analysing drugs of abuse. Nowadays, these methods are being Drugs of abuse, Chromatography, characterization and further application to matter whose lowest functional organization is at nanoscale levels (Palit and Datta, 2010). The particles having dimension of 1 to 100 nanometres are referred as nanoparticles (NPs). These NPs have beenof great scientific interest as they provide with a link between large-sized materials and their atomic  or molecular structures. Different nanodevices including sensors, tubes, chips, wires, etcare used in analysis purpose. 

References

Andreou C, Hoonejani MR, Barmi MR, Moskovits M, Meinhart CD. Rapid Detection of Drugs of Abuse in Saliva Using Surface Enhanced Raman Spectroscopy and Microfluidics. ACS Nano. 2013; 7 (8): 7157-7164.

Ansari N, Lodha A, Pandya A, Sutariya PG, Menon SK. Lab-on-phone citrate-capped silver nanosensor for lidocaine hydrochloride detection from a biological matrix. Anal Methods. 2015; 7 (21): 9084-9091.

Bell SEJ, Burns DT, Dennisa AC, Speers JS. Rapid analysis of ecstasy and related phenethylamines in seized tablets by Raman spectroscopy. Analyst. 2000; 125 (3): 541-544.

Bumbrah GS, Sharma RM. Raman spectroscopy – Basic principle, instrumentation and selected applications for the characterization of drugs of abuse. Egypt J Forensic Sci. 2016; 6 (3): 209-215.

Chen J, Jiang J, Gao X, Liu G, Shen G, Yu R. A New Aptameric Biosensor for Cocaine based on Surface Enhanced Raman Scattering Spectroscopy. Chem Eur J. 2008; 14 (27): 8374–8382.

Christodoulides N, Garza RDL, Simmons GW, McRae MP, Wong J, Newton TF, et al. Application of programmable bio-nano-chip system for the quantitative detection of drugs of abuse in oral fluids. Drug and Alcohol Depend. 2015; 153: 306-313.

Day JS, Edwards HGM, Dobrowski SA, Voice AM. The detection of drugs of abuse in fingerprints using Raman spectroscopy I: latent fingerprints. Spectrochim Acta A Mol BiomolSpectrosc. 2004; 60 (3): 563-568.

Dogaroiu C, Sugden R. Practical implications of GC and HPLC methods for the analysis of drugs of abuse in blood. Romanian J Leg Med. 2008; 16 (2): 95-102.

Filipponi L, Sutherland D. Introduction to Nanoscience and Nanotechnologies. Fundamental Concepts in Nanoscience and Nanotechnologies. Interdisciplinary Nanoscience Center (iNANO). Published 2010.

Hargreaves MD, Page K, Munshi T, Tomsett R, Lynch G, Edwards HGM. Analysis of seized drugs using portable Raman spectroscopy in an airport environment- A proof of principle study. J Raman Spectrosc. 2008; 39 (7): 873-880.

He M, Li Z, Ge Y, Liu Z. Portable Upconversion Nanoparticles-Based Paper Device for Field Testing of Drug Abuse.Anal Chem. 2016; 88 (3): 1530–1534.

Inscore F, Shende C, Sengupta A, Huang H, Farquharson S. Detection of Drugs of Abuse in Saliva by Surface-Enhanced Raman Spectroscopy (SERS).Appl Spectrosc. 2011; 65 (9): 1004-1008.

Karacic V, Skender L. Analysis of Drugs of Abuse in Urine by Gas Chromatography/ Mass Spectrometry: Experience and Application.ArhHig Rada Toksikol. 2000; 51: 389-400.

Klein DM, Pandey G, Blackwell B, Sperry K. Determination of Drugs and Metabolites in Raw Wastewater Using Liquid Chromatography-Mass Spectrometry. J Forensic Res. 2015; 6 (1): 1-5.

Kronstrand R, Nyström I, Strandberg J, Druid H. Screening for drugs of abuse in hair with ion spray LC–MS–MS. Forensic Sci Int. 2004; 145 (2–3): 183- 190.

Lad AN, Pandya A, Agrawal YK. Overview of Nano Enabled Screening of Drug-Facilitated Crime: A Promising Tool in Forensic Investigation. Trends Analyt Chem. 2016; 80: 458-470.

Maralikova B, Weinmann W. Confirmatory analysis for drugs of abuse in plasma and urine by high

performance liquid chromatography–tandem mass spectrometry with respect to criteria for compound identification. J Chromatogr B. 2004; 811 (1): 21-30.

Moeller MR, Steinmeyer S, Kraemer T. Determination of drugs of abuse in blood.J Chromatogr B. 1998; 713: 91-109.

Mueller CA, Weinmann W, Dresen S, Schreiber A, Gergov M. Development of a multi-target screening analysis for 301 drugs using a QTrap liquid chromatography/tandem mass spectrometry system and automated library searching. Rapid Commun Mass Spectrom. 2005; 19 (10): 1332-1338.

Murali Lab. Nanobiotech Research. Molecular Lego Nanosensors for targeted detection. School of Molecular Biosciences. Accessed August, 2017.

Nakashima K. Development and Application of highly sensitive High-Performance Liquid Chromatographic methods for analysis of Drugs of Abuse. Chromatography: The Society for Chromatographic Sciences. 2005; 26 (2): 1-11.

Nanoscience and Nanotechnologies: Opportunities and Uncertainties. The Royal Society and The Royal Academy of Engineering: page 6.Published July, 2004.

Palit S, Datta A. Future Healthcare: Bioinformatics, Nano-Sensors, and Emerging Innovations. Nanosensors: Theory and Applications. 2010: 247-312.

Parikh CK. In: Textbook of Medical Jurisprudence, Forensic Medicine and Toxicology, 6th edition, CBS Publishers and Distributors Pvt. Ltd: New Delhi,2012: 10.7.

Paterson S, Cordero R, McCulloch S, Houldsworth P. Analysis of urine for drugs of abuse using mixed mode solid-phase extraction and gas chromatography mass spectrometry. Ann Clin Biochem. 2000; 37: 690- 700.

Rouhania S, Haghgooc S. A novel fluorescence nanosensor based on 1,8-naphthalimide-thiophene doped silica nanoparticles, and its application to the determination of methamphetamine. Sens Actuators B Chem. 2015; 209: 957-965.

Ryder A, O’Connor G, Glynn T. Identifications and Quantitative Measurements of Narcotics in Solid Mixtures Using Near-IR Raman Spectroscopy and Multivariate Analysis.J Forensic Sci. 1999; 44 (5): 1013- 1019.

Samyn N, De Boeck G, Verstraete AG. The Use of Oral Fluid and Sweat Wipes for the Detection of Drugs of Abuse in Drivers. J Forensic Sci. 2002; 47 (6): 1380- 1387.

Sobrido MS, Lorenzo LR, Abalde SL, Fernández AG, Duarte MAC, Puebla RAA, Marzán, LML. Label-free SERS Detection of Relevant Bioanalytes on Silver-

coated Carbon Nanotubes: The case of cocaine. Nanoscale. 2009; 1 (1): 153-158.

Srividya B. Nanotechnology in Forensics and Its Application in Forensic Investigation. Res Rev J Pharm Nanotechnol. 2016; 4 (2): 1-7.

Vindenes V, Yttredal B, Øiestad EL, Waal H, Bernard JP, Mørland JG, Christophersen, AS. Oral Fluid is a Viable Alternative for Monitoring Drug Abuse: Detection of Drugs in Oral Fluid by Liquid Chromatography-Tandem Mass Spectrometry and

Comparison to the Results from Urine Samples from Patients Treated with Methadone or Buprenorphine. J Anal Toxicol. 2011; 35 (1): 32-39.

West MJ, Went MJ. Detection of Drugs of Abuse by Raman Spectroscopy.Drug Test Anal. 2010; 3 (9): 532- 538.

Zhang J, Wang L, Zhang H, Boey F, Song S, Fan C. Aptamer- Based Multicolour Fluorescent Gold Nanoprobes for Multiplex Detection in Homogeneous Solution. Small. 2010; 6 (2): 201-204.

Published

2022-01-30

How to Cite

MODERN TECHNIQUES FOR THE FORENSIC ANALYSIS OF DRUGS OF ABUSE . (2022). Journal of Forensic Medicine & Toxicology, 38(2), 118–125. Retrieved from https://acspublisher.com/journals/index.php/jfmt/article/view/17213