THE STUDY OF HEART DISEASES IN WESTERN MAHARASHTRA POPULATION
Keywords:
Sudden death, Autopsy, Forensic Pathology, Heart diseasesAbstract
Death is an inevitable part in life. Sudden or unexpected death is said to occur when a person not known to have been suffering from any dangerous disease, injury or poisoning is found dead or dies within 24 hours after the onset of terminal illness. In present study the postmortem examination were carried out and heart was dissected with inflow outflow methods of heart dissection and examined for gross changes in its structures, musculature, chambers, valves, coronary arteries. The heart was preserved in 10% formalin solution for histopathological examination. The histopathology reports received from pathology department was analyzed. Out of 182 cases of heart diseases studied 133 cases (73.08%) were male and 49 cases (26.92%) were female. Maximum 50 cases (27.45%) were observed in the age group 41-50 years. The atherosclerotic changes in coronary arteries were observed in 83 cases (45.59%). The signs of Ischemic heart disease were observed in 42 (23.08%) cases, The covering and layers of heart were affected in 19 cases (10.42%), the rarest condition pancarditis were observed in 1 case (0.55%). Left ventricular hypertrophy were seen in 16 cases (8.80%); replacement fibrosis in 10 cases (5.50%); hypertrophic obstructive cardiomyopathy (HOCM) were seen in 5 cases (2.74%) The involvement of valves of heart was observed in 3 cases (1.65%).
References
Hui D. Unexpected Death in Palliative Care: What to Expect When You are Not Expecting. Curr Opin Support Palliat Care. 2015; 9 (4): 369–374.
Reddy KSN. The essential of forensic medicine and toxicology, 33rd Edition, Jaypee brothers medical publishers (P) Ltd, 2014: 150-151.
Agrawal A. textbook of forensic medicine and toxicology, First Edition, Avichal publishing company, 2014; 170-171.
Sudden Cardiac Death (Sudden Cardiac Arrest) available from: https:my.clevelandclinic. Org /health / diseases/17522-sudden-cardiac-death-sudden cardiac-arrest. [Retrieved on 01 June 2022].
Roth A, Mensah G, Johnson C, addolorato G, Ammirati E, Baddour L. Global Burden of Cardiovascular Diseases and Risk Factors. Journal of American college of cardiology. 2020; 76(25).
Huffman M, Prabhakaran D, Fall C, Tondan N, Lakshmy R, Ramji S. Incidence of Cardiovascular Risk Factors in an Indian UrbanCohort: J Am Coll Cardiol. 2011; 57(17): 1765–1774.
Garg M, Aggarwal A, Kataria S. Coronary
Atherosclerosis and Myocardial Infarction An Autopsy Study, J Indian Acad Forensic Med. 2011; 33 (1): 39-42.
Kumar V, Abbas A. K, Aster JC, & Perkins JA. Robbins basic pathology Philadelphia, 8th Edition, Elsevier. 2010: 529-530.
Feld, K., Feld, D., Quandel, K. Banaschak S. Manner of death, causes of death and autopsies in infants, children and adolescents. Rechtsmedizin; 2022;1-8.
Byard RW. The Autopsy and Pathology of Sudden Infant Death Syndrome; SIDS Sudden Infant and Early Childhood Death: The Past, the Present and the Future. Adelaide (AU): University of Adelaide Press; 2018; 24.
Rafieian-Kopaei M, Setorki M, Doudi M, Baradaran A, Nasri H. Atherosclerosis: process, indicators, risk factors and new hopes. Int J Prev Med. 2014; 5(8): 927-946.
Coronary artery disease. https:// my.clevelandclinic.org/health/ diseases/ 16898- coronary- artery-disease. [Retrieved on 25 may 2022].
Gibbons RJ. Mycordial Ischemia in the Management of Chronic Coronary Artery Disease Circulation: Cardiovascular Imaging. 2021; 14(1): 82-91
Anderson JL, Morrow DA. Acute Myocardial Infarction N Engl J Med. 2017; 376: 21.
Xanthopoulos A, Starling R, C, Triposkiadis F. Mitral Valve Stenosis: Still a Clinical Challenge? Cardiology. 2018; 140: 45-46.
Otto CM, Prendergast B. Aortic-Valve Stenosis — From Patients at Risk to Severe Valve Obstruction N Engl J Med 2014; 371: 78.
Bornstein AB, Rao SS, Marwaha K. Left Ventricular Hypertrophy. [Updated 2021 Dec 19]. In: Stat Pearls [Internet]. Treasure Island (FL): Stat Pearls Publishing; 2022. Available from: https:// www.ncbi.nlm.nih.gov/books/NBK557534.
Hinderer S, Layland K. cardiac fibrosis – a short review of causes and therapeutic strategies; advanced drug delivery reviews. (2019); 146: 77–82.
ZasadaW,Bobrowska B, Plens K, Dziewierz A, Siudak Z, Surdacki A, Dudek D, Bartuœ S. Acute myocardial infarction in young patients Kardiol Pol. 2021; 79 (10):1093-1098.
Yang L., Wu H., Jin X. Study of cardiovascular disease prediction model based on random forest in eastern China. Sci Rep. 2020; 10; 5245.
Marwah N, Sethi B, Gupta S, Duhan A, Singh S, Sev R. Histomorphological Spectrum of Various Cardiac Changes in Sudden Death: An Autopsy Study, Iran J Pathol. 2011;v6(4): 179–86.
Siddiqui MI, Mahanta A, Umesh SR Neeha S, Sainath A. Morphological study of the spectrum of lesions encountered in the heart and coronaries on autopsy, Indian J Pathol Microbiol. 2022; 65: 18-22.
