Physiological Effects of Yoga and Pranayama on Serum Adipokines, Lipoprotein (a), Thyrotropin Levels, and Blood Pressure among Obese Hypothyroid Patients with Hypertension

Authors

  • Smitha R Varne Consultant Yoga, Naturopathy and Integrated Physician, Preksha Wellness and Yoga Centre, Rajiv Gandhi university of Health Sciences, Bangalore, India. Author
  • P A Balaji Consultant Physician and ESH Hypertension Specialist, Sakaria Hospital and Preksha Wellness and Yoga Centre, Rajiv Gandhi University of Health Sciences, Bangalore, India. Author

Keywords:

Adipokines, Hypertension, Hypothyroidism, Obesity, Pranayama, Yoga

Abstract

Background: The trio of obesity, hypothyroidism, and hypertension can act as a strong synergistic risk factor through  parameters, like elevated serum leptin and lipoprotein (a) and decreased adiponectin levels, for the development of  atherosclerotic diseases. Very few studies have focused on the effects of yoga/pranayama on these parameters among  obese hypothyroid patients with hypertension. Hence, the present research work was carried out to evaluate the  effects of 6 months of yoga and pranayama practices on these parameters.  Materials and Methods: The present interventional study was conducted involving 20 obese hypothyroid patients  with hypertension, their baseline values of serum adipokines, lipoprotein (a), thyrotropin-releasing hormone (TRH)  levels, blood pressure (BP), and body mass index (BMI) were recorded and they were subjected to 6 months of yoga/ pranayama and the same were recorded at the end of 6 months, and data were statistically analyzed.  Results: There was a statistically significant reduction (P < 0.01) between baseline versus after 6 months in  parameters such as serum leptin (23.94 ± 12.96 vs. 11.88 ± 10.32 ng/mL); serum lipoprotein (a) (28.45 ± 3.12 vs.  12.98 ± 3.56 mg/dL); BMI (29.42 ± 3.01vs. 25.36 ± 2.41 kg/m2); and significant improvement (P < 0.01) in serum  adiponectin (3.44 ± 2.32 vs. 8.86 ± 4.88 ug/mL); systolic BP (147.24 ± 7.39 vs. 126.88 ± 6.34 mmHg); diastolic BP  (95.76 ± 6.32 vs. 82.04 ± 4.56 mmHg); and TSH (13.41 ± 3.34 vs. 2.83± 2.62 mIU/L).  Conclusion: Yoga and pranayama practice for 6 months resulted in beneficial effects such as reduction of serum  leptin, lipoprotein (a) levels, BMI, BP, and improved adiponectin levels and thyroid functions among obese  hypothyroid patients with hypertension.

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Published

2023-08-31

How to Cite

Varne, S.R., & Balaji, P.A. (2023). Physiological Effects of Yoga and Pranayama on Serum Adipokines, Lipoprotein (a), Thyrotropin Levels, and Blood Pressure among Obese Hypothyroid Patients with Hypertension. International Research Journal of Ayurveda and Yoga, 6(8), 9–14. Retrieved from https://acspublisher.com/journals/index.php/irjay/article/view/12825