Efficacy and Safety of Tulsi Extract Mouthwash on Periodontal Health Status of Well-Controlled Type 2 Diabetes Mellitus Patients in India: A Concurrent Parallel Pilot Trial
Keywords:
Chlorhexidine, Dental Plaque, Diabetes Mellitus, Mouthwash, Periodontitis, TulsiAbstract
Background: One of the main risk factors for periodontitis is Diabetes Mellitus (DM). In patients with DM, maintaining optimal oral hygiene is crucial to managing the advancement of periodontitis. The adverse effects of chlorhexidine limit its long-term use. Tulsi is gaining more popularity due to its anti-inflammatory and antimicrobial properties. Studies related to Tulsi mouthwash in Type 2 DM patients are lacking. Objective: The aim of the study is to evaluate the efficacy of 6% Tulsi extract and 0.2% chlorhexidine mouthwashes on the periodontal health status of well-controlled type 2 DM patients. Materials and Methods: The present study is a concurrent, parallel, randomized controlled trial. A total of 38 participants aged 45–55 years were randomly allocated to two different groups. Group A and B participants were treated with 0.2% chlorhexidine and 6% Tulsi extract mouthwashes, respectively. The assessments of gingivitis (gingival Index), dental plaque (plaque Index), and periodontal pocket depth (Community Periodontal Index) were done at baseline and on the 15th day. An unpaired t-test was used to compare the clinical conditions of the two groups. Results: Both groups have individually shown a statistically significant reduction in gingivitis, dental plaque, and periodontal pocket depth. When both groups were compared on the 15th day, chlorhexidine mouthwash showed a statistically significant reduction in PI scores (Group A 0.79 vs. Group B 0.86). Conclusion: Tulsi mouthwash is as efficacious as chlorhexidine in reducing dental plaque, gingivitis, and pocket depth among well-controlled Type 2 DM patients.
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