Biochemical Studies On The Effect Of Aged Garlic Extract On Acetaminophen Induced Hepatotoxicity In Rats

Authors

  • M. Srikanth Department of Pathology, Veterinary College, Bangalore-24
  • M.L. Sathyanarayana Department of Pathology, Veterinary College, Bangalore-24
  • N. Chandrashekhara Department of Pathology, Veterinary College, Bangalore-24
  • K.P. Manjunath Department of Pathology, Veterinary College, Bangalore-24

Keywords:

Aged garlic extract, Acetaminophen, Amino transferases, Rats

Abstract

Aged garlic extract has been shown to protect rats against acetaminophen induced liver injury through its antioxidant property. Aged garlic extract was given orally to rats for a period of 28 days. Liver damage was induced by inoculating acetaminophen at 500 mg/kg on 12th day of the experimental study. In acetaminophen treated rats there was significant increase in serum amino transferases (ALT and AST), but these enzymes were in the normal range in aged garlic extract (AGE) treated group indicating the protective effect of aged garlic extract against acetaminophen induced injury. 

Downloads

Download data is not yet available.

Downloads

Published

2013-09-10

Issue

Vol. 9 No. 2 (2013): The Indian Journal of Veterinary Sciences and Biotechnology (IJVSBT) (Oct- Dec) 2013

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

Srikanth, M., Sathyanarayana, M., Chandrashekhara, .N., & Manjunath , K. (2013). Biochemical Studies On The Effect Of Aged Garlic Extract On Acetaminophen Induced Hepatotoxicity In Rats . Indian Journal of Veterinary Sciences and Biotechnology, 9(2), 9–11. Retrieved from https://acspublisher.com/journals/index.php/ijvsbt/article/view/3094