Induction of Parturition using Mifepristone and Misoprostol in Bitch with Single Pup Syndrome
DOI:
https://doi.org/10.48165/ijar.2023.44.01.14Keywords:
Mifepristone, misoprostol, radiograph, Single puppy syndromeAbstract
Single puppy syndrome is common in older bitch. It occurs mostly due to the death of embryos during early gestation and resorption before mineralization. A two-year-old Labrador bitch in her first parity was presented to the Veterinary Clinical Complex, Bihar Veterinary College, BASU, Patna with the history of breeding approximately 72 days ago. A lateral abdominal radiograph revealed single fully-grown fetus with anterior presentation in uterus. The bitch was treated with mifepristone and misoprostol for three days. After three days of treatment, bitch delivered a dead fetus and recovered uneventfully.
References
Borge, K.S., Tonnessen, R., Nodtvedt, A. and Indrebo, A. (2011). Litter size at birth in purebred dogs – A retrospective study of 224 dogs. Theriogenology,75: 911–919.
Cetin, Y., Macun, H.C., Beceriklisoy, H.B., Somi, S.S. and Aslan, S. (2010). Intravaginal application of misoprostol improves pregnancy termination with cabergoline and alfaprostol in dogs. Berl Munch Tierarztl Wochenschr. 123(5-6): 236-242.
Chaudhari, R.K., Sutaria, T.V., Chaudhari., C.F., Nakhashi, H.C. and Suthar, B.N. (2020). Effect of mifepristone and cabergoline in the termination of pregnancy in bitches. Ind. J. Anim Reprod., 41(1): 56-57
Jackson, P.G.G. (2004). Dystocia in the dog In: Hand book of Veterinary Obstetrics (ed), Saunders and Imprint of Elsevier Ltd. Edinbourgh, 2:141-166.
Jayakumar, C., Chinu, P.V. and Amritha, A. (2017). Challenges in management of canine high-risk pregnancies with single pup syndrome. Ind. J. Canine Pract., 9(1):22-26.
Johnston, S.D., Root Kustritz, M.V. and Olson, P.N.S. (2001). Canine parturition – Eutocia and dystocia. In: Canine and Feline Theriogenology (Johnston SD, Root Kustritz MV, Olson PNS, eds. Toronto) WB Saunders., pp 105 – 128.
Pitroda, M.H., Mali, A.B., Rangnekar, M.N., Amle, M.B. and Tumbare, P. J. (2019). Dystocia due to single pup syndrome in a Rottweiler she dog: a case report. Haryana Vet., 58 (Special Issue), 129-130.
Smith, F.O. (2007). Challenges in small animal parturition - Timing elective and emergency caesarian sections. Theriogenology, 68: 348 – 353.
Tang, O.S., Gemzell-Danielsson, K. and Ho, P.C. (2007). Misoprostol: Pharmacokinetic profiles, effects on the uterus and side-effects. Int. J. Gynaecol. Obst., 99: 160 – 167.