Corncob :A comfort to laboratory rodents  or A risk to research objectives ?

Bhavin R  Kansara; Jayant P Hole; Himanshu  Joshi; Pradeep B  Deshmukh

doi:10.48165/jlas.2020.3.1.7

Authors

Bhavin R Kansara Small Animal Facility for Experimentation (SAFE), Department of Biological Sciences, Indian Institute of Science Education & Research (IISER) Mohali, Sector 81, Mohali - 140306, Punjab Author
Jayant P Hole Experimental Animal Facility, Centre for DNA Fingerprinting and Diagnostics (CDFD), Opp. M.J. Market, Tuljaguda Complex, Nampally, Hyderabad - 500 001, Telangana Author
Himanshu Joshi NGSMIPS, Paneer Derlakhatte, Mangalore – 575018, Karnataka Author
Pradeep B Deshmukh Innova Consultancy Services,C-2/802, Kumar Shantiniketan, Sus-Pashan Road Walkeswar Chowk, Pashan, Pune – 411021, Maharastra Author

DOI:

https://doi.org/10.48165/jlas.2020.3.1.7

Keywords:

Corncob, estrogenic, endocrine disruption, mitogenic, hardwood chips

Abstract

Corncob has been the most common choice of bedding material for laboratory animals in many countries due to its ready availability, low cost and better absorbance properties. However, corncob has been reported to have estrogenic, endocrine disruption and mitogenic properties by few authors. Animal facilities need to make a wise decision while selecting a particular bedding type, such that the unwanted effects associated with bedding like corncob, may not interfere with the research objectives. Chip bedding made from hardwood is one of the most common choices of bedding by most international animal facilities for commercial breeders, academic research institutes, pharmaceutical industry and pre clinical contract research organisations.

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References

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