Foresight vision on exogenous applications of in vitro derived dsRNAs in Agriculture

Authors

  • Eltayb Abdellatef Commission for Biotechnology and Genetic Engineering, National Center for Research, Ministry of Higher Education and Scientific Research, P. O. Box 2404, Khartoum, Sudan

DOI:

https://doi.org/10.5958/2582-2683.2021.00009.5

Keywords:

RNAi, siRNA, dsRNA, gene silencing, environmental risks

Abstract

RNA interference (RNAi) is a gene regulatory mechanism that limits the transcript level by either suppressing transcription (transcriptional gene silencing [TGS]) or by activating a sequence-specific RNA degradation process (posttranscriptional gene silencing [PTGS]). The discovery of RNA silencing via RNAi has facilitated major recent breakthroughs in medicine, veterinary, agriculture, and environmental sciences. As such, the use of RNAi in agricultural fields presents an environmental friendly approach to generate pest- and pathogen-resistant crops. Spray-induced gene silencing (SIGS) provides an intelligent method of using double-stranded (ds)RNA as a trigger to silence target genes in pests and pathogens without side-effects like in the case of chemical pesticide use. This review examines the risks associated with accumulation of dsRNA and small interfering RNA (siRNA) in plants and invasive targeted organisms and environmental contamination, transgeneratioal gene silencing, dsRNA fate and future implementation of SIGS. 

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Published

2021-08-21

Issue

Vol. 16 No. 1 (2021): Journal of Eco-Friendly Agriculture (Jan-Jun) 2021

Section

Articles

How to Cite

Abdellatef, E. (2021). Foresight vision on exogenous applications of in vitro derived dsRNAs in Agriculture . Journal of Eco-Friendly Agriculture, 16(1), 52–57. https://doi.org/10.5958/2582-2683.2021.00009.5
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