SHRAMAHARA MAHAKASHAYA OF CHARAKA SAMHITA – A PROMISING  SUPPLEMENT FOR IMMUNOMODULATION – A SYSTEMATIC REVIEW

K N A Dharmasena; A Ramamurthy; Joshi  Krutika; Gaurav Sahrma

doi:10.48165/

Authors

K N A Dharmasena 1. MD scholar, Postgraduate department of DravyagunaVigyan,National Institute of Ayurveda, Jaipur Author
A Ramamurthy 2. Professor, Postgraduate department of DravyagunaVigyan,National Institute of Ayurveda, Jaipur Author
Joshi Krutika 3. Lecturer, Postgraduate department of DravyagunaVigyan, National Institute of Ayurveda, Jaipur Author
Gaurav Sahrma 4. Pharmacologist, Postgraduate department of DravyagunaVigyan, National Institute of Ayurveda, Jaipur Author

DOI:

https://doi.org/10.48165/

Keywords:

–Immuno-modulation, anti-fatigue formula, shramahara mahakashaya

Abstract

Immuno-modulation or modification of the immune responses towards wellbeing is incorporated as vyadhik shamatva, swasthya (wellbeing), bala(strength) and ojas in Ayurveda. Shrama (fatigue) is the main feature of balakshaya (Strength depletion), ojahkshaya (condition of depleting immunity) as well as rasa, asthi and shukradhatu kshaya (tissue depletions). Thereby, shrama and vyadhik shamatva

have a coexisting relation. Acharya Charaka has collectively mentioned 10 drugs as shramahara mahakashaya which works effectively in shrama. Ingredients of shramahara mahakashaya are rich in nutrients, antioxidants and also have proven effects on anxiety, and in immuno-modulation. Hence, this systematic review has been carried out to find the efficacy of shramahara mahakashaya in immuno-modulation. The study was carried out using thorough analysis of various Ayurveda classical texts as well as available modern literature and collected data & observations were presented in a scientific manner. The review will be beneficial to

understand and to modify the host immunity according to Ayurveda concepts.

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