Hypothyroidism And Stress- A Review Article

Sujata; Divya Gupta; Arun Gupta

doi:10.48165/

Authors

Sujata MD Scholar, PG dept. of Panchakrama, Ch. Brahm Prakash Charak Ayurveda Sansthan, Khera Dabar, New Delhi Author
Divya Gupta MD Scholar, PG dept. of Panchakrama, Ch. Brahm Prakash Charak Ayurveda Sansthan, Khera Dabar, New Delhi Author
Arun Gupta Head of the department, PG dept. of Panchakrama, Ch. Brahm Prakash Charak Ayurveda Sansthan, Khera Dabar, New Delhi Author

DOI:

https://doi.org/10.48165/

Keywords:

Hypothyroidism, Agni, Shodhan, Shaman, Stress

Abstract

Due to modernization and increased stress in daily life, life style have been changed which results into many endocrinal diseases, Hypothyroidism is one among them. Stress plays a major role in hypothyroidism pathogenesis. In Samhitas there is no direct reference of hypothyroidism but due to increased stress in our routine life it alters hypothalamus-pituitary-thyroid axis activity. In contemporary system of medicine, the drug of choice for Hypothyroidism is levothyroxine. Side effects of these drugs are increased hunger, muscle weakness, irregular periods, diarrhoea, excessive sweating, fever, hair loss, etc. In Ayurveda there is not any direct reference of chikitsa of hypothyroidism but it can be managed by using stress relieving and kapha vatahar chikitsa like shirodhara, abhyanga, various medhya rasyana. Laughter therapy and yoga also plays a major role in reducing stress. This study was carried out using through various ayurvedic classical text, pubmed, google scholar as well as available modern literature, collected data and observation were presented in a scientific manner. The review will be beneficial to understand the pathogenesis of hypothyroidism and modify the line of treatment of disease.

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References

. Mudur, G. (1999, January 23). Endocrine disorders remain undetected and untreated in India. Retrieved August 30, 2020, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1114720/

Cáp J. Hypothyroidism substitution and adrenal insufficiency in diabetic patients. Vnitrni lekarstvi. 2009 Apr;55(4):371.

.http://www.japi.org/thyroid_special_jan_issue_2011/article_01.html assess on 12-09- 15

Chrousos GP. Stressors, stress, and neuroendocrine integration of the adaptive response: The 1997 Hans Selye Memorial Lecture. Annals of the New York Academy of Sciences. 1998 Jun;851(1):311-35.

Weetman AP. Cellular immune responses in autoimmune thyroid disease. Clinical endocrinology. 2004 Oct;61(4):405-13.

. Chrousos GP, Elenkov IJ. Interactions of the endocrine and immune systems. Endocrinology. 4th ed. Philadelphia: Saunders. 2001:571-86.

Wilder, R.L., 1995. Neuroendocrine-immune system interactions and autoimmunity. Annu. Rev. Immunol. 13, 307—338

Kaviraja Ambikadutta Shastri,.Susrutasamhita of Maharshi Sushruta, Edited with Ayurveda-Tattva-Sandipika Published by Chaukhambha Sanskrit sansthan, Varanasi,edition reprint,2010,part-1,Sutra Sthana,Aturupakramaniya adhyaya 35/29,page no.172.

Dr.Brahmanada tripathi, Astangahrdyam of srimad vagbhata, edited with Nirmala hindi commentary by Chaukhamba Sanskrit pratisthan,Delhi,edition reprinted 2014, ShariraSthana, Angavibhagashariraadhyaya ,3/76,page no-380.

Commentry by Pt. Kashinath Shastri and Dr. Gorakhanath Chaturvedi;Agnivesha, Charak Samhita. Sutrasthana. Varanasi: Chaukhamba Bharti Academy; 1998. Vidyotini Hindi 16/13-16 page no 320-321

Cremaschi GA, Gorelik G, Klecha AJ, Lysionek AE, Genaro AM. Chronic stress influences the immune system through the thyroid axis. Life Sciences. 2000 Nov 17;67(26):3171-9.

. Silva JE 2000 Catecholamines and the sympathoadrenal system in thyrotoxicosis. In: Braverman LE, Utiger RD (eds),Werner and Ingbar’s The Thyroid: A Clinical and Funda-mental Text, 8thed. Lippincott Williams & Wilkins, Phila-delphia, pp. 642–651.

. Dluby RG 2000 The adrenal cortex in thyrotoxicosis. In:Braverman LE, Utiger RD (Eds), Werner and Ingbar’s TheThyroid: 8th ed. Lippincott Williams & Wilkins, Philadelphia, pp. 637–641

Kamilaris TC, DeBold CR, Johnson EO, Mamalaki E, List-wak SJ, Calogero AE, Kalogeras KT, Gold PW, Orth DN 1991Effects of short and long duration hypothyroidism and hy-perthyroidism on the plasma adreno corticotropin and corticosterone responses to ovine corticotropin-releasing hor-mone in rats. Endocrinology 128:2567–2576.

Silberman DM, Wald M, Genaro AM 2002 Effects of chronic mild stress on lymphocyte proliferative response. Participation of serum thyroid hormones and corticosterone. Int Immunopharmacol 2:487–497.

Dorshkind K, Horseman ND 2000 The roles of prolactin,growth hormone, insulin-like growth factor-I, and thyroid hormones in lymphocyte development and function: In sights from genetic models of hormone and hormone receptor deficiency. Endocr Rev 21:292–312

Bansode NM. “Hypothyroidism” In an Ayurvedic Perspective Review. 18. Ashtanga Hrudayam, Acharya Vagbhata, , Sarvangasundari, commentary, Chaukambha orientalia, reprint edition 2005, Sutrasthana - 11/2,Pg.182.

Ashtanga Hrudayam, Acharya Vagbhata, Sarvangasundari commentary, Chaukambha orientalia reprint edition 2005, Sutrasthana11/45,Pg 183.

. Ashtanga Hrudayam, Acharya Vagbhata, Sarvangasundari commentary, Chaukambha orientalia reprint edition 2005, Sutrasthana11/7,Pg 183

. WebMD Common and rare side effects for levothyroxine… (cited on 27/5/2016).

Rastogi S, Baiswar A, Nischal A, Srivastava PS, Nischal A. Effects of shirodhara in generalized anxiety disorder. TANG [HUMANITAS MEDICINE]. 2016 Nov 30;6(4):6-.

. Basler AJ. Pilot study investigating the effects of Ayurvedic Abhyanga massage on subjective stress experience. J Altern Complement Med. 2011;17(5):435-440. doi:10.1089/acm.2010.0281

Mukherjee A, Gombar V, Shamsi Y, Gupta M, Sinha S. Effectiveness of Brahmi in Various Illnesses: Review Paper. Herb Med. 2017;3(2):10.

Salve J, Pate S, Debnath K, Langade D. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo controlled Clinical Study. Cureus. 2019 Dec;11(12).

Vijaya Saraswathy T. Effectiveness of laughter therapy on stress among senior citizens in selected community setting at Kanchipuram district (Doctoral dissertation, Adhiparasakthi College of Nursing, Melmaruvathur).

Wadhwa R, Khandare M. Stress Management through Yoga. Global Journal of Human Social Science: A Arts & Humanities–Psychology. 2014;14(7).