Conceptual Study On Samprapti (Pathogenies) Of Śvitra w.s.r To Vitiligo

Shree Ram Saini; B K Sevatkar

doi:10.48165/

Authors

Shree Ram Saini Ph.D. Scholar , PG Department of Rog Nidan Evum Vikriti Vigyan National Institute Of Ayurveda Jaipur. Author
B K Sevatkar Associate Professor, PG Department of Rog Nidan Evum Vikriti Vigyan National Institute Of Ayurveda Jaipur Author

DOI:

https://doi.org/10.48165/

Keywords:

Svitra (Vitiligo), Vitiligo, Kustha

Abstract

Skin is the first organ of the body interacting with the environmental agents like physical, chemical & biological agents. Variations in the environmental stimuli & natural ability of body to deal with these factors result in spontaneous remissions & relapses. Interaction with these factors results in specific reaction pattern producing characteristic skin lesions in different parts of the body. Skin is a mirror that reflects internal & external pathology & thus helps in diagnosis of diseases. Skin ailments affects all ages from the neonates to the elderly & cause harm in a number of ways, such as discomfort, disfigurement, disability, etc. Svitra (Vitiligo) can be correlated with Vitiligo in contemporary medicine. Vitiligo is an autoimmune disease against melanocyte characterized by hypopigmented patches. In this review article describe the Ayurvedic Samprapti (Pathogenesis) in detail according to Ayurveda.

Downloads

Download data is not yet available.

References

https://www.nature.com/articles/nrdp20151 1

https://www.medicinenet.com/vitiligo/articl e.htm

https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC3215408/

http://www.iamj.in/posts/images/upload/25 17_2524.pdf

https://www.medicinenet.com/vitiligo/articl e.htm

Yadavji Trikamji Ācārya Charaksaṁhitā - Agnivesh. Elaborated by Charka & Dridhbala, With Āyurveda Dipika commentary of Cakrapāṇīdatta Nidan sthan 1/11 Caukhambā Krishnadas Academy ,Varansi print,2009.pp-897

Kaviraj Atridevgupta Vāgbhaṭṭa , Asthang Sangarha, Vol-1,Nidhan sthan14/2-3 printed - Caukhambā Krishnadas Academy ,Varansi 1993pp-908

Pandit Harihar Prasad Tripāṭhī Hārīta saṁhitā,‘ Haree Hindi Vyākhyā’ Tritiya Sthāna 39/50, 51 Caukhambā Krishnadas Academy ,Varansi print,2009. pp-678

Kent G, Al’Abadie M. Psychologic effects of vitiligo: a critical incident analysis. J Am Acad Dermatol 1996; 35:895–898.

Steel KP, Davidson DR, Jackson IJ. TRP 2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. Development 1992; 115:1111–1119

Kemp EH, Waterman EA, Weetman AP. Autoimmune aspects of vitiligo. Autoimmunity 2001; 34:65–77.

Pawelek J, Korner A, Bergstrom A, Bologna J. New regulators of melanin biosynthesis and the autodestruction of melanoma cells. Nature 1980; 286:617–619.

Spritz RA. The genetics of generalized vitiligo: Autoimmune pathways and an inverse relationship with malignant melanoma. Genome Med 2010;19;2:78

Morrone A, Picardo M, de Luca C, Terminali O, Passi S, Ippolito F. Catecholamines and vitiligo. Pigment Cell Res 1992;5:65-9.

Shaker OG, Eltahlawi SM, Tawfic SO, Eltawdy AM, Bedair NI. Corticotropin releasing hormone (CRH) and CRH receptor 1 gene expression in vitiligo. Clin Exp Dermatol 2016;41:734-40.

Vaccaro M, Cicero F, Mannucci C, Calapai G, Spatari G, Barbuzza O et al. L 33 circulating serum levels are increased in patients with non-segmental generalized vitiligo. Arch Dermatol Res 2016;308:527- 30.

Harris JE, Harris TH, Weninger W, Wherry EJ, Hunter CA, Turka LA et al. A mouse model of vitiligo with focused epidermal depigmentation requires IFN-g for autoreactive CD8+ T-cell accumulation in

the skin. J Invest Dermatol 2012;132:1869- 76.

Singh RK, Lee KM, Vujkovic-Cvijin I, Ucmak D, Farahnik B, Abrouk M et al. The role of IL-17 in vitiligo: A review. Autoimmun Rev 2016;15:397-404.

Laddha NC, Dwivedi M, Mansuri MS, Singh M, Gani AR, Yeola AP et al. Role of oxidative stress and autoimmunity in onset and progression of vitiligo. Exp Dermatol 2014;23:352-3.

Dr. Vikram Vir Bhushan, Dr. Varun Sharma, Dr Paramjeet Puri, Role of Panchakarma in public health scenario: A Review, IRJAY, October: 2020 Vol- 3, Issue-10; 304-312.

Hann SK, Chun W. Autocytotoxic hypothesis for the destruction of melanocytes as the cause of vitiligo. In: Hann SK, Nordlund J, editors. Vitiligo. Oxford: Blackwell Science Ltd.; 2000.

Gauthier Y, Cario Andre M, Taieb A. A critical appraisal of vitiligo etiologic theories. Is melanocyte loss a melanocytorrhagy? Pigment Cell Res 2003;16:322-32.

Adorini L, Penna G. Control of autoimmune diseases by the vitamin D endocrine system. Nat Clin Pract Rheumatol 2008;4:404-12.