Cervical Cancer and its Probable Ayurvedic Approach

Shalvi  Sharma; Bhagya Ranjan Dash; K Bharathi; Poonam Choudhary

doi:10.48165/

Authors

Shalvi Sharma P.G. Scholar, Dept. of Prasuti Tantra evam Stree Roga, National Institute of Ayurveda, deemed to be University (de novo), Jaipur, 302002 Author
Bhagya Ranjan Dash Ph.D. Scholar, Dept. of Roga Nidana evam Vikrikti Vigyana, National Institute of Ayurveda, deemed to be University (de novo), Jaipur, 302002 Author
K Bharathi Professor & HOD, Dept. of Prasuti Tantra evam Stree Roga, Dept. Prasuti Tantra evam Stree Roga, National Institute of Ayurveda, deemed to be University (de novo), Jaipur, 302002 Author
Poonam Choudhary Assistant Professor, Dept. of Prasuti Tantra evam Stree Roga, Dept. Prasuti Tantra evam Stree Roga, National Institute of Ayurveda, deemed to be University (de novo), Jaipur, 302002 Author

DOI:

https://doi.org/10.48165/

Keywords:

Ayurvedic measures, Cervical cancer, Human papilloma virus, Samprāpti.

Abstract

Cervical Cancer is the second most common cancer among women worldwide. Over 500,000 women worldwide die of cervical cancer annually. Human Papilloma Virus (HPV – mainly high risk type) is the main cause of cervical carcinogenesis. Worldwide, the prevalence of HPV in cervical tumors is 99.7%1. Approximately every 47 minutes a woman is diagnosed with cervical cancer. Among the 500,000 new cases each year, nearly 75% occur in developing countries1. Cervical cytological testing has reduced the incidence of cervical cancer by 70%1. As most of the cervical cancers are preventable so it become very important to diagnose them at an early treatable stage using appropriate diagnostic tools and finding new Ayurvedic measures to prevent and cure the disease so as to decrease the morbidity and mortality.

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References

Hull R, Mbele M, Makhafola T, Hicks C, Wang SM, Reis RM, Mehrotra R, Mkhize-Kwitshana Z, Kibiki G, Bates DO, Bates DO, et al: Cervical cancer in low and middle-income countries (Review). Oncol Lett 20: 2058- 2074, 2020

Chee Kai Chan, Gulzhanat Aimagambetova, Talshyn Ukybassova, Kuralay Kongrtay, Azliyati Azizan, "Human Papillomavirus Infection and Cervical Cancer: Epidemiology, Screening, and Vaccination—Review of Current Perspectives", Journal of Oncology, vol. 2019, Article ID 3257939, 11 pages, 2019. https://doi.org/10.1155/2019/3257939

Dutta DC, Text Book of Gynecology, Enlarged and Revised Reprint of 6th ed. Kolkata: New Central Book Agency (P) Ltd; 2013. Pg.323.

Nainakshi et al. “Risk Factors of Cervical Cancer: A Case Control Study.” Asia-Pacific journal of oncology nursing vol. 6,3 (2019): 308-314. doi:10.4103/apjon.apjon_73_18

Dutta DC, Text Book of Gynecology, Enlarged and Revised Reprint of 6th ed. Kolkata: New Central Book Agency (P) Ltd; 2013. Pg.326.

Dutta DC, Text Book of Gynecology, Enlarged and Revised Reprint of 6th ed. Kolkata: New Central Book Agency (P) Ltd; 2013. Pg.113.

Dutta DC, Text Book of Gynecology, Enlarged and Revised Reprint of 6th ed. Kolkata: New Central Book Agency (P) Ltd; 2013. Pg.324.

Dutta DC, Text Book of Gynecology, Enlarged and Revised Reprint of 6th ed. Kolkata: New Central Book Agency (P) Ltd; 2013. Pg.340.

Shastri AD, Acharya Sushruta, Sushruta Samhita (Nidana Sthana), Ayurveda Tatva Sandipika, Chaukhambha Sanskrit Series, 2014, p.354.

Shastri AD Acharya Sushruta, Sushruta Samhita (Shaareer Sthana), Ayurveda Tatva Sandipika, Chaukhambha Sanskrit Series, 2014, p.12.

Acharya YT, Shri Dalhana Acharya on Sushruta Samhita with Nibandha Samgraha commentary, Chaukhamba Surbharati Prakashan, Varanasi, 2008.

Shastri AD Acharya Sushruta, Sushruta Samhita (Shaareer Sthana), Ayurveda Tatva Sandipika, Chaukhambha Sanskrit Series, 2014, p.12.

Shastri K Acharya Charaka, Charaka Samhita (Chikitsa Sthana), Reprint, Varanasi, Chaukhambha Sanskrit Series, 2103, p. 870.

Shastri R Harita samhita, Prakashan, Varanasi Ed. 1985. 15. Shastri L, Yoga Ratnakar (Galaganda-granthi-arbudaadi Chikitsa), Hindi Commentary, Published by Chaukhambha Prakashan, Varanasi. reprint, 2013.

Reddy A.M, Myths And Facts About Consumption Of Ghee In Relation To Heart Problems - A Comparative

Research Study, International Journal of Pharmacy and Pharmaceutical Sciences, Vol 5, Suppl 2, 2013, ISSN 0975-1491

Charaka Samhita, Sutra Sthana, Annapanavidhi Adhyaya, 27/10, Available from:

https://niimh.nic.in/ebooks/ecaraka/?mod=read, Accessed on – 28-12-2021)

Mole S , A. Nalinakshan. Knowledge Attitude and Practice of Reproductive Health Care Between Generations and its Effect on Rajonivrithi. International Journal of Ayurveda and Pharma Research. 2017;5 (10):49-54.

David A. Elson, Rebeccah R. Riley, Ama Lacey, et al. Estrogen-induced Squamous Carcinogenesis Sensitivity of the Cervical Transformation Zone to Cancer Res 2000; 60:1267-1275.

Makwana D, IPGT & RA GAU Jamnagar, Gujarat, Management of Garbhashaya Mukhagata Vrana (cervical erosion) with Agnikarma by Swarna Shalaka, CTRI/2016/02/010661, 2019.

Shastri AD Acharya Sushruta, Sushruta Samhita (Sutra Sthana 14/40), Ayurveda Tatva Sandipika, Chaukhambha Sanskrit Series, 2014.

Jasmine. Management of Cervical Erosion by Agnikarma. AYURVEDAMRUTAM Newsletter. 1. 4.2012

Gupta P, Prathima, Role of Virechana Karma Inputraghni Yoni Vyapad W.S.R To Habitual Abortion - A Case Study, International Ayurvedic Medical Journal, (ISSN: 2320 5091) (April, 2017) 5 (4)

Divya CS, Pillai MR. Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis. Mol Carcinog. 2006;45(5):320-332. doi:10.1002/mc.20170

Buch ZM, Joshi J, Amonkar A, Vaidya AB. Interventional role of Haridra (Curcuma longa Linn) in cancer. Clin Cancer Investig J 2012; 1:45-50

Mahata S, Pandey A, Shukla S, et al. Anticancer activity of Phyllanthus emblica Linn. (Indian gooseberry): inhibition of transcription factor AP-1 and HPV gene expression in cervical cancer cells. Nutr Cancer. 2013;65 Suppl 1:88-97. doi:10.1080/01635581.2013.785008 [PubMed]

Habib. “Ginger extract (Zingiber officinale) has anti cancer and anti-inflammatory effects on ethionine-induced hepatoma rats.” Clinics (Sao Paulo, Brazil) vol. 63,6 (2008): 807-13. doi:10.1590/s1807-59322008000600017

Cohen, “Tulsi - Ocimum sanctum: A herb for all reasons.” Journal of Ayurveda and integrative medicine vol. 5,4 (2014): 251-9. doi:10.4103/0975-9476.146554

Munagala R, Kausar H, Munjal C, Gupta RC. Withaferin A induces p53-dependent apoptosis by repression of HPV

oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells. Carcinogenesis. 2011;32(11):1697-1705. doi:10.1093/carcin/bgr192 [PubMed]

F. Di Domenico, C. Foppoli, R. Coccia, M. Perluigi, Antioxidants in cervical cancer: Chemopreventive and chemotherapeutic effects of polyphenols, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1822, Issue 5, 2012, Pages 737-747, ISSN 0925- 4439

Akhtar A, Wang SX, Ghali L, Bell C, Wen X. Effective Delivery of Arsenic Trioxide to HPV-Positive Cervical Cancer Cells Using Optimised Liposomes: A Size and

Charge Study. Int J Mol Sci. 2018;19(4):1081. Published 2018 Apr 4. doi:10.3390/ijms19041081

Sun C, Nirmalananda S, Jenkins CE, et al. First ayurvedic approach towards green drugs: anti cervical cancer-cell properties of Clerodendrum viscosum root extract. Anticancer Agents Med Chem. 2013;13(10):1469- 1476. doi:10.2174/18715206113139990138 [PubMed]