A Critical Analysis on A Multipotent Drug Chandraprabha Vati -  Review Article

Preetimayee  Sahoo; Nihar Ranjan Mahanta

doi:10.48165/

Authors

Preetimayee Sahoo Assistant professor, Department of Kayachikitsa, Shri Babu Singh Jay Singh Ayurvedic Medical College and Hospital, Farrukhabad, UP. Author
Nihar Ranjan Mahanta Assistant professor, Department of Panchakarma, Shri Babu Singh Jay Singh Ayurvedic Medical College and Hospital, Farrukhabad, UP. Author

DOI:

https://doi.org/10.48165/

Keywords:

ChandraprabhaVati, rasapanchaka analysis, clinical

Abstract

ChandraprabhaVati is a very commonly used herbo-mineral preparation in day to-day practice being efficient in various disorders mostly genitor-urinary ones. Chandraprabha Vati is available in various ayurvedic texts with different preparations and different ingredients. The preparation, described by Sarangdhar Samhita and accepted by AFI, is being taken for a critical review of its properties, actions and its clinical efficacies in different diseases. It is made up of 37 ingredients with Shilajit and Guggulu present in maximum quantity 32 parts each. It is katu (73.38%) tikta (69.78%) in rasa, laghu (76.98%) ruksha (74.10%) in guna, ushna virya (70.50%), katu vipaka (69.06%) and tridosha shamak

predominantly Vatakapha shamak (91.37% and 84.89% respectively). This preparation is indicated in Prameha, Mutravahasrotaja vyadhi, Anaha, Shoola, Shwasa, Kasa, Shukradosha, Pandu, Kamala, GudagataVyadhi, Netraroga, Dantaroga, Kushtha and various other diseases as mentioned in different texts. Clinical studies have also proved its efficacy in various diseases. It is anti

diabetic, anti-inflammatory, anti-tumour, renal protective, hepato-protective, effective in jaundice and genitor-urinary diseases like UTI, dysmenorrhoea, PCOD, female infertility, etc. and many diseases are still left to be explored. Chandraprabha Vati is a multifaced drug and can be used in a variety of ailments successfully.

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References

. Tripathi B, Charaka Samhita, Commentary. Reprint ed. Varanasi: Chaukhamba Orientalia; 2006. pp. 755 2. The Ayurvedic Formulary of India, 2nd ed, Ministry of Health and Family Welfare, Govt. of India, Part I, Vati and Gutika: Chapter 12 (10). Delhi: Controller of Publications;2003. p.512-15.

Gupta G, Bharata Bhaishajya Ratnakara, Commentary. Reprint ed. New Delhi: B. Jain Publisher Pvt. Ltd; 2005. pp.152-155, 210-211

Kunte AM, editor, Astanga Hridaya, with Arunadatta. Sarvangasundara, Commentary. Reprint ed. Bombay: Nirnaya Sagar Press; 1939. pp. 236

Raju NK. Anti-inflammatory Prospective Study of Commiphora mukul (Guggulu) on Wistar Albino Rats [dissertation]. R.G.R. Sidhhanti College of Pharmacy: Jawaharlal Neheru Technological University; 2012.

Bhuvad, Sushama. (2012). Pharmaco-Therapeutic Profiles of Chandraprabhavati- An Ayurvedic Herbo-Mineral Formulation. International Journal of Pharmaceutical & Biological Archives, 2012; 3(6):1368-1375.

Singh R, Singh B, Kumarb N, Arora S. Antioxidant Activity of Triphala a Combination of Terminalia chebula, Terminalia bellerica And Emblica officinalis. Journal of Food Biochemistry,2010; 34: 222-232.

Desai VR, Kamat JP, Sainis KB. An immunomodulator from Tinospora cordifolia with antioxidant activity in cell free systems. J Chem Sci, 2002; 114: 713–719

Wanjari MM, Mishra S, Dey YN, Sharma D, Gaidhani SN, Jadhav AD. Antidiabetic activity of ChandraprabhaVati – A classical Ayurvedic formulation, Journal of Ayurveda and Integrative Medicine, 2016; 7(3): 144-150.

Bagul MS, Srinivasa H, Kanaki NS, Rajani M. Antiinflammatory activity of two Ayurvedic formulations containing guggul. Indian J Pharmacol, 2005; 37: 399-400.

Misar S, Management of Renal Parenchymal Disease in Ayurveda - A Case Study, International Journal of Science and Research, 2017; 6(2): 492-495

Dumbre RK, Kale AP, Kamble BM, Patil VR. Effect of Chandraprabha Vati in experimental prostatic hyperplasia and inflammation in rats. Journal of Pharmacy Research 2012; 5(12): 5302-04.

Winter CA, Risley EA, Nuss GW. Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs. Proceedings of the Society for Experimental Biology and Medicine. 1962;111(3):544-

Weerasekera KR, Dhammarathana I, Tissera AHM, Ratnasooriya WD. Anti- inflammatory activity of an ayurvedic herbo-mineral formulation: Chandraprabha Vati. International Journal of Recent Advances in Multidisciplinary Reasearch 2015; 2(6): 471-475

Bagul MS, Kanaki NS, Rajani M. Evaluation of free radical scavenging properties of two classical polyherbal formulations. Indian J Exp Biol, 2005; 43(8):732-6

Weerasekera KR, Ratnasooriya WD, Ranasingha P, Dhammarathana I, Tissera MHA, Ariyawansha HAS. Evaluation of Some Therapeutic Effects of Ayurvedic Hydromineral Formulation: ChandraprabhaVati. National Centre for Advanced Studies in Humanities and Social Sciences, Annual Research Symposium, 2014; 307-312

Saxena V, Srivastava N and Pandey N. Herbal drugs in benign prostrate hyperplasia (BPH). a current update. International Journal of Pharmaceutical Sciences & Research 2020;11(2): 580-586.

Gune PG, Ayurvediya Aushadhi Guna Dharma Shastra, Part 3, Delhi; Choukambha Sanskrit Sansthan: 2021, pp.13. 19. Namde MJ, Pathrikar AA, Kamat NM, Paradkar HS. Management of Pittaja Mutrakricchra by Ayurveda: A Case Study. International Journal of AYUSH Case Reports, 2021; 5(1): 7-12.

Kudari SV, Parvathy M. A comparative study of effect of Chandraprabha Vati & Gudamalaka Yoga in Pittaja Mutrakruchra w.s.r. to Lower UTI. Journal of Ayurveda and Integrated Medical Sciences, 2020; 5(3): 7-13.

Sahani S, Shekhar M, Bind S. Collision of ChandraprabhaVati in Mutrakrichha (Urinary tract infection) –a review. World Journal of Pharmaceutical research, 2020; 9(6): 319-327

Ratnasooriya WD, Weerasekera KR, Dhammarathana I, Tissera MHA, Ariyawansha HS. Diuretic Activity of Chandraprabha Vati (an Ayurvedic Herbo-mineral formulation) in Rats. World Journal of Pharmaceutical Sciences, 2014; 2(7):649-653

Yadav SR, Chavan D, Choudhari P. Role of Chandraprabha Vati in UTI. European Journal of Biomedical and Pharmaceutical Sciences, 2016; 3(7): 403- 405

Amle AJ, Havale AA. A clinical comparative study to evaluate the efficacy of rajah pravartaniVati in comparison with ChandraprabhaVati in udavarta yonivyapada w.s.r. spasmodic dysmenorrhoea. Ayurlog: National Journal of Research in Ayurved Science, 2014; 2(4): 1-9

Rodin AE, Crowson CN. Mercury nephrotoxicity in the rat. 2. Investigation of the intracellular site of mercury nephrotoxicity by correlated serial time histologic and histoenzymatic studies. American Journal of Pathology, 1962; 41(4): 485-99.

Agnihotri NS, Deshmukh JS. A Clinical Study on the Management of Fibroadenoma of Breast with Kanchanar Guggulu and Chandraprabha Vati. Aayushi International Interdisciplinary Research Journal, 2017; 4(8): 72-74

Palatty PL, Kamble PS, Shirke M, Kamble S, Revankar M, Revankar VM. A Clinical Round up of the Female

Infertility Therapy Amongst Indians. Journal of Clinical and Diagnostic Research, 2012 September (Suppl); 6(7): 1343-1349

Sowmyashree UP. Hypothyroidism - Ayurvedic interpretation and management - A Case Report. Journal of Ayurveda and Integrated Medical Sciences 2018; 3(3): 245-249.

Wanjari MM, Mishra S, Dey YN, Sharma D, Gaidhani SN, Jadhav AD. Antidiabetic activity of Chandraprabha vati - A classical Ayurvedic formulation. J Ayurveda Integr Med, 2016; 7(3): 144-150.

Weerasekera KR, Wijayasiriwardhena C, Dhammarathana I, Tissera MH, Ariyawansha HA. Establishment quality and purity of "ChandraprabhaVati" using sensory characteristics, physiochemical parameters, qualitative screening and TLC fingerprinting. International Journal of Herbal Medicine 2 (2014): 26-29.

Tripathi AK, Pandey SD, Sastry JLN, Vedula S. Observations on Clinical Safety of Chandraprabha Vati-An Ayurvedic Metallo-Herbo Mineral Formulation. Annals of Ayurvedic Medicine 2016; 5(1-2): 17-23

Palanivel V,Bindu BH, Fakruddin SB, Diwakar K, Ghouse SM, Salman BS, Kumar KC, Chaithanya B. Evaluation of Pharmacological Activity of ChadraprabhaVati on Serum of Albino Wistar Strain Rats. International Journal of Research In Phytochemical And Pharmacological Sciences 2019; 1(1): 28-38