Bheshajakaala and its Clinical Importance–A Review on the Physiological Basis
DOI:
https://doi.org/10.48165/Keywords:
Bheshajakaala, Vata, Bioavailability, Physiology, Ayurveda drug interactionsAbstract
The concept of time of administration of drugs (Bheshajakaala) is an important area in Ayurveda to be focused on. Even though the different types and indications of the different bheshajakaala are mentioned in classics how far they are executed in management of diseases by proper analysis is to be thought of. For the proper execution of these principles, there should be clarity and proper understanding of the concepts. The Ayurveda classics have given the details regarding drug administration viz. types, description of each type, conditions in which they are to be applied etc. but there is no direct reference regarding the exact reason for choosing these particular time period in particular condition. Here, an attempt is made to explain the logic of indicating each bheshajakaala in different conditions for the better understanding of the concept. The descriptions integrating modern physiological principles could prove pivotal in explaining the rationale for bheshajakaala and thereby facilitating their judicious use in clinical practice.
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References
Murthy RS, Vagbhata, Ashtanga Samgraha, Vol I Sutrasthana Ch.2 Ver.21, Varanasi: Chaukhambha Orientalia, 6th edition:2002.pp.27
Shastri AD, Susruta, Susruta Samhita, Sootrastana 34/23, Varanasi: Chaukhambha Sanskrit Sansthan, Reprint 2019.pp.167
Shastri P, Agnivesa, Charaka samhita of Acharya Charaka, Dridhabala krit, Chikitsasthana Ch.30 Ver.296; Varanasi: Chaukhambha Viswabharati, Reprint 2002.pp.880 4. Available
from:https://en.wikipedia.org/wiki/Bioavailability 5. Cadman B, Foods and meal plan for iron deficiency, Medical News Today, July 7 2021 available on https://www.medicalnewstoday.com/articles/322336 6. Melander A. Influence of Food on the Bioavailability of Drugs. Clin Pharmacokinet 3, 1978, 337–351. https://doi.org/10.2165/00003088-197803050-00001 7. K Sembulingam, Essentials of Medical Physiology, 8th edition, chapter 41,2009.pp. no.284
Acharya YT, Agnivesa, Charaka samhita of Acharya Charaka Dridhabala krit, edited, Chikitsasthana Ch.30 Ver.297; Varanasi: Chaukhambha Surbharatri prakashan, 2021.pp. 646
Acharya YT, Susruta, Sushruta Samhita, Uttartantra, Ch.64 Ver. 64, Varanasi: Chaukhambha Surbharatri prakashan; 2019.pp.813.
Tripathi B, Vagbhata, Ashtanga Hrudayam, Sootrasthana Ch.13 Ver.37-41, Varanasi: Chaukhambha Sanskrit Pratishthan, 2009.pp.190
Gupta A, Vagbhata, Ashtanga Samgraha, Vol.1 Sutrasthana Ch.23 Ver.12, publisher Krishna Das Academy, 2002.pp.181
Tripathi B, Sarngadharacharya, Sarngadhara Samhita, Poorvakhanda Chapter 2 verse 2, Varanasi: Chaukhambha Subhratri Prakashan, 2009.pp.18
Tripathi RD, Vriddha Vagbhata, Ashtang Sangraha, Sutrasthana Ch.23 Ver.12-22 Varanasi: Chaukhambha Sanskrit Pratishtan 2009.pp. 428-430
Tripathi B, Sarngadharacharya, Sarngadhara Samhita, Poorvakhanda Chapter 5 verse 2, Varanasi: Chaukhambha Subhratri Prakashan, 2009.pp.42
Murthy RS, Vagbhata, Ashtanga Samgraha, Vol I Sutrasthana Ch.19/ Ver.1, Varanasi: Chaukhambha Orientalia, 6th edition:2002.pp.349
Murthy RS, Vagbhata, Ashtanga Samgraha, Vol I Sutrasthana Ch.20 Ver.2, Varanasi: Chaukhambha Orientalia, 6th edition:2002.pp.368
Sastri VVS, Tridosha Theory, Published by Department of Publications, Arya Vaidya Sala, Kottakkal, 5th edition 2009.pp.89
Abhilash M, Lakshmi V, Aavaranam. 2nd ed. Kottakkal: Arya vaidya sala Publication Division; 2016. Pp.13- 22. 19. Shastri HS, Hemadri, Ayurveda Rasayana, Commentary on Ashtanga Hrudaya of Vagbhata,Paradakara Bhishagacharya, Sootrasthana Ch.13 Ver.37, Varanasi: Chaukhambha Subharatri Prakashan 2009.pp.218 20. Guyton and Hall, Textbook of Medical Physiology, 3rd South Asia edition, Section VI, Chapter 67.2009.pp.442 21. Shastri HS, Vagbhata, Ashtanga Hrudaya, Paradakara Bhishagacharya, Uttarasthana 2/38-40, Chaukhambha Subharatri Prakashan, 2009.pp.783