Clinico-Diagnostic Confirmatory and Therapeutic Investigation of Canine Pyometra

Authors

  • Krinal J Savaliya Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Junagadh-362001, Gujarat, India
  • Jignesh V Vadalia Assistant Professor & Head, Department of Veterinary Surgery and Radiology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, India.
  • Suresh V Mavadiya Department of Livestock Farm Complex, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Junagadh-362001, Gujarat, India
  • Raghuvir H Bhatt Veterinary Clinical Complex, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Junagadh-362001, Gujarat, India
  • Vinay A Kalariya Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Kamdhenu University, Junagadh-362001, Gujarat, India

DOI:

https://doi.org/10.48165/ijvsbt.22.3.25

Keywords:

Canine, Haematology, Ovariohysterectomy, Pyometra, USG, Vaginal discharge.

Abstract

A clinical study was conducted on 14 canine pyometra cases to evaluate clinico-physiological, haemato-biochemical, radiographic, and  ultrasonographic changes, bacteriological findings and treatment outcomes. Most cases occurred in dogs aged 6-10 years (64.28%),  with Spitz being the most commonly affected breed. Open-cervix pyometra (78.57%) was more prevalent than closed-cervix pyometra.  Common clinical signs included inappetence (92.85%), vaginal discharge (78.57%), polydipsia (78.57%), and polyuria (64.28%). The  elevated rectal temperature, total leukocyte count, neutrophil percentage, serum creatinine, AST, and ALT levels were significantly  reduced after surgical treatment. Ultrasonography proved more reliable than radiography for diagnosis, successfully identifying all  cases. Bacterial culture revealed predominance of Gram-negative bacilli (64.28%), with the highest antibiotic sensitivity to levofloxacin  (57.14%) and chloramphenicol (50%). Ovariohysterectomy was the most effective treatment. Medical therapy alone was inadequate.  Post-operative complications included wound dehiscence, ecchymosis, and two fatalities due to systemic complications. 

Downloads

Download data is not yet available.

References

Ali, O. J., Hassan, A. H., Saeed, N. M., & Ali, T. G. (2023). Pyometra in dogs: Clinical, bacteriological and histopathological observations. Pakistan Veterinary Journal, 43(4), 643–650.

Anusha, K. (2021). Clinico-diagnostic studies and evaluation of certain biomarkers in canine pyometra (Ph.D. Thesis). Sri Venkateswara Veterinary University, Tirupati, Andhra Pradesh, India.

Bigliardi, E., Parmigiani, E., Cavirani, S., Luppi, A., Bonati, L., & Corradi, A. (2004). Ultrasonography and cystic hyperplasia–pyometra complex in the bitch. Reproduction in Domestic Animals, 39(3), 136–140.

Fieni, F., Topie, E., & Gogny, A. (2014). Medical treatment for pyometra in dogs. Reproduction in Domestic Animals, 49, 28–32.

Fransson, B. A. (2003). Systemic inflammatory response in canine pyometra (Doctoral dissertation). Washington State University, USA.

Gouru, R., Reddy, K. R., Reddy, K. C., & Raghavender, K. B. P. (2024). Physiological, haematological and biochemical parameters of bitches affected with closed and open cervix pyometra. International Journal of Veterinary Sciences and Animal Husbandry, 9(1), 783–786.

Goyal, A. (2022). Clinical appraisal of surgical affections of urogenital system in dogs (M.V.Sc. Thesis). Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya, Palampur, Himachal Pradesh, India.

Jitpean, S., Ambrosen, A., Emanuelson, U., & Hagman, R. (2016). Closed cervix is associated with more severe illness in dogs with pyometra. BMC Veterinary Research, 13(1), 11.

Karabolovski, N., Stojanovska, C., Dameski, P., Zdraveski, I., Pejcinovska, N., Ristevski, M., & Dodovski, P. (2023). Pyometra. Horizons – International Scientific Journal, 1(1), 91–96.

Kumar, R. S., Rasool, A., Umamageswari, J., Sarath, T., & Rangasamy, S. (2023). Ultrasonographic evaluation of canine pyometra. Journal of Dairy, Veterinary & Animal Research, 12(1), 5–6.

Lee, S. H., Cho, J. K., Shin, N. R., Kim, H. S., Yong, H. Y., Lee, K. N., & Hwang, W. S. (2000). Identification and antimicrobial susceptibility of bacteria from the uterus of bitches with pyometra. Korean Journal of Veterinary Research, 40(4), 763–767.

Llazani, M., Qoku, A., & Dhaskali, L. (2021). Laboratory findings, vaginal cytology and histopathology in bitches with cystic endometrial hyperplasia–pyometra complex. European Journal of Biology and Biotechnology, 2(3), 61–63.

Manokaran, S., Napolean, R. E., Selvaraju, M., & Balasubramaniam, G. A. (2018). A comparative study on ultrasonographic and biochemical changes with histopathological changes of uterus in pyometra affected bitches. International Journal of Livestock Research, 8(12), 188–193.

Martins, D. G., Apparicio, M., & Vicente, W. R. R. (2015). A survey of three years consultation: 119 cases of pyometra, prognosis and outcome. Journal of Animal Science Advances, 5(2), 1202–1207.

Paudel, M., Kafle, S., Gompo, T. R., Khatri, K. B., & Aryal, A. (2023). Microbiological and hematological aspects of canine pyometra and associated risk factors. Heliyon, 9(12), 1–12.

Pitroda, M., Singh, A. K., Singh, R., Kumar, A., Honparkhe, M., & Singh, S. (2025). A retrospective study of pyometra in canines. The Indian Journal of Animal Reproduction, 46(2), 84–91.

Talukdar, D., Sarma, K., Konwar, B., Tolenkhomba, T. C., Talukdar, P., Islam, S. J., & Garg, A. (2022). Clinico-haemato-biochemical and pathological alteration of pyometra in canines. Indian Journal of Animal Research, 44, 1–7.

Verstegen, J., Dhaliwal, G., & Verstegen-Onclin, K. (2008). Mucometra, cystic endometrial hyperplasia, and pyometra in the bitch: Advances in treatment and assessment of future reproductive success. Theriogenology, 70(3), 364–374.

Published

2026-04-21

How to Cite

Savaliya, K. J., Vadalia, J. V., Mavadiya, S. V., Bhatt, R. H., & Kalariya, V. A. (2026). Clinico-Diagnostic Confirmatory and Therapeutic Investigation of Canine Pyometra . Indian Journal of Veterinary Sciences and Biotechnology, 22(3), 130-136. https://doi.org/10.48165/ijvsbt.22.3.25