In Vivo Evaluation of Saccharomyces cerevisiae for Reducing Milk Aflatoxin M1 in Dairy Cattle

Authors

  • Shweta MVSc Scholar, Animal Nutrition Division, ICAR-National Dairy Research Institute, Karnal-132001, Haryana, India.
  • Ram Singh Animal Nutrition Division, ICAR-National Dairy Research Institute, Karnal-132001, Haryana, India
  • Raman Malik Animal Nutrition Division, ICAR-National Dairy Research Institute, Karnal-132001, Haryana, India
  • Sonu Choudhary Animal Genetics and Breeding Division, ICAR-National Dairy Research Institute, Karnal-132001, Haryana
  • Dhruba Malakar Animal Biotechnology Division, ICAR-National Dairy Research Institute, Karnal-132001, Haryana
  • Hirikyathanahalli Vishweswaraiah Raghu Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal-132001, Haryana

DOI:

https://doi.org/10.48165/ijvsbt.22.2.08

Keywords:

Aflatoxin B1, Aflatoxin M1, Dairy cattle, Milk safety, Mycotoxin detoxification Saccharomyces cerevisiae

Abstract

Aflatoxin B1 (AFB1) contamination in livestock feed poses a significant risk to animal health and dairy product safety due to its conversion to aflatoxin M1 (AFM1) in milk. This study evaluated the efficacy of Saccharomyces cerevisiae in mitigating aflatoxin toxicity and reducing AFM1 carry-over in milk of lactating Sahiwal cows. Twenty cows, uniform in body weight (400-500 kg), lactation number (3-6), and early lactation stage (1-4 months), were randomly assigned to four treatment groups. Animals in T1 group received basal feed (TMR), while T2-T4 groups received Saccharomyces cerevisiae in feed @ 0.05, 0.10 and 0.20%, respectively. Milk yield, AFM1 excretion, carry over rate, somatic cell count (SCC), biochemical, and haematological parameters were measured. Yeast supplementation significantly improved dry matter intake and milk yield, reduced AFM1 excretion and carry-over rate, and decreased SCC (p<0.05). Biochemical and haematological parameters indicated alleviation of aflatoxin-induced hepatic damage and suppression of red and white blood cells. The highest efficacy was observed at 0.1-0.2% yeast inclusion. These findings demonstrate that Saccharomyces cerevisiae effectively reduces AFM1 contamination in milk while improving animal performance and health, offering a practical strategy for enhancing milk safety in aflatoxin-exposed dairy systems.

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Published

2026-03-10

Issue

Vol. 22 No. 2 (2026): The Indian Journal of Veterinary Sciences and Biotechnology (IJVSBT) (Mar-Apr) 2026

Section

Research Article

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Copyright (c) 2026 Indian Journal of Veterinary Sciences and Biotechnology

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How to Cite

Shweta, Singh, R., Malik, R., Choudhary, S., Malakar, D., & Raghu, H. V. (2026). In Vivo Evaluation of Saccharomyces cerevisiae for Reducing Milk Aflatoxin M1 in Dairy Cattle . Indian Journal of Veterinary Sciences and Biotechnology, 22(2), 41-45. https://doi.org/10.48165/ijvsbt.22.2.08