Clinical, Haemato-Biochemical and Ultrasonographic Evaluation of Ascites of Hepatic Origin in Dogs
DOI:
https://doi.org/10.48165/ijvsbt.22.3.23Keywords:
Ascites in dogs, Hepatic disease, Serum Ascites Albumin Gradient (SAAG), UltrasonographyAbstract
This study evaluated ascites of hepatic origin in dogs through haemato-biochemical profiling, ultrasonography and peritoneal fluid analysis to establish reliable diagnostic indicators. Twenty-four dogs with confirmed hepatic ascites presented to the Veterinary Clinical Complex, Veterinary College, Shivamogga (January-June 2025) were included in the study. Clinical signs included abdominal distension (100%), anorexia (83.3%), epigastric pain (50%) and diarrhoea (45.8%). Haematology revealed significant reductions in haemoglobin, packed cell volume and erythrocyte count, with leukocytosis, while platelet counts remained unchanged. Biochemical analysis showed marked elevations in ALT, ALP, GGT, LDH and C-reactive protein, with non-significant decrease in total protein, albumin and globulin. Ascitic fluid was typically clear, low-protein transudate with serum-ascites albumin gradient (SAAG) >1.1 g/dL, confirming hepatic involvement. Cytology revealed mesothelial cells and leukocytes. Ultrasonography consistently demonstrated peritoneal effusion, hepatomegaly, altered echogenicity and gallbladder wall changes. The integration of clinical, laboratory and imaging findings provides a comprehensive diagnostic framework for characterizing hepatic ascites in dogs, enhancing accuracy in differentiating it from other etiologies.
Downloads
References
Alleman, A. R. (2003). Abdominal, thoracic and peritoneal effusion. Veterinary Clinics of North America: Small Animal Practice, 33, 89–118.
Bhatti, A. K. (2020). Investigations on ascites in dogs (Ph.D. Thesis). Himachal Pradesh Krishi Vishva Vidyalaya, Palampur, India.
Burk, R. L., & Feeney, D. A. (2003). Small animal radiology and ultrasonography (Chapter 3, pp. 249–476). WB Saunders.
Bush, B. M. (2002). Interpretation of laboratory results for small animal clinicians. Blackwell Science Ltd., Oxford, UK.
Cocker, S., Richter, K., Ettinger, S. J., Feldman, E. C., & Cote, E. (2017). Diagnostic evaluation of the liver. In Textbook of veterinary internal medicine: Diseases of the dog and cat (8th ed., pp. 1611–1621). Elsevier.
Craig, S. M., Fry, J. K., Rodrigues Hoffmann, A., Manino, P., Heilmann, R. M., Suchodolski, J. S., Steiner, J. M., Hottinger, H. A., Hunter, S. L., & Lidbury, J. A. (2016). Serum C-reactive protein and S100A12 concentrations in dogs with hepatic disease. Journal of Small Animal Practice, 57(9), 459–464.
Hassan, M. S. M., Abdel-Saeed, H., Abd El Aziz Ahmed, K., & Abdou, O. M. (2022). Clinical and hemato-biochemical studies on canine anaemia. Advances in Animal & Veterinary Sciences, 10(4), 838–844.
Jain, S., Jyotsana, S., Naresh, C., & Ashish, S. (2013). Haemato-biochemical changes and therapeutic aspects of ascites with hepatic involvement in dogs. Environment and Ecology, 31(2C), 1205–1206.
Kumar, S. K., Ahuja, A. A., Bihani, D. K., & Gahlot, A. K. (2003). Studies on canine ascites. Journal of Canine Disease Research, 3(2), 9–17.
Mannion, P. (2006). Diagnostic ultrasound in small animal practice (1st ed., pp. 51–80). Blackwell Publishing Company, UK.
Patel, M. D., Parikh, P. V., & Barot, H. M. (2022). Clinical, ultrasonographic and haemato-biochemical assessment of liver and gall bladder affections in dogs. Indian Journal of Veterinary Surgery, 18(1), 65–71.
Phom, O. K., Sarma, K., Arya, R. S., Behera, S. K., Konwar, B., Saikia, B., Chaudhary, J. K., Rajesh, J. B., Prasad, H., & Das, H. (2019). Ascites and hepato-renal syndrome in cirrhosis in dogs. Journal of Entomology & Zoological Studies, 7(5), 313–321.
Rothuizen, J. (2009). Important clinical syndromes associated with liver disease. Veterinary Clinics of North America: Small Animal Practice, 39(3), 419–437.
Runyon, B. A., Montano, A. A., & Akriviadis, E. A. (1992). The serum ascites albumin gradient is superior to the exudates-transudate concept in the differential diagnosis of ascites. Annals of Internal Medicine, 117(3), 215–220.
Saravanan, M., Mondal, D. B., Sarma, K., Mahendran, K., Vijayakumar, H., & Sasikala, V. (2014a). Comprehensive study of haemato-biochemical, ascitic fluid analysis and ultrasonography in the diagnosis of ascites due to hepatobiliary disorders in dogs. Indian Journal of Animal Sciences, 84(5), 503–506.
Saravanan, M., Mondal, D. B., Sharma, K., Mahendran, K., & Sasikala, V. (2014b). Utility of serum ascites albumin gradient in dogs as an indicator of hepatobiliary disorders-induced ascites. Indian Veterinary Journal, 91(4), 33–35.
Singh, S. K., Shukla, S. K., Bhatt, P., & Singh, A. K. (2019). Clinico-therapeutic studies on ascites in canines. International Journal of Current Microbiology & Applied Sciences, 8(9), 1120–1137.
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Indian Journal of Veterinary Sciences and Biotechnology

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

