Osteosarcoma with Pulmonary Metastasis in a German Shepherd Dog
DOI:
https://doi.org/10.48165/ijvsbt.21.1.28Keywords:
invasiveness , Osteosarcoma , metastasesAbstract
Osteosarcoma is the most common bone tumor in the dogs with highest incidence among bone neoplasms and exhibits aggressive behaviour characterized by both local invasiveness and distant metastases (Cavalcanti et al., 2004; Withrow and Vail, 2007). Osteosarcoma can arise in any bone of appendicular skeleton, in the following order of frequency: humerus, radius, ulna, femur, and tibia (Liu et al., 1977). Osteosarcoma is a highly metastatic neoplasia, mainly towards the lungs, with 90% of the animals developing metastases within one year after limb amputation (Brodey and Riser, 1969). Some breeds like Doberman Pinscher, Saint Bernard, German Shepherd, Golden Retriever, Great Dane and Irish Setter are described as having an increased risk of developing osteosarcoma (McNeill et al., 2007; Morello et al., 2010). The present paper describes appendicular osteosarcoma with metastasis of lungs in 12 year old German shepherd dog.
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Brodey, R.S., & Riser, W.H. (1969). Canine osteosarcoma: A clinicopathologic study of 194 cases. Clinical Orthopaedics, 62(4), 26-32.
Cavalcanti, J.M., Amstalden, E.M.I., Guerra, J.L., & Magna, L.C. (2004). Osteosarcoma in dogs: Clinical-morphological study and prognostic correlation. Brazilian Journal of Veterinary Research & Animal Science, 41, 299-305.
Langenbach, A., Anderson, M.A., Dambach, D.M., Sorenmo, K.U., & Shofer, F.D. (1998). Extra-skeletal osteosarcomas in dogs: A retrospective study of 169 cases (1986-1996). Journal of American Animal Hospital Association, 34, 113-120.
Liu, S.K., Dorfman, H.D., Hurvitz, A.I., & Patnaik, A.K. (1977). Primary and secondary bone tumors in the dog. Journal of Small Animal Practice, 18(4), 313-326.
McNeill, C.J., Overley, B., Shofer, F.S., Kent, M.S., Clifford, C.A., Samluk, M., Haney, S., Van Winkle, T.J., & Sorenmo, K.U. (2007). Characterization of the biological behaviour of appendicular osteosarcoma in Rottweilers and a comparison with other breeds: A review of 258 dogs. Veterinary Comparative Oncology, 5, 90-98.
Morello, E., Martano, M., & Buracco, P. (2010). Biology, diagnosis and treatment of canine appendicular osteosarcoma: Similarities and differences with human osteosarcoma. The Veterinary Journal, 189, 268-277
Szewczyk, M., Lechowski, K., & Zabielska, K. (2014). What do we know about canine osteosarcoma treatment? A review. Veterinary Research Communication, 39, 61-67.
Thompson, K.G., & Pool, R.R. (2002). Tumors of bones. In: Tumors in Domestic Animals, 4th ed., Ed: Meuton D.J, Iowa State Press, Ames, IA, pp 245-317.
Withrow, S.J., & Vail, D.M. (2007). Withrow & MacEwen’s Small Animal Clinical Oncology. St Louis, MO: Saunders Elsevier.
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