Efficacy of Ivermectin and Combination of Eprinomectin with Fipronil against Demodicosis in Cats
DOI:
https://doi.org/10.48165/ijvsbt.20.4.36Keywords:
Cat, Demodicosis, Eprinomectin, Ivermectin.Abstract
Parasitic skin diseases are important part of feline dermatology in general. Feline demodicosis is caused by Demodex cati, Demodex gatoi and an unnamed species. The present investigation was conducted to diagnose and study the haemato-biochemical alterations and therapeutic efficacy of ivermectin and eprinomectin with Fipronil in feline demodicosis. Clinical examinations of gross lesions and microscopic examination of deep skin scrapings were used for diagnosis. Haematological study revealed microcytic hypochromic anaemia, leucocytosis with neutrophilia, lymphopenia and eosinophilia in most of cats with demodicosis which improved significantly following 28 days of treatment. No significant change in plasma AST-ALT activity was noted in cats affected with demodicosis. The efficacy of different therapeutic regimens was assessed based on disappearance of clinical symptoms and restoration of altered haemato biochemical parameters. It was found that both the regimen were effective for treatment of demodectic cats, however, the recovery rate was faster in group treated with spot on containing two acaricide drug eprinomectin and fipronil.
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