Anti-Bacterial Role of Asparagus Racemosus: A Review

Authors

  • Sanjeev Mittal RIMT University, Mandi Gobindgarh, Punjab, India Author

Keywords:

Antimicrobial peptides, Asparagus racemosus, Antimicrobial resistance, Cecropine A, extracts, paper disks, zone of inhibition

Abstract

The antimicrobial peptides (AMPs) are integral portion of the  human’s innate immune system showing broad-spectrum  antimicrobial roles. AMPs are used for antimicrobial therapy  due to the increase in the cases of resistance towards  conventional antibiotics. Unfortunately, resistance towards  AMPs and their derivatives are also showing an increase. In this  paper, the flowers of the vegetable Asparagus racemosus were  evaluated for its anti-microbial activity on two species of the  genus lactobacillus, Lactobacillus acetotolerans &  Lactobacillus acidifarinae. Firstly, various extracts of  Aqueous, methanol, ethanol, butanol were made. The AMP,  Cecropine A was chosen as positive control & the Dimethyl  sulfoxide (DMSO) was chosen as the negative control. Then  the paper discs were soaked in these extracts and were kept on  the lawn culture. After 24 hours, the ethanolic extract showed  the highest inhibition whereas DMSO showed the least activity.  These results open up possibility that this common vegetable  can be utilized for the commercial production of anti-microbial  agents.  

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References

. Stojkovikj S, Oklevski S, Jasuja OP, Najdoski M. Visualization of latent fingermarks on thermal paper: A new method based on nitrogen dioxide treatment. Forensic Chem. 2020;

. Bhatia R, Wadhawa D, Gurtu G, Gaur J, Gupta D. Methodologies for the synthesis of pentacene and its derivatives. Journal of Saudi Chemical Society. 2019.

. Lin YC, Lin CH, Chen CY, Sun SS, Pal B. Synthesis of electron deficient acene derivatives via a bidirectional iterative elongation reaction. Org Biomol Chem. 2011;

. Shabbir M. Textiles and clothing: Environmental concerns and solutions. Textiles and Clothing: Environmental Concerns and Solutions. 2019.

. Andersson DI, Hughes D, Kubicek-Sutherland JZ. Mechanisms and consequences of bacterial resistance to antimicrobial peptides. Drug Resistance Updates. 2016.

. Campos MA, Vargas MA, Regueiro V, Llompart CM, Albertí S, Bengoechea JA. Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides. Infect Immun. 2004;

. Spence JCH. Serial crystallography: Preface. Crystals. 2020.

. Chowdahry Z, Mehrotra S, Swarup N, Chowdhary F, Chowdhary A. Hemangioma-like telangiectatic granuloma: A diagnostic pitfall. J Exp Ther Oncol. 2018;

. Swarup N, Nayak MT, Chowdhary Z, Mehendiratta M, Khatana S, Choi SJ, et al. Evaluation and immunolocalization of BMP4 and FGF8 in odontogenic cyst and tumors. Anal Cell Pathol. 2018;

.Swarup N, Nayak MT, Arun N, Chandarani S, Chowdhary Z. Chronic non-healing ulcer of the oral cavity: tuberculosis or carcinoma? J Exp Ther Oncol. 2018;

.Swarup N, Nayak MT, Chowdhary Z, Chandarani S. Necrotising sialometaplasia: A diagnostic perplexity? An innocent entity to malignant masquerade. J Exp Ther Oncol. 2018;

.Trivedi N, Singh B, Jha KK. Ethanolic whole plant extract of farsetia jacquemontii showed antipyretic & analgesic potential in mice. Acta Pharm Sci. 2020;

.Chandak S, Agarwal A, Chaudhary M, Khan A, Saraswat S, Kumar A. Utility of sonographic parameters in prediction of obesity and their correlation with body mass index. J Clin Diagnostic Res. 2018;

.Agarwal A, Agarwal S, Verma A, Shukla RC. Total basal ovarian volume as a marker of ovarian reserve: Myth or reality. J Clin Diagnostic Res. 2018;

.Srivastava AK, Shukla S, Srivastava P, Dhole TN, Nayak MT, Nayak A, et al. Real time detection and quantification of Epstein Barr virus in different grades of oral gingivitis and periodontitis patients. J Exp Ther Oncol. 2018;

.Bechinger B, Gorr SU. Antimicrobial Peptides: Mechanisms of Action and Resistance. Journal of Dental Research. 2017.

.Bahar AA, Ren D. Antimicrobial peptides. Pharmaceuticals. 2013.

.Joo HS, Fu CI, Otto M. Bacterial strategies of resistance to antimicrobial peptides. Philos Trans R Soc B Biol Sci. 2016;

.Singh R, Geetanjali. Asparagus racemosus: a review on its phytochemical and therapeutic potential. Natural Product Research. 2016.

.Vasundra Devi PA, Divya Priya S. Antipyretic activity of ethanol and aqueous extract of root of Asparagus racemosus in yeast induced pyrexia. Asian J Pharm Clin Res. 2013;

.Onlom C, Khanthawong S, Waranuch N, Ingkaninan K. In vitro anti-Malassezia activity and potential use in anti dandruff formulation of Asparagus racemosus. Int J Cosmet Sci. 2014;

.Farjana A, Zerin N, Kabir MS. Antimicrobial activity of medicinal plant leaf extracts against pathogenic bacteria. Asian Pacific J Trop Dis. 2014;

.Batra P, Sharma AK. Anti-cancer potential of flavonoids: recent trends and future perspectives. 3 Biotech. 2013; [24].Bajpai S, Awasthi S, Dutta S, Mittal A, Kumar A, Ahmad F. Role of HER-2/neu in premalignant and malignant lesions of uterine cervix. J Clin Diagnostic Res. 2017;

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Published

2021-11-30

How to Cite

Anti-Bacterial Role of Asparagus Racemosus: A Review . (2021). International Journal of Innovative Research in Engineering & Management, 8(6), 314–318. Retrieved from https://acspublisher.com/journals/index.php/ijirem/article/view/11893