Vaccination in Chronic Kidney Disease: An Overview

Abstract

Infection are second leading reason of  mortality in individuals with end stages renal diseases,  behind cardiovascular disease, and they can cause  substantial morbidity in people with chronic kidney disease  at an earlier stage. Vaccines are a method of attempting to  decrease infection-related morbidity. Although individuals  with the CKD or ESRD might not react to immunization  and those without renal failures, sufficient seroresponse has  been reported with conventional or enhanced influenza,  pneumococcus, hepatitis B, or varicella vaccinations. With  normal dosage regimens, influenza seems to offer sufficient  protection. Despite the fact that some vaccinations are less  efficacious in individuals with CKD, there is growing  evidence that immunization is beneficial in these groups.  Vaccination rates, on the other hand, are low. Given the  growing body of data, quality improvement initiatives  aimed at improving immunization rate in the patient with  all stages of the CKD are required.