Rare Case Of Parathyroid Adenoma In 22 Years Old Female Patient

Authors

  • Charmi H. Savalia 2nd Year Resident Department of Pathology, Smt. N.H.L. Municipal Medical College, Ahmedabad.
  • Minesh B. Gandhi Associate Professor, Department of Pathology, Smt. N.H.L. Municipal Medical College, Ahmedabad.
  • Cherry K. Shah Professor and Head of Department of Pathology, Smt. N.H.L. Municipal Medical College, Ahmedabad.

DOI:

https://doi.org/10.48165/ijabms.2021.233720

Keywords:

Parathyroid adenoma, Primary hyperparathyroidism (PHPT), Parathormone (PTH)

Abstract

Background: Parathyroid adenoma is a benign tumour of parathyroid gland and most common cause of primary  hyperparathyroidism. Most common age group affected is 5-6th decade. Parathyroid adenoma  causes elevated level of parathormone hormone and serum calcium.  Method: A retrospective study was done in a case of 22 years old female having pathological fracture and  on examination found to have neck mass and was diagnosed as parathyroid adenoma of left inferior  gland with bone pathology. Patient undergone left inferior parathyroidectomy ,specimen was sent  to histopathology department and HPE confirmed the diagnosis of parathyroid adenoma. Patient  was followed up and did well after surgery. Observation: Parathyroid adenoma most commonly present as solitary gland enlargement and most common in  the inferior parathyroid glands (75%) followed by superior parathyroid glands (15%) and  anomalous position (10%). Of the latter 70% are in mediastinum and rest are in intra thyroid  location. It is mainly sporadic and more common in female with male to female ratio being 1:3.  Multi glandular adenomas are seen in familial syndromes and lithium induced PHPT.Conclusion:Parathyroid adenoma is a rare presentation in young adult. With correlation of clinical findings,  biochemical and radiological investigation and histopathological examination parathyroid  adenoma can be diagnosed easily.

References

Robbins And Cotran Pathologic Basis of Disease, South Asia Edition 9e volume II

Rosai & Ackerman’s Surgical Pathology First South Asia Edition volume 1

Christopher D.M. Fletcher Diagnostic Histopathology of Tumors fourth edition volume 1

Head and Neck Pathology 2008 Dec;2(4):305-308 published by Jacqueline A. Weineke and Alice Smith

Publication on Parathyroid adenoma by Samantha A Wolfe and Sandeep Sharma; Last update June 2020

Indian J Otolaryngol Head Neck Surg. 2014 Jan;66(1):114-117 published on 2012 Mar 4

Published

2021-08-25

How to Cite

Rare Case Of Parathyroid Adenoma In 22 Years Old Female Patient. (2021). Indian Journal of Applied-Basic Medical Sciences, 23(37), 227–231. https://doi.org/10.48165/ijabms.2021.233720