Drug Interactions Xenobiotic Metabolism: Edited by Alice Kunek

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ACS Books

Synopsis

Acute behavioural effects of co-administration of the illegal drug 3,4 methylenedioxymethamphetamine (MDMA, 7.5.mg/kg, s.c.) and the synthetic cannabinoid receptor agonist WIN55212-2 (WIN, 1.2mg/kg, i.p.) in rats were investigated. MDMA impaired performance on a T-maze effort-based decision making task. MDMA and MDMA+WIN treatment increased body temperature to a similar extent, whereas WIN increased temperature at an earlier time point. Locomotion, exploratory behaviour and food intake was comparable in MDMA and MDMA+WIN-treated animals. MDMA- the cannabinoid receptor agonist did not substantially modulate the MDMA-induced behavioural effects.

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Published

December 10, 2020

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Details about the available publication format: Paper Back

Paper Back

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How to Cite

Drug Interactions Xenobiotic Metabolism: Edited by Alice Kunek. (2020). ACS Publisher Books. https://acspublisher.com/books/index.php/acsbooks/catalog/book/4