Phytochemical screening and antibacterial activity of Acorus calamus Linn. rhizomes
Keywords:
Acorus calamus, Secondary metabolites, NMR, DPPH, α-AsaroneAbstract
Acorus calamus Linn., a member of the Acoraceae family, is often known as the Vacha (Sanskrit) and Sweet Flag (English). Acorus calamus rhizomes contain potential medicinal properties. The present study investigated the phytochemical screening and bioevaluation of crude extract as well as isolated and characterized molecules isolated from Acorus calamus rhizomes. Preliminary phytochemical study revealed that the extracts are rich in Alkaloids, Flavonoids, isoflavonoids, carbohydrates etc. The compound α asarone were isolated and characterized from the methanolic crude extract by using different physiochemical properties. The crude extracts as well as isolated and characterized molecule were evaluated at different concentrations against different bacteria (gam positive and gram negative)by using agar well diffusion method. Antioxidant potential of the crude extract and the pure molecule were evaluated by using standard tests. From this study, it was found that the extract as well as the pure molecule are potent in limiting the growth of different bacteria. The most potent were methanolic extract followed by ethyl acetate and ethanol. Thus, the anti-bacterial/ antioxidant properties of the crude extract and the pure compound(s) as reported in his work suggest a promising role of these compound(s), which needs to be precisely evaluated so as to increase their scope in drug discovery research.
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