Evaluation of Immunoglobulin Y (IgY) in Canine Parvoviral Enteritis Infected Dogs

Authors

  • Viswanathan Naveen kumar Veterinary Clinical Complex, Veterinary College and Research Institute, Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Theni 625534, Tamil Nadu, India
  • Porteen Kannan Veterinary Public Health and Epidemiology, Madras Veterinary College, TANUVAS, Chennai 600007, Tamil Nadu, India
  • Mangalanathan Vijaya Bharathi Veterinary Preventive Medicine, Madras Veterinary College, TANUVAS, Chennai 600007, Tamil Nadu, India
  • Pradeep Nag Southern Regional Station of National Diary Research Institute, Bengaluru 560030, Karnataka,
  • Veersami Maroudam Cisgen Biotech Discoveries Private Limited, IITM Research Park, Chennai, India
  • Balasubramanian Nagarajan Veterinary Preventive Medicine, Madras Veterinary College, TANUVAS, Chennai 600007, Tamil Nadu, India
  • Mohana Subramanian Bhaskaran Cisgen Biotech Discoveries Private Limited, IITM Research Park, Chennai, India

DOI:

https://doi.org/10.48165/ijvsbt.19.1.04

Keywords:

Canine Parvoviral Enteritis, Effective modality, Immunoglobulin Y, Supportive care, Therapy

Abstract

Canine Parvoviral Enteritis (CPE) is one of the enzootic canine viral diseases of dogs with huge morbidity and mortality even in vaccinated population. Low success rate and unpredictable prognosis of the existing symptomatic treatment regimen demands the need of new alternative regimen for the successful CPE therapy in dogs. In the present study, a total of 60 naturally infected canine parvoviral enteritis cases were divided into routine supportive care group (n=30) and Immunoglobulin Y (IgY) added supportive care group (n=30). In the IgY added group, enteric protected IgY tablets were used along with other usual symptomatic supportive treatment. Clinical parameters and survival rate was recorded until complete recovery from CPE. It was observed that IgY added supportive care group animals had significantly higher survival rate (83.33 %), lower mean clinical score and earlier recovery from the disease.

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References

Abbas, A. T., El-Kafrawy, S. A., Sohrab, S. S., & Azhar, E. I. (2019). IgY antibodies for the immunoprophylaxis and therapy of respiratory infections. Human Vaccines and Immunotherapeutics. 15(1), 264-275.

Bird, L., & Tappin, S. (2013). Canine parvovirus: where are we in the 21st Century?. Companion Animal, 18(4), 142-146.

Buonavoglia, C., Martella, V., Pratelli, A., Tempesta, M., Cavalli, A., Buonavoglia, D., Bozzo, G., Elia, G., Decaro, N., & Carmichael, L. (2001). Evidence for evolution of canine parvovirus type 2 in Italy. Journal of General Virology, 82(12), 3021-3025.

Castro, T. X., Miranda, S. C., Labarthe, N. V., Silva, L. E., & Cubel Garcia, R. C. (2007). Clinical and epidemiological aspects of canine parvovirus (CPV) enteritis in the State of Rio de Janeiro: 1995-2004. Arquivo Brasileiro de Medicina Veterinaria e Zootecnia, 59(2), 333-339.

Day, M. J., Horzinek, M. C., Schultz, R. D., & Squires, R. A. (2016). WSAVA Guidelines for the vaccination of dogs and cats. Journal of Small Animal Practice, 57(1), E1.

De Cramer, K. G. M., Stylianides, E., & Van Vuuren, M. (2011). Efficacy of vaccination at 4 and 6 weeks in the control of canine parvovirus. Veterinary Microbiology, 149(1-2), 126-132.

De Mari, K., Maynard, L., Eun, H. M., & Lebreux, B. (2003). Treatment of canine parvoviral enteritis with interferon-omega in a placebo-controlled field trial. Veterinary Record, 152(4), 105-108.

Decaro, N. (2020). Enteric Viruses of Dogs. Advances in Small Animal Care, 1, 143-160.

Decaro, N., & Buonavoglia, C. (2012). Canine parvovirus—a review of epidemiological and diagnostic aspects, with emphasis on type 2c. Veterinary Microbiology, 155(1), 1-12.

Decaro, N., Buonavoglia, C. B. V. R., & Barrs, V. R. (2020). Canine parvovirus vaccination and immunisation failures: Are we far from disease eradication. Veterinary Microbiology, 247, 108760.

Decaro, N., Desario, C., Campolo, M., Cavalli, A., Ricci, D., Martella, V., Tempesta, M., & Buonavoglia, C. (2004). Evaluation of lactogenic immunity to canine parvovirus in pups. The New Microbiologica. 27(4), 375.

Diraviyam, T., Zhao, B., Wang, Y., Schade, R., Michael, A., & Zhang, X. (2014). Effect of chicken egg yolk antibodies (IgY) against diarrhea in domesticated animals: a systematic review and meta-analysis. PLoS One, 9(5), e97716.

Kovacs-Nolan, J., & Mine, Y. (2012). Egg yolk antibodies for passive immunity. Annual Review of Food Science and Technology, 3, 163-182.

Liou, J., Shiau, J., Tai, C., & Chen, L. (2011). Production of egg yolk immunoglobulin against Escherichia coli from white leghorn and lohmann chickens. Journal of Animal Veterinary Advances, 10(18), 2349-56.

Martin, V., Najbar, W., Gueguen, S., Grousson, D., Eun, H. M., Lebreux, B., & Aubert, A. (2002). Treatment of canine parvoviral enteritis with interferon-omega in a placebo-controlled challenge trial. Veterinary Microbiology, 89(2-3), 115-27.

Mila, H., Grellet, A., Desario, C., Feugier, A., Decaro, N., Buonavoglia, C., & Chastant-Maillard, S. (2014). Protection against canine parvovirus type 2 infection in puppies by colostrum-derived antibodies. Journal of Nutritional Science, 3, e54.

Mine, Y., & Kovacs-Nolan, J. (2002). Chicken egg yolk antibodies as therapeutics in enteric infectious disease: a review. Journal of Medicinal Food, 5(3), 159-169.

Miranda, C., & Thompson, G. (2016). Canine parvovirus: the worldwide occurrence of antigenic variants. Journal of General Virology, 97(9), 2043-2057.

Mylonakis, M. E., Kalli, I., & Rallis, T. S. (2016). Canine parvoviral enteritis: an update on the clinical diagnosis, treatment, and prevention. Veterinary Medicine: Research and Reports, 7, 91.

Naveenkumar, V., Bharathi, M. V., Porteen, K., Selvaraju, G., & Vijayarani, K. (2019a). Factors Associated with the Occurrence of Canine Parvoviral Enteritis in Dogs. Journal of Animal Research, 9(6), 893-896.

Naveenkumar, V., Bharathi, M. V., & Nagarajan, B. (2019b). Heterogenous ImmunoglobulinY (IgY) Therapy: A New Modality in Canine Parvovirus Enteritis Treatment. Indian Veterinary Journal, 96(05), 76-77.

Naveenkumar, V., Nag, B. S. P., Porteen, K., Varun, A., Rani, R. U., Sasikumar, S., & Balasubramanyam, D. (2022). Utilization of Immunoglobulin Y (IgY) as Alternatives to Laboratory Animals in Human and Veterinary Medical Practice: A Review. Agricultural Review, DOI: 10.18805/ag.R-2479

Ogbu, K. I., Anene, B., Nweze, N. E., Okoro, J. I., Danladi, M., & Ochai, S. (2017). Canine Parvovirus: A Review. International Journal of Sciences and Applied Research, 2(2), 74-95.

Papaioannou, E., Soubasis, N., & Theodorou, K. (2013). The potential role of Oseltamivir in the management of canine parvoviral enteritis in 50 natural cases. Orally presented at: BSAVA Congress. pp. 4-7.

Pereira, M., Valério-Bolas, A., Saraiva-Marques, C., Alexandre-Pires, G., Pereira da Fonseca, I., & Santos-Gomes, G. (2019). Development of dog immune system: from in uterus to elderly. Veterinary Sciences, 6(4), 83.

Polanowski, A., Zabłocka, A., Sosnowska, A., Janusz, M., & Trziszka, T. (2012). Immunomodulatory activity accompanying chicken egg yolk immunoglobulin Y. Poultry Science, 91(12), 3091-3096.

Prittie, J. (2004). Canine parvoviral enteritis: a review of diagnosis, management, and prevention. Journal of Veterinary Emergency and Critical Care, 14(3), 167-176.

Savigny, M. R., & Macintire, D. K. (2010). Use of oseltamivir in the treatment of canine parvoviral enteritis. Journal of Veterinary Emergency and Critical Care, 20(1), 132-142.

Singh, D., Verma, A. K., Kumar, A., Srivastava, M., Singh, S. K., Tripathi, A. K., & Ahmed, I. (2013). Detection of canine parvovirus by polymerase chain reaction assay and its prevalence in dogs in and around Mathura, Uttar Pradesh, India. American Journal of Biochemistry and Molecular Biology, 3(2), 264-270.

Suartini, G. A., Suprayogi, A., Wibawan, W. T., Sendow, I., & Mahardika, G. N. (2014). Intravenous administration of chicken immunoglobulin has a curative effect in experimental infection of canine parvovirus. Global Veterinaria, 13, 801-808.

Sykes, J. E. (2014). Canine parvovirus infections and other viral enteritides. In: Canine and feline infectious diseases. pp. 141-151.

Van Nguyen, S., Umeda, K., Yokoyama, H., Tohya, Y., & Kodama, Y. (2006). Passive protection of dogs against clinical disease due to Canine parvovirus-2 by specific antibody from chicken egg yolk. Canadian Journal of Veterinary Research, 70(1), 62-64.

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Published

2023-01-10

Issue

Vol. 19 No. 1 (2023): The Indian Journal of Veterinary Sciences and Biotechnology (IJVSBT) (Jan- Feb) 2023

Section

Articles

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

kumar, V.N., Kannan, P., Bharathi, M.V., Nag, P., Maroudam, V., Nagarajan, B., & Bhaskaran, M.S. (2023). Evaluation of Immunoglobulin Y (IgY) in Canine Parvoviral Enteritis Infected Dogs. Indian Journal of Veterinary Sciences and Biotechnology, 19(1), 13–16. https://doi.org/10.48165/ijvsbt.19.1.04
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