Comparative Efficacy of Closantel and Azadirachta indica against Strongyle Infection in Goats
Keywords:
Anthelmintic efficacy, Goats, Neem seed, StrongyleAbstract
This study was carried out to evaluate the comparative efficacy of closantel and Azadirachta indica seed powder against strongyle infection in goats. Infected goats having >500 eggs per gram of faeces were included in the present study and divided into three groups (A, B, and C) of six goats each. Group A animals were treated with closantel @ 10 mg/kg b.wt., Group-B with neem seed powder @ 4 g/kg b.wt, Group C with neem seed powder @ 8 g/kg b.wt. Number of eggs per gram of faeces (EPG) were recorded on day 0 (before treatment), 7, 14, 21 and 28 day (post treatment). On the basis of EPG values, it was observed that closantel had more efficacy than neem seed powder as percent reduction in EPG was higher in closantel treated goats (91.12%) as compared to neem seed powder @ 8 g/kg body weight treated goats (62.49%). The efficacy of neem seed powder @ 4 g/kg b.wt was 38.09%. Thus, it was concluded that higher dose of neem seed powder has effective against strongyle infection in goats.
Downloads
References
Charles, T.P., Pompeu, J. and Miranda, D.B. (1989). Efficacy of three broad-spectrum anthelmintics against gastrointestinal nematode infections of goats. Veterinary Parasitology, 34(1- 2): 71-75.
Das, G., Dixit, A.K., Nath, S., Agrawal, V. and Dongre, S. (2015). Lev amisole and fenbendazole resistance among gastrointestinal nematodes in goats at Jabalpur, Madhya Pradesh. Journal of Veterinary Parasitology, 29(2): 98-102.
Dixit, A.K., Das, G., Dixit, P. and Sharma, R.L. (2019). Efficacy of herbal extracts and closantel against fenbendazole-resistant Haemonchuscontortus.Journal of helminthology, 93(5): 529-532.
Dongre, S., Das, G., Nath, S., Dixit, A.K. and Agrawal, V. (2015). Anthelmintic effeicacy of Azadirachta indica (neem) against strongyles in goats. The Indian Journal of Veterinary Sciences and Biotechnology, 10(3): 18-21.
Echevarria, F., Borba, M.F.S., Pinheiro, A.C., Waller, P.J. and Hansen, J. W. (1996). The prevalence of anthelmintic resistance in nematode parasites of sheep in Southern Latin America: Brazil. Veterinary Parasitology, 62(3-4): 199-206.
Gupta, M.K., Rao, M.L.V. Dixit, P., Shukla, P.C., Baghel, R.P.S. and Dixit, A.K. (2016b). Economic impact of anthelmintic therapy in goats naturally infected with gastrointestinal nematodes. Environment and Ecololgy, 34(4D): 2498-2500.
Gupta, M.K., Rao, M.L.V., Dixit, P., Shukla, P.C., and Dixit, A.K. (2016a). Prevalence of Gastrointestinal Nematodes in Goats in and around Jabalpur. Environment and Ecology, 34(4D): 2495- 2497.
Hoste, H., Chartier, C. and Le Frileux, Y. (2008). Control of gastrointestinal parasitism with nematodes in dairy goats by treating the host category at risk. Veterinary Research, 33: 531-545.
Iqbal, Z., Lateef, M., Jabbar, A. and Gilani, A.H. (2010). In vivo anthelmintic activity of Azadirachta indica A. Juss seeds against gastrointestinal nematodes of sheep. Veterinary parasitology, 168(3-4): 342-345.
Mahboob, K., Khan, J.A. and Khan, M.S. (2008). Prevalence, chemotherapy and haematology of strongylosis in horses of district layyah. J Anim Plant Sci, 18, 117-119.
Nwosu, C.O., Madu, PP and Richards, W.S. (2007). Prevalence and seasonal changes in the population of gastrointestinal nematodes of small ruminants in the semi-arid zone of north eastern Nigeria. Veterinary parasitology, 144(1-2): 118-124.
Radhakrishnan, L., Gomathinayagam, S. and Balakrishnan, W. (2007). Evaluation of Anthelmintic Effect of Neem (Azadirachta indica) Leaves on Haemonchuscontortus in Goats. Research Journal of parasitology, 2: 57-62.
Soulsby, E.J.L. (1982) Helminths, Arthropods and Protozoa of Domesticate Animals. 7th Edition, Balliere, Tindall and Cassel, London, 809 p.
Swarnkar, C.P., Singh, D., Khan, F.A. and Bhagwan, P.S.K. (2008a). Potential of alcoholic extract of Azadirachta indica bark as anthelmintic in sheep. Journal Veterinary Parasitology, 22(2): 13-16.
Tramboo, S.R., Shahardar, R.A., Allaie, I.M., Wani, Z.A. and Abbas, M. (2017). Efficacy of ivermectin, closantel and fenbendazole against gastrointestinal nematodes of sheep in Kashmir valley. Journal of Parasitic Diseases, 41(2): 380-382.
Westers, T., Bitton, A.J., Menzies, P., Leeuwen, J.V., Poljak, Z. and Peregrine, A.S. (2016). Efficacy of closantel against ivermectin and fenbendazole-resistant Haemonchus sp. in sheep in Ontario, Canada. Veterinary parasitology, 228: 30-41.
Yakubu, S., Saleh, U.A. and Abdullahi, G. (2006). In-vitro anthelmintic efficacy of crude aqueous extracts of neem (Azadirachta indica) leaf, stem and root on nematode. Animal Research International, 3(3): 549-552.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.