Diagnosis of Cardiovascular Renal Axis Disorder Subtype Hin Non-azotemic dogs

Authors

  • Rupalee S. Ghag Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala-680651, India
  • Madhavan Unny N. Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala-680651, India.
  • Usha N. Pillai Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala-680651, India.
  • Ajithkumar S. Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Pookode, Wayanad, Kerala-673576, India.
  • John Martin K. D. Department of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, Kerala-680651, India.
  • Shynu. M. Department of Veterinary Biochemistry, College of Veterinary and Animal Sciences, Pookode, Wayanad, Kerala-673576, India

Keywords:

Cardiac diseases, CvRDH, Microalbumin, Renal biomarkers, Serum inosine, Urine specific gravity

Abstract

Two types of cardiac disorders, viz Dilated cardiomyopathy (DCM) and acquired valvular disease, were diagnosed in dogs. Thirty non azotemic dogs with clinical signs suggestive of cardiovascular dysfunction formed part of this study. Standard treatment regimens as  required were administered during the study. Serum inosine, urine specific gravity, and microalbumin were the renal biomarkers evaluated  to diagnose these dogs' cardiovascular renal axis disorder subtype H (CvRDH). A decline in serum inosine values on day 45 as compared  to day 0 was suggestive of reduced renal functional status. Lowered urine-specific gravity in these non-azotemic dogs indicated renal  dysfunction. Urine microalbumin values documented were consistent with microalbuminuria,which proved to be a reliable biomarker  of glomerular damage and developing nephropathy. The renal biomarkers aided in the diagnosis of CvRDH in these dogs.  

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References

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Published

2022-09-19

How to Cite

Ghag, R.S., Unny N., M., Pillai, U.N., S., A., K. D., J.M., & M., S. (2022). Diagnosis of Cardiovascular Renal Axis Disorder Subtype Hin Non-azotemic dogs . Indian Journal of Veterinary Sciences and Biotechnology, 18(2), 105–108. Retrieved from https://acspublisher.com/journals/index.php/ijvsbt/article/view/2177