Ameliorating Effects of Mycotoxcease (Mycotoxin Binder) on Aflatoxin M1 Excretion in Dairy Cows
DOI:
https://doi.org/10.48165/ijvsbt.20.6.22Keywords:
AFM1 excretion, Crossbred cows, Economics, Feed intake and efficiency, Mycotoxin binderAbstract
This study was conducted on 16 crossbred cows to evaluate the effects of mycotoxcease on aflatoxin M1 excretion in milk, nutrient intake and feed efficiency. The cows were divided into two groups based on milk yield, days in milk and parity in T1 (Control) and T2 (Mycotoxcease). The total mixed ration-TMR was fed ad libitum to both groups in the morning and afternoon. The T2 cows were fed 50 g of toxin binder in equal halves after mixing with 500 g of concentrate and the same quantity without toxin binder was fed to T1 cows. The dry matter, crude fat, crude protein, and metabolizable energy intake were significantly lower in T2 group. The milk and milk component yield were not affected by toxin binder supplementation. The aflatoxin M1 excretion was 50% lower in T2 than T1 group. Bioconcentration and carry-over percentage were also effectively reduced in T2 group. The feed efficiency and cost of feeding were lower in T2 group. The supplementation of 50 g/day/cow toxin binder reduced aflatoxin M1 excretion, and nutrient intake, with improved feed conversion ratio and lower cost of feeding.
Downloads
References
AOAC (1995). Official Methods of Analysis, 16th end., Association of Official Analytical Chemists. Washington, D.C.
Aslam, N., Iqbal, Z.M., Warriach, H.M., & Wynn, P.C. (2014). Pattern of partitioning of aflatoxins from feed to urine and its effect on serum chemistry in Nili-Ravi buffalo heifers. Animal Production Science, 54(10), 1671-1675.
BIS (1981). Handbook of Food Analysis (XI), Dairy Products. Bureau of Indian Standards. Manek Bhavan, New Delhi, India, pp. 152-182. Campagnollo, F.B., Ganev, K.C., Khaneghah, A.M., Portela, J.B., Cruz, A.G., Granato, D., ... & Sant’Ana, A.S. (2016). The occurrence and effect of unit operations for dairy products processing on the fate of aflatoxin M1: A review. Food Control, 68, 310-329. Guo, W., Fan, Z., Fan, K., Meng, J., Nie, D., Tangni, E.K., ... & Han, Z. (2021). In vivo kinetics and biotransformation of aflatoxin B1 in
dairy cows based on the establishment of a reliable UHPLC-MS/ MS method. Frontiers in Chemistry, 9, 809480.
ICAR (2013). Indian Council of Agricultural Research, Nutrient Requirements of Animals-Cattle and Buffalo (ICAR-NIANP), New Delhi, India.
Jangam, A.K., & Wadekar, P.N. (2004). Web-based Agriculture Statistic software Package-WASP 2.0. Central Coastal Agricultural Research Institute, Indian Council of Agricultural Research, Goa, India.
Kuboka, M., Njue, L., Mutua, F., Grace, D., & Lindahl, J. (2022). AFM1 secretion and efficacy of NovasilTM clay in Kenyan dairy cows. Dairy, 3(2), 220-232.
Kutz, R.E., Sampson, J.D., Pompeu, L.B., Ledoux, D.R., Spain, J.N., Vazquez-Anon, M., & Rottinghaus, G.E. (2009). Efficacy of Solis, NovasilPlus, and MTB-100 to reduce aflatoxin M1 levels in milk of early to mid lactation dairy cows fed aflatoxin B1. Journal of Dairy Science, 92(8), 3959-3963.
Maki, C.R., Thomas, A.D., Elmore, S.E., Romoser, A.A., Harvey, R.B., Ramirez-Ramirez, H.A., & Phillips, T.D. (2016). Effects of calcium montmorillonite clay and aflatoxin exposure on dry matter intake, milk production, and milk composition. Journal of Dairy Science, 99(2), 1039-1046.
Masoero, F., Gallo, A., Diaz, D., Piva, G., & Moschini, M. (2009). Effects of the procedure of inclusion of a sequestering agent in the total mixed ration on proportional aflatoxin M1 excretion into milk of lactating dairy cows. Animal Feed Science and Technology, 150(1-2), 34-45.
Mehany, A.A., & Shams, A.S.E. (2019). Effect of toxin binder on productive performance of lactating Friesian cows. Journal of Animal and Poultry Production, 10(12), 405-413.
Ogunade, I.M., Arriola, K.G., Jiang, Y., Driver, J.P., Staples, C.R., &Adesogan, A.T. (2016). Effects of 3 sequestering agents on milk aflatoxin M1 concentration and the performance and immune status of dairy cows fed diets artificially contaminated with aflatoxin B1. Journal of Dairy Science, 99(8), 6263-6273.
Patel, S.B., Patel, B.B., & Patel, J.V. (2011). Effect of dietary supplementation of Mycofix® secure on milk production and its constituents in lactating crossbred cows. The Indian Journal of Field Veterinarians, 7(2), 15-19.
Queiroz, O.C.M., Han, J.H., Staples, C.R., &Adesogan, A.T. (2012). Effect of adding a mycotoxin-sequestering agent on milk aflatoxin M1 concentration and the performance and immune response of dairy cattle fed an aflatoxin B1-contaminated diet. Journal of Dairy Science, 95(10), 5901-5908.
Sarr, A.B., Mayura, K., Kubena, L.F., Harvey, R.B., & Phillips, T.D. (1995). Effects of phyllosilicate clay on the metabolic profile of aflatoxin B1 in Fischer-344 rats. Toxicology Letters, 75(1-3), 145-151.
Sherasia, P.L., Waghela, C.R., Sharma, R., Patel, A.P., Sridhar, V., Pawar, P.M., & Gupta, S.K. (2023). Effect of feeding bentonite clay on excretion of aflatoxin M1 in milk of dairy animals. Indian Journal of Animal Nutrition, 40(3), 296-304.
Snedecor, G.W., & Cochran, W G. (2014). Statistical Methods. 8th ed. The Iowa State University Press, Ames, Iowa, USA.
Sulzberger, S.A., Melnichenko, S., & Cardoso, F.C. (2017). Effects of clay after an aflatoxin challenge on aflatoxin clearance, milk production, and metabolism of Holstein cows. Journal of Dairy Science, 100(3), 1856-1869.
Sumantri, I., Murti, T.W., Van der Poel, A.F.B., Boehm, J., & Agus, A. (2012). Carry-over of aflatoxin B1-feed into aflatoxin M1-milk in dairy cows treated with natural sources of aflatoxin
and bentonite. Journal of the Indonesian Tropical Animal Agriculture, 37(4), 271-277.
Tolosa, J., Rodríguez-Carrasco, Y., Ruiz, M.J., & Vila-Donat, P. (2021). Multi-mycotoxin occurrence in feed, metabolism and carry over to animal-derived food products: A review. Food and Chemical Toxicology, 158, 112661.
Wakade, B.A., Ingole, S.D., Bharucha, S.V., & Nagvekar, A.S. (2019). Effect of toxin binders on immunity and aflatoxin M1 residues in milk in buffaloes. Indian Journal of Animal Science, 89, 944-950.
Xiong, J.L., Wang, Y.M., Nennich, T.D., Li, Y., & Liu, J. X. (2015). Transfer of dietary aflatoxin B1 to milk aflatoxin M1 and effect of inclusion of adsorbent in the diet of dairy cows. Journal of Dairy Science, 98, 2545-2554
Zentai, A., Jozwiak, A., Suth, M., & Farkas, Z. (2023). Carry-over of aflatoxin B1 from feed to cow milk - A review. Toxins, 15, 195. Zom, R.L.G., André, G., & Van Vuuren, A.M. (2012). Development of a model for the prediction of feed intake by dairy cows: 1. Prediction of feed intake. Livestock Science, 143(1), 43-57.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Indian Journal of Veterinary Sciences and Biotechnology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
How to Cite
