Biomarkers for Assessment of Fracture Healing in Dogs with Tibial Fracture

Authors

  • Ghulam Mehdi Department of Veterinary Surgery and Radiology, Veterinary College, Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • Bhagavantappa Department of Veterinary Surgery and Radiology, Veterinary College, Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • B Shivaprakash Department of Veterinary Surgery and Radiology, Veterinary College, Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • Dilip Kumar Department of Veterinary Surgery and Radiology, Veterinary College, Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • D Venkatgiri Department of Veterinary Surgery and Radiology, Veterinary College, Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • Vijay Kumar Department of Veterinary Pharmacology and Toxicology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • M Shweta S K Department of Veterinary Gynaecology and Obstetrics, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India

DOI:

https://doi.org/10.48165/ijvsbt.20.4.30

Keywords:

Alkaline phosphatase, Calcium, Biomarkers,, , Dog,, Fracture healing,, Phosphorus.

Abstract

The study was conducted in 12 clinical cases of dogs presented to the Department of Veterinary Surgery and Radiology in Bidar. They  were randomly divided into two groups consisting of 6 animals each. In group I fracture was repaired using interlocking nail (ILN) and  in group II with locking compression plate. The fracture healing was studied after the operation on day 0 (immediate), 15th, 30th and  60th. In both groups, calcium, phosphorus and alkaline phosphatase levels were estimated pre-operatively and on the above days for  assessment of fracture healing. The mean values of serum calcium and alkaline phosphatase gradually increased from the pre-operative  day reaching significantly the highest (p<0.05) level on the 15th post-operative day, after which the concentration gradually reduced till  the 60th post-operative day in both the groups. The increase in serum alkaline phosphatase was significantly higher at day 15th post operative in group I than in II, and all the values were within the physiological limit. 

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Published

2024-07-01

How to Cite

Mehdi, G., Bhagavantappa, Shivaprakash, B., Kumar, D., Venkatgiri, D., Kumar, V., & S K, M.S. (2024). Biomarkers for Assessment of Fracture Healing in Dogs with Tibial Fracture . Indian Journal of Veterinary Sciences and Biotechnology, 20(4), 143–145. https://doi.org/10.48165/ijvsbt.20.4.30