Studies on Haemato-Biochemical Findings in Hypothyroid Dogs
DOI:
https://doi.org/10.48165/ijvsbt.20.5.28Keywords:
hypothyroidism, thyroxine, hypercholesterolemia, hypertriglyceridemia, radioimmunoassayAbstract
Hypothyroidism is an endocrine disorder due to diminished synthesis and secretion of triiodothyronine (T3) and thyroxine (T4) by the thyroid glands. The present study was carried out at Veterinary Clinical Complex, NTR College of Veterinary Science, Gannavaram during the period from March 2023 to November 2023. The hospital prevalence of hypothyroidism in the present study was found to be 0.45 per cent (27/5957). The mean TT4 (7.74±0.60 nmol/L) and FT4 (0.32±0.04 ng/dL) in hypothyroid dogs was significantly (p ≤0.01) lower when compared to healthy dogs. Haemato-biochemical changes included significantly (P<0.01) reduced levels of haemoglobin (Hb), packed cell volume (PCV), and total erythrocyte count (TEC), along with elevated total leukocyte count (TLC), hypercholesterolemia, hypertriglyceridemia, and significantly (P<0.05) higher levels of alkaline phosphatase (ALP) and blood urea nitrogen (BUN). These findings emphasize the significant role of thyroid hormones in regulating the body's metabolic balance and ensuring the integrity of various organs.
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