Electrocardiographic Evaluation of Xylazine-Etomidate Isoflurane and Dexmedetomidine-Ketamine-Isoflurane  Anaesthesia under Guaifenesin Premedication for Various  Surgeries in Cattle

Authors

  • N M Ramya Department of Veterinary Surgery and Radiology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • B Bhagavantappa Department of Veterinary Surgery and Radiology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • Shivaprakash Department of Veterinary Surgery and Radiology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • D Dilip Kumar Department of Veterinary Surgery and Radiology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • Venkatgiri Department of Veterinary Surgery and Radiology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • M Vijay Kumar Department of Veterinary Pharmacology and Toxicology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India
  • Ghulam Mehdi Department of Veterinary Surgery and Radiology, Veterinary College Bidar-585401, Karnataka Veterinary Animal and Fisheries Sciences University, India

DOI:

https://doi.org/10.48165/ijvsbt.20.3.14

Keywords:

Cattle, Electrocardiography, Etomidate, Isoflurane, QRX complex

Abstract

The clinical study on electrocardiographic evaluationof two modalities of general anaesthesia was conducted in 12 clinical cases of cattle  of either sex. The animals were randomly divided into two groups, consisting of 6 animals in each group. The cattle in both groups were  premedicated with an intravenous injection of 50 mg/kg guaifenesin. The cattle in group-I were sedated with inj. xylazine (0.1 mg/kg  I/V) and induced with inj. etomidate (0.5 mg/kg I/V). The cattle in group-II were sedated with inj. dexmedetomidine (2.5 µg/kg I/V) and  induced with inj. ketamine (3 mg/kg I/V). Cattle from both groups were maintained under isoflurane anaesthesia. The morphological  abnormalities were not detected in electrocardiography in cattle of any of the groups, except for changes in the amplitude and duration  of the P wave, QRS complex, T wave, PR interval, and QT interval. 

Downloads

Download data is not yet available.

References

Abrahamsen, E.J. (2008). Ruminant field anaesthesia. Veterinary Clinics of North America: Food Animal Practice., 24(3), 429-441. Avdosko, G, Birgele, E., & Mencendorfa, L. (2010). Changes in electrocardiogramm of Cocker spaniel and German shepherd dogs during anaesthesia. Veterinary Medicine Zootechnics, 49, 8-16.

Bayan, H., Sarma, K.K., Rao, G.D., Dutta, D.K D., & Phukan, A. (2021). Cardiopulmonary functions in dogs under propofol, ketamine and isofluraneanaesthesiapremedicated with glycopyrrolate, dexmedetomidine and butorphanol. Indian Journal of Animal Research, 1, 1-6.

Cantalapiedra, A.G, Villanueva, B., & Pereira, J.L. (2000).Anaesthetic potency of isoflurane in cattle: Determination of the minimum alveolar concentration. Veterinary Anaesthesia and Analgesia, 27(1), 22-26.

Forman, S. A., & Warner, D.S. (2011). Clinical and molecular pharmacology of etomidate. Journal of American Society of Anesthesiologists, 114(3), 695-707.

Hall, L.W., Clarke, K.W., & Trim C.M. (2014). Veterinary Anaesthesia, 11th Edn., W.B. Saunders, China, pp. 147-162.

Ley, S., Waterman, A., & Livingston, A. (1990). Variation in the analgesic effects of xylazine in different breeds of sheep. Veterinary Record, 126, 508.

Lin, G.Y., Robben, J.H., Murrell, J.C., Aspegrén, J., McKusick, B.C., & Hellebrekers, L.J. (2008). Dexmedetomidine constant rate infusion for 24 hours during and after propofol or isoflurane anaesthesia in dogs. Veterinary Anaesthesia and Analgesia, 35(2), 141-153.

Liu, C., Lin, T., & Zhou, Z. (2018). Dexmedetomidine combined with etomidate or emulsified isoflurane for induction reduced cardiopulmonary response in dogs. PloS One, 13 (12), 0208625.

Pai, A., & Heining, M. (2007). Ketamine. Continuing Education in Anaesthesia, Critical Care and Pain, 7(2), 59-63.

Saini, R., Palecha, S., Tanwar, M., Bishnoi, P., Pooniya, R., & Palsania, S.K. (2020). Comparative efficacy of etomidate and propofol for anaesthesia in dogs. Indian Journal of Veterinary Surgery, 41(2), 92-97.

Sandhu, H., & Rampal, S. (2006). Essentials of Veterinary Pharmacology and Therapeutics, 2nd Edn., Kalyani Publishers, Delhi, India. pp. 218-219.

Sinner, B., & Graf, B.M. (2008). Ketamine. In: Modern Anesthetics. Handbook of Experimental Pharmacology. 2nd Edn., Edt. Schüttler, J. and Schwilden, H. Springer, Berlin, pp. 313-333.

Snedecor, G. W., & Cochran, W. G. (1994). Statistical Methods. 6th ed. Iowa State University Press, Ames, Iowa, USA.

Stepien, R.L., Bonagura, J.D., Bednarski, R.M., & Muir 3rd, W.W. (1995). Cardiorespiratory effects of acepromazine maleate and buprenorphine hydrochloride in clinically normal dogs. American Journal of Veterinary Research, 56(1), 78-84.

Tilley, L.P. (1985). Essentials of canine and feline electrocardiography: Interpretation and Treatment. 2nd edn., Lea &Febiger. Philadelphia, London, pp. 337-484.

Tweed, W.A., Minuck, M., & Nymin, D. (1972). Circulatory response to ketamine anaesthesia. Anesthesiology, 37, 613.

Gurukar, Vinutha K. (2016). Evaluation of dexmedetomidine and xylazine sedation for ketamine-isoflurane general anaesthesia in cattle undergoing clinical surgeries. Master Thesis. Karnataka Veterinary Animal and Fisheries Sciences University, Bidar, India.

Downloads

Published

2024-05-10

Issue

Vol. 20 No. 3 (2024): The Indian Journal of Veterinary Sciences and Biotechnology (IJVSBT) 2024

Section

Research Article

License

Copyright (c) 2024 Indian Journal of Veterinary Sciences and Biotechnology

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

Ramya , .N.M., Bhagavantappa, B., Shivaprakash, Kumar, D.D., Venkatgiri, Kumar, M.V., & Mehdi, G. (2024). Electrocardiographic Evaluation of Xylazine-Etomidate Isoflurane and Dexmedetomidine-Ketamine-Isoflurane  Anaesthesia under Guaifenesin Premedication for Various  Surgeries in Cattle. Indian Journal of Veterinary Sciences and Biotechnology, 20(3), 71–76. https://doi.org/10.48165/ijvsbt.20.3.14
Crossref
Scopus
Google Scholar
Europe PMC