Efficacy of PGF2α, Calcium, Phosphorus, Oxytetracycline and Meloxicam on Fetal Membrane Retention and Postpartum Ovarian Activity in Buffaloes

Sandeep  Indurkar; Rajendra Prasad  Tiwari; Girish Kumar  Mishra; Meenu  Dubey

doi:10.48165/ijar.2022.43.2.3

Authors

Sandeep Indurkar Department of Veterinary Gynacology and Obstetrics,College of Veterinary Science and Animal Husbandry, Anjora, Dau Shri Vasudev Chandrakar KamdhenuVishwavidyalaya, Durg- 491 001 (CG)
Rajendra Prasad Tiwari Department of Animal Nutrition College of Veterinary Science and Animal Husbandry, Anjora, Dau Shri Vasudev Chandrakar KamdhenuVishwavidyalaya, Durg- 491 001 (CG)
Girish Kumar Mishra Department of Veterinary Gynaecology and Obstetrics, College of Veterinary Sciences and Animal Husbandry, Rewa (Madhya Pradesh)
Meenu Dubey Department of Animal Nutrition College of Veterinary Science and Animal Husbandry, Anjora, Dau Shri Vasudev Chandrakar KamdhenuVishwavidyalaya, Durg- 491 001 (CG)

DOI:

https://doi.org/10.48165/ijar.2022.43.2.3

Keywords:

Buffalo, Postpartum, Prostaglandin analogue, Retention of placenta

Abstract

Present study was conducted on buffaloes (n=24) which were classified into two groups. In group I, 12 buffaloes after normal calving were randomly classified in treatment (n=6) and control (n=6) sub groups. Whereas in group II, 12 buffaloes after normal calving having RFM/ROP 12 hours after calving were randomly classified in treatment (n=6) and control (n=6) sub groups. In group I and II , the buffaloes in treatment group were administered Dinoprost (25 mg); Meloxicam @0.5 mg/kg body wt., Oxytetracycline @5 mg/kg body wt. i/m and calcium i/v immediately after and after 12 hours of calving, respectively. However, the buffaloes in control group were not given any treatment.There was lower incidence of RFM (16.66% vs 50.00%; P<0.05); early expulsion of fetal membranes (4.05±0.31 vs 4.66±0.99h; P>0.05), early disappearance of fetid discharge (1.83±0.10 vs 2.66±0.33 days; P>0.05), early disappearance of muco-purulent discharge (3.25±0.65 vs 4.66±0.61 days; P>0.05), early uterine involution (32.83±4.43 vs 36.00±6.91 days, P<0.05) and early resumption of ovarian activity (100.16±3.19 vs 109.83±6.34 days; P<0.05) in treatment than control group in the buffaloes of Group I. There was low incidence of RFM in treatment and control groups (00.00% vs 16.66%), early expulsion of fetal membrane (5.33±0.38 vs 8.3±0.86 h; P <0.05), early disappearance of fetid discharge (5.13±0.54 vs 7.16±0.95 days; P>0.05), early disappearance of muco-purulent discharge (5.00±0.52 vs 8.00±0.74 days; P<0.05), early uterine involution (34.00±0.62 vs 44.5±1.57 days; P <0.01) and early resumption of ovarian activity (103.66±2.09 vs 125.33±5.64 days, P<0.01) in treatment than control in the buffaloes of Group II with RFM 12 hours after calving. It could be concluded that immediate treatment regimen after calving reduces the incidence of retention of fetal membrane in buffaloes.

References

Archbald, L.F., Constant,S., Tran, T., Risco, C., Klapstein, E. and Elliot, J. (1994). Effect of sequential treatment with prostaglandin F2 alpha and/or oxytocin on estrus and pregnancy rate of lactating dairy cows. Theriogenology, 42,773-780.

Arthur, G.H. (1979). Retention of after birth in cattle.A review and commentary. Vet. Bull., 49, 5507.

Azawi, O.I., Rahawy, M.A. and Hadad, J.J. (2008).Bacterial isolates associated with dystocia and retained placenta in Iraqi buffaloes. Reprod. Domest. Anim., 43,286-292.

Barlund, C.S., Carruthers, T.D., Waldner, C.L. and Palmer, C.W. (2008).A comparison of diagnostic techniques for postpartum endometritis in dairy cattle. Theriogenology, 69(6),714-723.

Beagley, J.C., Whitman, K.J., Baptiste, K.E. and Scherzer, J.(2010).Physiology and treatment of retained fetal membranes in cattle. J. Vet. Intern. Med., 24,261-268.

Cui, D., Wang, S., Wang, L., Wang, H., Li, J.,Tuo, X., Huang, X. and Liu, Y.(2017). Treatment of the retained placenta in dairy cows: Comparison of a systematic antibiosis with an oral administered herbal powder based on traditional Chinese veterinary medicine. Livest. Sci., 196,55-60.

Darwash, A.O., Lamming, G.E. and Wooliams, J.A. (1997).The phenotypic association between the interval to post-partum ovulation and traditional measures of fertility in dairy cattle. Anim. Sci., 65(1), 9-16.

Drillich, M., Mahlstedt, M., Reichert, U., Tenhagen, B.A. and Heuieser, W. (2006). Strategies to improve the therapy of retained fetal membranes in dairy cows. J. Dairy Sci., 89,627-635.

El-Malky, O., Youssef, M., Abdel-Aziz, N. and Abd El-Salaam, A. (2010).Postpartum Performance Of Buffaloes treated With GnRH to overcome the impact of placenta retention. J. Am. Sci., 2,225-233.

Goff, J.P. (2006). Macromineral physiology and application to the feeding of the dairy cow for prevention of milk fever and other periparturient mineral disorders. Anim. Feed Sci. Technol., 126,237-257.

Han, I.K. and Kim, I.H. (2005).Risk factors for retained placenta and the effect of retained placenta on the occurrence of postpartum diseases and subsequent reproductive performance in dairy cows. J. Vet. Sci.,6,53-59.

Hendricks, K.E.M., Bartolome. J.A., Melendez. P., Risco.C. andArchbald, F. (2006).Effect of repeated administration of PGF2α in the early post partum period on the prevalence of clinical endometritis and probability of pregnancy at first insemination in lactating dairy cows. Theriogenology, 65,1454-1464.

Iqbal, S., Aleem, M. and Saeed, M.A.(2003). Role of single injection of PGF2α on breeding efficiency of postpartum buffalo. Pak. Vet. J., 22(1),32-36.

Jainudeen, M.R. and Hafez, E.S.E. (1993).Reproduction faliures in females. In Reproduction in Farm Animals. 6th Ed..Verghesc Co., Bombay, India, pp 261 -286.

Jha, S.S. (2011). Response of Prostaglandin F2 alpha in Buffalo. Asian J. Biochem. Pharma. Res., 1(3), 346-350.

Khar, S.K. (1980). Gynaecological problems of buffaloes in summer institute on buffalo management system, Haryana Agricultural University, Hisar.

Khatri, P.,Tunio, S.A., Kaka, I., Samo, M.U., Bhutto, B. and Memon, M.R. (2013).Effect of Exogenous PGF2α and Oxytocin on Postpartum Anestrus and Uterine Involution in KundhiBuffaloes. J. Anim. Prod. Adv., 3(4), 158-163.

Kunbhar, H.K. and IahMemon, A.U. (2011). Incidence of placental retention in Kundhi buffalo around Tandojam, Pakistan. Pak. J. Life Soc. Sci., 9, 21-23.

LeBlanc, S., Dufield, T., Leslie, K., Bateman, K., Keefe, G., Walton, J. and Johnson, W. (2002).The effect of treatment of clinical endometritis on reproductive performance in dairy cows. J. Dairy Sci., 85,2237-2249.

Maizon, D.O., Oltenacu, P.A., Grohn, Y.T., Strawderman, R.L. and Emanuelson, U. (2004).Effects of diseases on reproductive performance inSwedish Red and White dairy cattle. Prev. Vet. Med. 66,113-126.

Mavi, P.S., Pangaonkar, G.R., Sharma, R.K. and Gandotra,V.K.(2004). Effect of certain hormones on the reproductive performance of post-parturient buffaloes. Buffalo J. 20,193-201.

Muhammad, M.A. and Muhammad, D.K. (2002).Treatment of retained fetal membranes in cattle.National conference on factors limiting on dairy production in Pakistan.University of Agriculture, Faisalabad, Punjab, 8-9 April.

Mulligan, F., Grady, L.O., Rice, D. and Doherty, M.(2006). Production diseases of the transition cow: Milk fever and subclinical hypocalcemia. Ir.Vet. J., 59(12),697-702.

Nakao, T., Gamal, A.,Osawa, T., Nakada, K., Moriyoshi, M. and Kawata, K. (1997).Postpartum plasma PGF metabolite profile in cows with dystocia and/or retained placenta, and effect of fenprostalene on uterine involution and reproductive performance. J.Vet. Med. Sci.,59(9),791-94.

Patil, R.K., Sinha, S.N., Iinarsson, S. and Settergren, I. (1980). The effect of PGF2.alpha and oxytocin on bovine myometrium in vitro. Nord. Vet. Med., 32,474-479.

Pattabiraman, S.R. and Bawa,S.J.S. (1977). Incidence of pre and postpartum reproductive disorders in bovines. The Hariana Vet., 16,99-101.

Perumal, P., Chamuah, J.K., Krishanppa, B., Vupru, K. and Khate, K. (2013). Retention of placenta in mithun crossbred cow (Phre).A Case Report. Vet. World, 6(13),171.

Peter, A.R. and Laven, R.A. (1996). Bovine retained placenta aetiology pathogenasis and economic loss. Vet. Rec.,139,465-471.

Prakash, B.S. and Madan, M.L. (1985). Periparturient plasma progesterone and prostaglandin F (PGF) levels in buffaloes (Bubalus bubalis). Ind. J. Anim. Sci., 55,642-446.

Roberts, S.J. (1971). Veterinary Obstetrics and Genital diseases. 2ndEd.CBS Publishers and Distributers New Delhi, India, pp 208-211.

Roche, J.F. (2006). The effect of nutritional management of the dairy cow onreproductiveefficiency.Anim. Reprod. Sci., 96(3-4),282-296.

Roche, J.F., Mackey, D. and Diskin, M.D. (2000). Reproductive management of postpartum cows. Anim. Reprod. Sci., 60,703-712.

Seguin, B.E. (1981). Use of prostaglandin in cows with unobserved estrus. Acta Vet Scand Suppl. 77:343-52.

Shalaby, A.S., Sharawy, S.M., Saleh, N.H. and Hassan, E.A. (1994).Effect of PGF2α on the expulsion of the placenta and the interval from the birth to the first postpartum estrus in buffaloes. Assiut. Vet. Med. J., 31(61),320-326.

Sharma, R.D. (1976). Studies on retained placenta in buffaloes. Ph.D. Dissertation, Punjab Agricultural University Ludhiana, India.

Sheldon, I.M., Lewis.G.S., LeBlanc, S. and Gilbert, R.O.(2006).Defining postpartum uterine disease in cattle. Theriogenology, 65,1516-1530.

Singal, S.P. (1996).Efficacy of Exapar in post parturient disorders with retained placenta in bovines. Ind. J. Anim. Reprod., 17,109-110.

Singh, B., Nanda, A.S. and Arora, A.K. (1997). Comparative studies on postpartum uterine infections in dystocia affected cows and buffaloes. Ind. J. Anim.Sci.,67,477-479.

Singh, M. and Madan, M.L. (1985).Circulating PGF2a during estrous cycleamong buffaloes. Proceedings of the first World Buffalo Congress, Cairo Egypt, 8,569-571.

Singh, N., Chauhan, F.S. and Singh, M. (1979).Postpartum ovarian activity and fertility in buffaloes. Ind. J. Dairy Sci., 32,134-139.

Sinha, V.K., Singh, B. and Sinha, A.K. (2002). Management of postpartum reproduction in crossbreed cows with Dinoprost. Ind. J. Anim. Reprod., 23(1),21-24.

Thakur A, Ravikanth, K, Maini, S., Patil, A.D., Deshmukh, A.A. and Patil, A.D. (2013).Management of postparturient reproductive disorders in dairy animals with herbal uterine cleanser Exapar-N. Adv. Res. Pharma. Biol., 3,517-519.

Tiwari, R.P., Jogi, S. and Sahu, S.K. (2004). Effect of prostaglandin administration after calving in buffaloes on postpartum reproductive performance. Buffalo Bull., 23(3), 53-57.