Efficacy of Different Therapeutic Regimens in Subclinical Endometritis in Cross Bred Dairy Cows

Authors

  • Asloob Ahmad Malik Division of Animal Reproduction, Gynaecology and Obstetrics Shere-e-Kashmir University of Agricultural Sciences and Technology of Kashmir
  • Nahida Division of Animal Reproduction, Gynaecology and ObstetricsShere-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Srinagar, India-190006
  • Khursheed Division of Veterinary Clinical Complex Faculty of Veterinary Sciences and Animal Husbandry Shere-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Srinagar, India-190006
  • Mehrajuddin Division of Animal Reproduction, Gynaecology and Obstetrics Shere-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Srinagar, India-190006
  • Arjuma Division of Animal Reproduction, Gynaecology and ObstetricsShere-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama, Srinagar, India-190006

DOI:

https://doi.org/10.48165/ijar.2024.45.01.9

Keywords:

Cephapirin benzathine, Cross bred cows, Lugol’s Iodine, Repeat breedin, Subclinical endometritis

Abstract

The present study was conducted on cross bred cows (n=30) having completed 60 days postpartum to assess the efficacy of different treatments in subclinical endometritis in crossbred dairy cows. A total of 20 animals that tested positive for subclinical endometritis (SCE) on endometrial cytology and white side test were sub divided into three treatment groups corresponding to Group I-III. The Group IV consisting of 10 healthy animals without any uterine infection served as control in which AI was performed on day of estrus. In Group I, single intrauterine dose of cephapirin benzathine (500mg), Group II Levofloxacin @ 4-5 mg/kg bw i.m. and Group III Lugol’s Iodine (0.5%) @ 30ml I/U for 3 consecutive days were given, respectively. In first three groups, WST was conducted on subsequent estrus and animals testing negative were subjected to AI. Treatment efficiency was evaluated on the basis of first service conception rate. In Group I, Group II, Group III and Group IV first service conception rate was 50%, 40%, 33.33% and 60% respectively. FSCR was non significantly (P>0.05) higher in animals treated with cephapirin benzathine compared to other treatment groups. It was concluded that cephapirin benzathine is the most suitable treatment of SCE but Lugol’s Iodine can be recommended for treatment of SCE and improving conception rate.

References

Ahmed, F.O. and Elsheikh, A.S. (2014). Treatment of repeat breeding in dairy cows with Lugol’s iodine. IOSR J. Agri. and Vet. Sci., 7(4): 22-26

Asfar, A., Sofi, K.A., Fayaz, A., Bhat, M.A., Naikoo, M. and Rasool, S. (2020). Therapeutic evaluation of levofloxacin and Lugol’s iodine for subclinical endometritis. J. Anim. Res., 10(4): 623- 627.

Bhardwaz, A., Nema, S.P., Mahour, S.S., Bagati, S. and Kumar S. (2018). Therapeutic efficacy of Lugol’s iodine (I2 KI) in infectious repeat breeder crossbred cows. Int. J. Curr. Microbiol. Appl. Sci., 7: 648-654.

Carleton, C.L., Threlfall, W.R. and Schwarze, R.A. (2008). Iodine in milk and Serum following intrauterine infusion of Lugol’s solution. Inte. J. Appl. Res. Vet. Med., 6: 121–129.

Das, K.K. (2004). A trial on commonly available drugs and C’Flox (I.U) for the controlling of repeat breeding condi tion in cattle. Intas Polivet 5: 199-203.

Gilbert, R. O., Shin, S. T. Guard, C. L. Erb, H. N. and Frajblat, M. (2005). Prevalence of endometritis and its effects on reproductive performance of dairy cows. Theriogenology.,64:1879–1888.

Kasimanickam, R., Duffield, T.F., Foster, R.A., Gartley, C.J., Leslie, K.E., Walton, J.S. and Johnson, W.H. (2005). The effect of a single administration of cephapirin or clopros tenol on the reproductive performance of dairy cows with subclinical endometritis. Theriogenology., 63(3): 818-30.

Khalil, H.M., Waheeb, R. S., Abd El-Rheem, S. M. and El-Amrawi, G. A. (2023). Evaluation of Medical and Economical Efficacy of Some Protocols for Treatment of Postpartum Clinical Endometritis in Holstein Dairy Cows. Alex. J. Vet. Sci.,79(1): 150-157.

Kumar, S., Bhardwaz, A., Srivastava, A.K., Rao, M. and Kumar N. (2015). White side test- a field test on the cervical mucus of cows for diagnosis of endometritis. Intas Polivet., 16: 207- 214.

Nehru, D.A., Dhaliwal, G.S., Jan, M.H., Cheema, R.S. and Kumar, S. A. (2018). Clinical efficacy of intrauterine cephapirin benzathine administration on clearance of uterine bacte ria and subclinical endometritis in postpartum buffaloes. Reprod. Dom. Anim., 1-8.

Parikh, S.S. (2021). Comparative studies on different diagnostic methods and therapeutic approaches for postpartum sub clinical endometritis in Gir cows. Dissertation submitted to Kamdhenu University, Gandhinagar, Gujarat, India.

Parikh, S.S., Gajbhiye, P.U., Savaliya, K.B., Solanki, G.B. (2014). Effect of antibiotic treatment on pregnancy rate in repeat breeder Gir cows. Indian J. Field Vet., 10: 5-7.

Pillai, V.V. (2012). Efficacy of simultaneous use of enrofloxa cin and metronidazole in the treatment of endometritis in crossbred cattle-a field trial. J. Ind. Vet. Assoc., 10(2): 37-39.

Sarkar, P., Kumar, H., Rawat, M., Varshney, V.P., Goswami, T.K., Yadav, M.C. and Srivastava, S.K. (2006). Effect of adminis tration of garlic extract and PGF2 α on hormonal changes and recovery in endometritis cows. Asian Australas. J. Anim. Sci., 19: 964-969.

Sawale, A. G. and Markandeya, N. M. (2023). Efficacy of Ozone and Other Alternative Intrauterine Therapies in Infectious Repeat Breeder Cows. Indian J. Anim. Reprod., 44(2): 51–54.

Sheldon, I.M., Cronin, J., Goetze, L., Donofrio, G. and Schuberth, H.J. (2009). Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle. Biol. Rep., 81: 1025-1032.

Sheldon, I.M., Lewis, G.S., LeBlanc, S. and Gilbert, R.O. (2006). Defining postpartum uterine disease in cattle. Theriogenology., 65(8):1516-153030.

Singh, J., Honparkhe, M., Chandra, M., Kumar, A., Ghuman, S.P.S. and Dhindsa, S.S. (2016). Diagnostic efficacy of uter ine cytobrush technique for subclinical endometritis in crossbred dairy cattle. Ind. Vet. J., 93(02): 11–13.

Singh, M., Sharma, A., Kumar, P., Bhardwaj, N., Sharma, A. and Bala, I. (2018). Studies on clinical efficacy of some thera peutic regimens for the management of endometritis in cows. Explor Anim. Med. Res., 8(1): 110-112.

Snedecor, G. W. and Cochran, W. G. 1994. Statistical Method, 8th Edition. Iowa State University Press, Ames, USA. Sutriana, A., Sayuti, A., Panjaitan, B., Armansyah, T.R., Tunnisa, A.F., Melia, J., Siregar, T.N., Hafizuddin. and Aliza, D. (2021). The Effectiveness of Lugol on the Increasing of Pregnancy Rate in Aceh Cow with Endometritis. J. Agripet., 21 (2): 187-191.

Tomar, S.S., Sudershan., Bharadwaz, A., Nema, S.P. and Rajput, N. (2017). Phytotherapy has potential equivalent to anti biotic therapy for clearing the endometritis in crossbred cattle. Indian J. Anim. Reprod., 38 (2): 46-48.

Wagener, K., Gabler, C. and Drillich, M. (2017). A review of the ongoing discussion about definition, diagnosis and path mechanism of subclinical endometritis in dairy cows. Theriogenology., 94: 21-30.

Waheeb, R. and Hatab, S. (2017). Efficacy of administration of supplemental and Hormonal Therapies for Treatment of Postpartum True Anestrous Dairy Cows. Alex. J. Vet. Sci., 52(1): 103-108.

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Published

2024-04-30

Issue

Vol. 45 No. 1 (2024): The Indian Journal of Animal Reproduction( june)

Section

Research Article

How to Cite

Malik, .A.A., Yousuf, N., Sofi, K.A., Naikoo, M., & KHatun, A. (2024). Efficacy of Different Therapeutic Regimens in Subclinical Endometritis in Cross Bred Dairy Cows. The Indian Journal of Animal Reproduction, 45(1), 39–43. https://doi.org/10.48165/ijar.2024.45.01.9
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