Effect of Self Made Intravaginal Progesterone Sponge on Fertility in Goat
DOI:
https://doi.org/10.48165/ijar.2023.44.02.11Keywords:
Synchronization, Estrogen-progesterone, PMSG, Fertility, Fecundity and ProlificacyAbstract
Comparative studies of intravaginal sponges containing three different doses of progesterone on estrous synchronization; fertility, fecundity and prolificacy of synchronized does by natural mating were conducted during the breeding season at Central Sheep Breeding Farm, Hisar. A total of 60 Beetal does selected randomly and divided into group I, II and III with 20 does in each, and subsequently intravaginal sponges containing 50, 100 and 150 mg P4 were inserted respectively for 14 days and an i/m injection of PMSG (@200IU/doe) was injected just after sponge removal in each doe. Effective number of animals remained 55 as 5 does dropped their sponges. Forty eight to sixty hrs after sponge removal, 14, 16 and 15 does from group I, group II and group III respectively were synchronized to estrus and subsequently hand mated individually with bucks of proven fertility. The fertility, fecundity and prolificacy per cent after synchronization of oestrus in group I, group II and group III was 78.57, 87.50 and 86.66; 128.57, 156.25 and 166.66; 163.63, 178.57 and 192.30 respectively. Eighteen animals (6 does from each group) selected randomly out of 60 animals for progesterone estimation. Blood samples were collected immediately before insertion of intravaginal sponges (day 0) and then subsequently on day 7, 14 after sponge insertion and 48 and 72 hrs after sponge removal. Progesterone concentration was above basal level in most of animals on day 0 in all the groups. Increase in plasma progesterone concentration (with in group) was recorded on day 7 and decreased on day 14 & 48 hrs after sponge removal. These changes were significant in group II & III while non-significant in group I. Progesterone concentration decreased non-significantly 72 hours after sponge removal in all the three groups. Significant difference in plasma P4 concentration was reported in between group I and group II & III on day 7 & 14.
References
Ahmed, M.M.M., Makawi, S.E. and Jubara, A.S. (1998). Synchronization of oestrus in Nubian goats. Small Rumin. Res., 30: 113–120.
Alacam, E., Oszar, S., Klicoglu, C., Guven, B., Isgur, H., Tekele, T. and Glatrzel, P. (1985). Induction of estrus in Saanen goats at early breeding season by intravaginal progesterone sponges (MAP) or by prostaglandin F2α injections. Effect on different age groups. Theriogenology, 24(3): 283- 291
Banerjee, G.C. (2004). A textbook of Animal Husbandry. 8th edn. New Delhi: Oxford & IBH, :939
Baril, G., Leboeuf, B. and Saumande, J. (1993). Synchronization of estrus in goats: the relationship between time of occur rence of estrus and fertility following artificial insemina tion. Theriogenology,40:621–628.
Baril, G., Remy, B., Vallet, J.C. and Beckers, J.F. (1992). Effect of repeated use of progestagen-PMSG treatment for estrus control in dairy goats out of breeding season. Zuchthygiene (Berl.), 27:161- 168.
Becze, J. and Pappd, D. (1984). First result in developing a breed ing technique in goats. Hungary, ATX, 33-35.
Bongso, T.A., Fatimah, I and Dass, S. (1982). Synchronization of estrus of goats treated with progestagen impregnated intra vaginal sponges and PMSG, and reproductive performance following natural mating or A.I. with frozen semen. Anim. Reprod. Sci., 5(2):111-116.
Boscos, C.M., Samartzi, F.C., Dellis, S., Rogge, A., Stefanakis, A. and Krambovitis, E. (2002). Use of progestogen-go nadotropin treatment in oestrus synchronization of sheep. Theriogenology,58:1261-272.
Carlson, K.M., Pohl, H.A., Marcek, J.M., Muser, R.K. and Wheaton, J.E. (1989). Evaluation of progesterone con trolled internal drug release dispensers for synchronization of estrus in sheep. Anim. Reprod. Sci.,18:205-218.
Corteel, J.M., Leboeuf, B. and Baril, G. (1988). Artificial breeding of adult goats and kids induced with hormones to ovulate outside the breeding season. Small Rumin. Res., 1:19–35.
Das, G.K., Naqvi, S.M.K., Gulyani, R. and Mittal, J.P. (1998). Induction and synchronization of estrus in maiden ewes using Progesterone and PMSG during autumn season. Indian J. Anim.Mgmt.,69(10):797-798.
Das, G.K., Naqvi, S.M.K., Gulyani, R. and Mittal, J.P. (2001). Induction and synchronization of estrus in maiden ewes using progesterone and PMSG during autumn season. Indian J. Anim. Prod. Mgmt., 14(2):106-109.
Das, G.K., Naqvi, S.M.K., Gulyani, R., Anil, J., Pareek, S.R. and Mittal, J.P. (1999). Estrus synchronization response in Malpura ewes treated with PGF2α. Indian J. of Anim. Sci.,69(10):797-798.
Freitas, V.J.F., Baril, G. and Saumande, J. (1996). Induction and synchronization of estrus in goats: the relative efficiency of one versus two fluorogestone acetate impregnated vaginal sponges. Theriogenology,46: 1251–1256.
Fukui, Y., Ishikawa, D., Ishida, N., Okada, M., Itagaki, R., and Ogiso, T. (1999). Comparison of Fertility of Estrous Synchronized Ewes with Four Different Intravaginal Devices during the Breeding Season. Journal of Reproduction and Development, 45(5):337-343.
Godfrey, R.W., Gray, M.L. and Collins, J.R. (1997). A comparison of two methods of oestrous synchronisation of hair sheep in the tropics. Anim. Reprod. Sci., 47:99-106.
Gordon, I., (1971). Induction of early breeding in sheep by stan dard and modified progestagen PMSG treatment. J. Agric. Sci. (Camb.), 76: 337-342.
Górecki, M.T., Wójtowski, J., Kaczmarek, P., Danków, R., Sokolińsk, D. and Nowak, K.W. (2004) Concentrations of progesterone and 17β-estradiol in blood and milk and those of natural inhibitors in milk of goats in various phys
iological stages. Arch. Tierz., Dummerstorf, 47 (Special Issue): 90-96.
Hamra, A. H., McNally, J. W., Marcek, J. M., Carlson, K. M. and Wheaton. J.E. (1989). Comparison of progesterone sponges, cronolone sponges and controlled internal drug release dispensers on fertility in anestrous ewes. Anim. Reprod. Sci.,18:219-226.
Husein, M.Q. and Ababneh, M.M. (2007). A new strategy for superior reproductive performance of ewes bred out-of-sea son utilizing progestagen supplement prior to withdrawal of intravaginal pessaries. Theriogenology,69(3):376-83.
Kusina, N.T., Tarwirei, Hamudikuwanda, H., Agumba, G., and Mukwena, J. (2000). A comparison of the effects of pro gesterone sponges and ear implants, PGF2alpha, and their combination on efficacy of estrus synchronization and fer tility of Mashona goat does. Theriogenology, 53(8):1567- 1580.
Lamond, D.R. (1964). Synchronization of ovarian cycle in sheep and cattle. Anim. Breed. Abst., 32: 269-285.
Levy, T., Gurevitch, S., Bar-Hava, I., Ashkenazi, J., Magazanik, A., Homburg, R., Orvieto, R. and Ben-Rafael, Z. (1999). Pharmacokinetics of natural progesterone administered in the form of a vaginal tablet. Hum. Reprod., 14(3):606–610.
Menegatos, J., Chadio, S.E. Karatzas, G. and Stoforos. E. (1995). Progesterone levels throughout progestagen treatment influence the establishment of pregnancy in the goat. Theriogenology, 43:1365-1370.
Naderipour, H., Yadi, J., Shad A.G. and Sirjani, M.A. (2012). The effects of three methods of synchronization on estrus induction and hormonal profile in Kalkuhi ewes: A com parison study. Afr. J. Biotechnol., 11(5):530-533.
Nuti, L.C., Bretzlaff, K.N., Elmore, R.G., Meyers, S.A., Rugila, J.N., Brinsko, S.P., Blanchard, T.L. and Weston, P.G. (1992). Synchronization of estrus in dairy goats treated with pros taglandin F at various stages of the estrous cycle. Am. J. Vet. Res.,53:935-937.
Oh, Y.K., Suh, G.S., Kim, J.K., Sul, D.S., Kim, S.C., Lam, Y.B. and Kim, C.K. (1971). Effects of PMSG application on the ovar ian response and fecundity of goats. Livestock-Sericulture, 14(12):53-59.
Pathiraja, N., Oyedipe, E.O., Oyang, E.O. and Obasi, A. (1991). Plasma progesterone levels during oestrus cycle and their relationship with the ovulation rate in Red Sokoto (Maradi) goats. British Vet. J.,147:57-62.
Pierson, J.T., Baldassarre, H., Keefer, C.L. and Downey, B.R. (2001). Seasonal variation in preovulatory events asso ciated with synchronization of estrus in dwarf goats. Theriogenology, 56:759.
Ritar, A.J., Ball, P.D. and O’May, P.J. (1990) Artificial insemina tion of Cashmere goat: effects on fertility and fecundity of intravaginal treatment, method and time of insemination, semen freezing process, number of motile spermatozoa and age of females. Reprod. Fertil. Dev., 2:377– 384.
Ritar, A.J., Salamon, S., Ball, P.D. and O’May, P. J. (1989). Ovulation and fertility in goats after intravaginal device PMSG treatment. Small Rumin. Res., 2:323-331.
Robin, N, Laforest, J.P., Lussier, J.G. and Guilbault, L.A. (1994). Induction of estrus with intramuscular injections of GnRH or PMSG in lactating goats primed with a progestagen during seasonal anestrus. Theriogenology, 42(1):107-116.
Selvaraju, M., Kathiresan, D. and Devanathan, T.G. (2002). Oestrus synchronization in Malbari goats. Indian J. Anim. Sci., 73(4):410-411.
Souza, J.M.G., Torres, C.A.A., Maiab, A.L.R.S., Brandão, F.Z., Bruschi, J.H., Viana, J.H.M., Oba, E. and Fonseca, J.F. (2011). Autoclaved, previously used intravaginal proges terone devices induces estrus and ovulation in anestrous Toggenburg goats. Anim. Reprod. Sci., 129:50-55.
Waldron, D.F., Willingham, T.D., Thompson, P.V. and Bretzlaff, K.N. (1999). Effect of concomitant injection of prosta
glandin and PMSG on pregnancy rate and prolificacy of artificially inseminated Spanish goats synchronized with controlled internal drug release devices. Small Rumin. Res., 31:177-179.
Whiltley, N.C. and Jackson, D.J. (2004). An update on estrus synchronization in goats: A minor species. J. Anim. Sci., 82:270-276.
Wildeus, S. (2000). Current concepts in synchronization of estrus: Sheep and goats. J. Anim. Sci., 77:1- 14.
Downloads
Published
Issue
Section
How to Cite
