Seromycin, an Effective Treatment for Tuberculosis in Tamsk, Russia

Authors

  • Rishan Singh Research Media SR, Durban, 4001, South Africa & UKZN, South Africa & Association for Commonwealth Universities, UK

DOI:

https://doi.org/10.48165/

Keywords:

Seromycin, Tuberculosis, Sensitivity, Colonies, Russia

Abstract

This study was conducted to determine the minimum  inhibitory concentration of cycloserine on 6 isolates of  tuberculosis from Tomsk, Russia. Using the broth  microdilution (BM) method, the isolates were found to be  sensitive to 32 μg/ml of seromycin after 3 weeks of  treatment. These results conformed to the control strain,  irrespective of the amount of inoculum used. There was  an indirect relationship between the amount of culture  treated and the MIC of seromycin. All this show that  seromycin was an effective treatment for tuberculosis in  Tomsk, Russia.  

References

. Anon. (1965). Acute poisoning by cycloserine. Brit Med J. 1, 907- 908.

. Petrini B and Hoffner S. (1999). Drug resistant and multidrug resistant tubercle bacilli. Int J Antimicrobial Agents. 13, 93-97.

. Sharma SK and Mohan A. (2007). The implications of multidrug – resistant tuberculosis. Bact Infect. 52-54.

. Singh R. (2011). Mycobacterium tuberculosis: Telling a story of truths. J Pure Appl Microbiol. 5 (2), 541-544.

. Singh R. (2012). A biochemical and microbiological appraisal on the stability of the second-line anti-tuberculosis drug, cycloserine in Mycobacterium tuberculosis. J Pure Appl Microbiol. 6 (1), 209-211.

. Singh R. (2013). Minimum inhibitory concentration: Interpretation and cross-sectional analysis in an unstandardised 7H9 Mycobacterium tuberculosis

broth-based system – A hypothetical case. J Pure Appl Microbiol 7 (1), 777-784.

. Todar. (2011). Todar’s Textbook of Bacteriology: Tuberculosis. Madison Wisconson, USA. http://textbook/bacteriology.net/t

uberculosis.html. Accessed: 17 November 2011.

. WHO. (2012). A practical handbook on the pharmacovigilance of medicines used in the treatment of tuberculosis: enhancing the safety of the TB patient. Geneva Switzerland. WHO, Geneva, Switzerland.

. Zhang Y and Amzel LM. (2002). Tuberculosis drug targets. Curr Drug Targ 3, 131-151.

Published

2021-12-15

How to Cite

Seromycin, an Effective Treatment for Tuberculosis in Tamsk, Russia . (2021). Bio Science Research Bulletin, 37(2), 49–53. https://doi.org/10.48165/