Synthesis, Characterization, Antibacterial Studies of Co(II), Ni(II), Cu(II) and Zn(II) Complexes of Some Schiff Base Ligands

Authors

  • Abhishek Sharma Department of Chemistry Mewar University Gangrar, Chittorgarh, Rajasthan 312901, India
  • Sulekh Chandra Zakir Husain Delhi College (University of Delhi), JLN Marg, New Delhi 110002, India

DOI:

https://doi.org/10.48165/

Keywords:

Schiff Base, Ni(II), Co(II) and Cu(II) complexes, Spectroscopic Studies, DFT calculations, Antibacterial activity, antifungal activity

Abstract

A series of two biologically active Schiff base  ligands HL1 and HL2 have been synthesized in  equimolar reaction of acetophenone derivative  and different amines. The synthesized Schiff  bases were used for complexation with different  metal ions like Co(II), Ni(II) and Cu(II) by using a  molar ratio of ligand : metal as 1:1. The  characterization of Schiff bases and metal  complexes was done by 1H NMR, UV–Vis, IR,  Mass spectrometry and molar conductivity  studies. On the basis of the spectral studies an  octahedral geometry has been assigned for Co(II),  Ni(II) and tetrahedral for Cu(II) and Zn(II)  complexes. All the synthesized compounds were  studied for their in vitro antimicrobial activities,  against four bacterial strains and two fungal  strains by using serial dilution method. The data  also revealed that the metal complexes showed  better activity than the ligands due to  chelation/coordination. 

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Published

2019-06-20

Issue

Vol. 38 No. 1 (2019): Bulletin of Pure and Applied Sciences Zoology (Jan-Jun) 2019

Section

Articles

How to Cite

Synthesis, Characterization, Antibacterial Studies of Co(II), Ni(II), Cu(II) and Zn(II) Complexes of Some Schiff Base Ligands . (2019). Bulletin of Pure & Applied Sciences- Zoology , 38(1), 17–26. https://doi.org/10.48165/