Study of the Influence of Hypothyrous and Thyrotoxicosis on the Morphological Structure of the Spleen in Experimental Animals with Implanted Akatol Tumor

Authors

  • M A Ismayilova Associate Professor, Department of Physiology and Biochemistry of Humans and Animals, Samarkand State University, city, Samarkand, University Boulevard 15, Uzbekistan.

DOI:

https://doi.org/10.48165/

Keywords:

AKATOL, thyroid hormones, apoptosis, thyrotoxicosis, melanoma, proliferation of reticular tissue

Abstract

neoplasms is not only one of the most urgent in  medicine, but also affects many aspects of the social  life of society. The high rates of mortality from  malignant neoplasms and the associated significant  socio-economic losses make it possible to reasonably  consider the fight against malignant neoplasms as a  state problem. 

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References

Abduvaliev A.A. Ismayilova M.A., Gildieva M.S. & Saatov T.S. (2010). Elemental composition of bone tissue during the combined use of thyroxine and diazepam in a model carcinogenic system in mice // Problems of endocrinology. – Мoskow. №. 3. -pp. 31-33.

Abduvaliev A.A., Gildieva M.S. & Saatov T.S. (2006). Thyroxine regulation of the proliferation of estrogen- and progesterone-negative breast cancer cells. // Russian Journal of Oncology. Мoskow. № 2. - pp. 15-18.

Ismailov S.I. (2007). Elimination of iodine deficiency diseases in Uzbekistan. // Problems of Biology and Medicine. – Tashkent. № 4 (50). –pp.3-8.

Ipatov A.V. Invalidity of ailments of the endocrine system: camp, tendencies and medical and social problems // Endocrinology. № 2. - Р. 150-157

Karpova G.V., Timina E.A. & Karpova M.R. Method of morphological assessment of apoptosis for preclinical study of new drugs // Experimental and Clinical Pharmacology. – Moscow. № 6. - pp. 62-64.

Lakin G.F. (1990). Biometrics. M .: Higher mathematics.- pp.26-125.3. Abduvaliev A.A., Gildieva M.S. & Saatov T.S. (2005). Biological effects of thyroxine in experimental carcinogenesis. // Problems of endocrinology. Мoskow. №. 1. - pp.46-49. 4. Agol V.I. (1996). Genetically programmed cell death // Soros Educational Journal. - Moscow. № 6. - pp. 20-24.

Azimova B.Zh. (2008). Thyroxine regulation of apoptosis and proliferation of tumor cells in experimental carcinogenesis. - Dis. ... Cand. biol. sciences. - Tashkent, 2008 .- 120 p. 6. Akramova G.S., Umerov O.I. & Saatov T.S. (2002). Membrane lipids in the implementation of the effect of thyroxine on glucose transport in skeletal muscles // Uzbek Biological Journal. – Tashkent. №. 2. - pp.3-6.

Axel E.M. (2006). The state of cancer care to the population of Russia and the CIS countries in 2004 // Bulletin of the Russian Oncological Center. N.N.Blokhin RAMS. - Moscow. - №. 3 (17, app. 1). - pp.11-44.

Artykbaeva G.M. (1993). Investigation of the mechanism of regulation of thyroxine deiodination in target organs: Author's abstract. diss. ... Cand. biol. sciences. - Tashkent: IBKh AN RUz.-17 p.

Appay V., Sauce D., & Prelog M. (2010). The role of the thymus in immunosenescence: lessons from the study of thymectomized individuals. // Aging (Albany NY). - V.2 (2). - pp.78-81. 10. Babaeva A.G., Gevorkyan N.M. & Zotikov E.A. (2009) The role of lymphocytes in the operative change of the tissue development program. - Moscow: publishing house of the Russian Academy of Medical Sciences. 108 p.

Baryshnikov A.Yu. (2003). The relationship between the tumor and the body's immune system. // Practical Oncology. T.4. - № 3. - pp. 127-130.

Bazarov B.M., Rajamuradov Z.T. (2020). The total amount of leukocytes in the blood of astrakhan sheep and changes in the immune system depending on the seasons and nutritional conditions // International Journal of Advanced Science and Technology -Vol. 29, № 9s, - pp. 5327-5331.

Bueverov A.O., Tikhonina R.V., Moskaleva E.Yu., Popova O.N., Belushkina N.N., Severin S.E., Severin E.S., & Ivashkin V.T. (2000). Apoptosis of peripheral blood lymphocytes and granulocytes in chronic HBV and HCV infections // Russian Journal of Gastroenterology, Hepatology and Coloproctology. - Moscow. №. 6 (10). - pp. 33-36.

Vasiliev Yu.M. (1997). Social behavior of normal cells and antisocial behavior of tumor cells. I. Signaling molecules causing cell multiplication and death // Soros educational journal. – Moscow. № 4. - pp. 17-22.

Vasiliev Yu.M. (1997). Social behavior of normal cells and antisocial behavior of tumor cells. II. Cells build tissue // Soros Educational Journal. № 5. - pp. 20-25.

Volyansky A.Yu., Kuchma I.Yu., & Simirenko L.L. (2008). Infusion of exogenous thyroxine on the level of specific antigenesis for the minds of immunization with ADP-toxoid // Bulletin of Naukovikh Doslidzhen. №3. - pp. 69–71.

Granov A.M., Shutko A.N. (2002). The paradoxes of malignant growth and tissue incompatibility. - SPb: Hippocrates.- 224 p.

Ivchenko T.N., Zakharchenko O.P., & Stepanenko V.A. (2005). Comparative analysis of the effect of thyroxine on the rhythms of cell proliferation in normal and tumor tissues in vivo and in vitro. // Developmental Biology. №. 3. –

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Published

2020-11-15

Issue

Vol. 39 No. 2 (2020): Bulletin of Pure and Applied Sciences Zoology (Jul-Dec) 2020

Section

Research Paper

How to Cite

Study of the Influence of Hypothyrous and Thyrotoxicosis on the Morphological Structure of the Spleen in Experimental Animals with Implanted Akatol Tumor . (2020). Bulletin of Pure & Applied Sciences- Zoology , 39(2), 414–418. https://doi.org/10.48165/