Assessment of Genotoxicitxicity, Hepatotoxicity and Reproductive ctive of Imidacloprid on Mammammalian Models
DOI:
https://doi.org/10.48165/Keywords:
Neonicotinoid, Imidacloprid, Mammalian models, Hepatotoxicity, Reproductive toxicity, GenotoxicityAbstract
Imidacloprid, a systemic neonicotinoid neonicotinoid insecticide, isused widely to control various typesypes of harmful insects and pests to prevent crop damage. Use Use of imidacloprid was increased tremendously in last feww decades due to its lowtoxicityon mammals/vertebrates. tes. Consistent use of Imidacloprid in enormous amount showed howed evidences of toxicity in exposed non-target invertebravertebrates, vertebrates and also in mammals. This review focusfocuses on the extent of toxicity induced at genetic, biomolecular,biomolecular, biochemical and histological level due to exposure sure of imidacloprid on mammalian models. Various parameters like antioxidant enzyme assays, ccytotoxic assays, hematological parameters, histological cal parameters and reprotoxic assays are used to evaluate evaluate the toxicity of imidacloprid in mammalian models. . IImidacloprid may damage DNA, alter histology and distudisturb antioxidant system of the body. The outcome wiwill help in better understanding of imidacloprid toxiciticity on mammalian systems.
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