Unravelling the Complexity of SARS-CoV-2 and COVID-19: A Comprehensive Review

Authors

  • Aman Bhatia Research Scholar, Department of Zoology, Sardar Patel University, Mandi, Himachal Pradesh 175001, India
  • Gaurav Kapoor Assistant Professor, Department of Zoology, Sardar Patel University, Mandi, Himachal Pradesh 175001, India

DOI:

https://doi.org/10.48165/bpas.2023.42A.2.11

Keywords:

COVID-19, Cytokine storm, SARS-CoV-2, VOC (variant of concern), Hypercytokinaemia

Abstract

The recent pandemic of CoVID-19 was due to severe  acute respiratory syndrome 2 (SARS-CoV-2) and its  various viral variants and their evolutionled to a global  pandemic. SARS-CoV-2 is categorised under enveloped  viruses consisting of single stranded, non-segmented,  linear, positive sense strand RNA which functions as its  genetic material. Further sub categorised into five  important variants of concern namely, Alpha, Beta,  Gamma, Delta, and Omicron. Ribovirus interacts with  various receptors in human body most prominently  ACE2, APN, NEU-5, results in occurrence and  transmission. It is accompanied by induced  hypercytokinemia, also known as a cytokine storm.  Various cytokine and interlukins associated with it  results in acute respiratory distress syndrome (ARDS). This review contains a summarized account of recent  advancements regarding epidemiological, clinical and  pathological attributes of COVID-19 along with recent  progress in treatment and vaccine development. 

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Published

2023-12-20

Issue

Vol. 42 No. 2 (2023): Bulletin of Pure and Applied Sciences-Zoology (Jul-Dec) 2023

Section

Articles

How to Cite

Unravelling the Complexity of SARS-CoV-2 and COVID-19: A Comprehensive Review . (2023). Bulletin of Pure & Applied Sciences- Zoology , 42(2), 317–339. https://doi.org/10.48165/bpas.2023.42A.2.11