Phytochemistry and Gas Chromatography-Mass Spectrometry (GC MS) Analysis of Bioactive Components of Methanolic Root-Bark Extract of Boswellia dalzielii (Burseraceae)

Authors

  • U T Mamza Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria
  • M Rabiu Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria
  • S Khan Suny Downstate Health Sciences University, Department of Pediatrics Children’s Hospital New York, USA.
  • M Shah Parsons 10625 Rd, Johns Creek, GA 30097 Atlanta, USA.
  • M Arshad Study Hall, Vipul Khand, Gomti, Nagar, Lucknow, Uttar Pradesh 226010, India
  • J Yakubu Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria
  • S I Dawa Department of Chemistry, Borno State University, Maiduguri, Borno State, Nigeria
  • I Sule Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria
  • I Z Khan Department of Pure and Applied Chemistry, University of Maiduguri, Borno State, Nigeria

DOI:

https://doi.org/10.48165/

Keywords:

Phytochemistry, GC-MS Analysis, Bioactive compounds, Root-bark extract, Boswellia dalzielii

Abstract

This study was conducted to identify phytochemical constituents present in the methanolic root-bark  extract of B. dalzielii using GC-MS analysis and conventional phytochemical evaluation. The studies  revealed the presence of alkaloids, flavonoids, saponins, cardiac glycosides, terpenoids and  carbohydrates. A total of forty three compounds composed of eighteen major components were  identified thus; oxetane-2,3,4-trimethyl (3.45%), Bicyclo[4.1.0] heptan-3-one-7,7-dimethyl-4- methylene(IR) [2.69%], 2-methyl-2-(-2-oxopropyl) furan (3.20%), Cyclohexane, 2- (dimethylhydrazono)-3-[4-hexenyl]-1-acinitro,(E,) [2.63%], 3,8-Dihydroxy-3,4-dihydronaphthalen 1(2H)one (4.43%), 2-Tetradocanol (4.89%), 3-methyl-2-(2-oxopropyl)furan (3.46%), (2H)- Naphthalenenone, 6-(1,1-dimethyl ethyl) octahydro-2,8a-dimethyl (3.80%), Pentadecanoic acid  (6.18%), undecanoic acid (3.68%), Phthalic acid (4.14%), 1-Allyl-cyclohexane-1,2-diol (3.95%), 1,5,9- cyclotetradecatriene, 1,5,9-trimethyl-12-(1-methyl ethyl) [4.58%], 9,12-octadecadienoic acid (Z,Z)- methyl ester (4.75%). 9-octadecenoic acid, methyl ester[E] (4.36%), Tetradecanoic acid-methyl ester(S) [3.90%], (2S,4R)-p-mentha-[1(7),8]-diene-2-hydroperoxide (2.62%) and 1-Naphthalenepropanol, α ethyldecahydro-8a-(hydroxymethyl)-α, 5-dimethyl-2-methylene (2.93%). Most of the identified  compounds have been reported to possess various biological activities such as antimicrobial, anti inflammatory, antimalarial, antidiabetics, anti-asthmatic, anti-histamine, antitubercular, anti diarrhoeal among others. The studies thus concluded that B. dalzielii root-bark possesses potent  bioactive compounds and is recommended as a plant of phytopharmaceutical importance. The  presence of these bioactive compounds justifies the use of this plant in ethnomedicine. 

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References

Mamza, U. T., Yakubu, J., Chiroma, M., Balami, V. M., Moses, S., Sodipo, O. A., Abdulrahman, F. I., Alemika, T. E. and Khan, I. Z. (2021). Phytochemical Evaluation and In-vitro Antibacterial Properties of the Methanolic leaf Extract of Boswellia dalzielii Hutch. (Burseraceae). Bulletin of Pure Applied Science 40C Chemistry (2), 48-56.

Okezu, O. P., Mamza, U. T. and Adawara, S. N. (2020). GC-MS analysis of n-Hexane fruit peel extract of Persea americana (Laurceae). Tropical Journal of Natural Product Research .4(4), 146-152.

Mamza, U.T., Sodipo, O. A. and Khan, I.Z. (2012) Gas Chromatography-Mass Spectrometry (GC-MS) analysis of bioactive components of Phyllanthus amarus leaves. International Research Journal of Plant Science. 3(10), 208-215.

Yakubu, J., Mamza, U.T., Balami, V. M., Medugu, A. N., Abdulrahman, F.I. and Sodipo, O.A. (2020). Antidiabetic effects of partitioned methanol extract of Boswellia dalzieli (Frankincense tree) on rats. Journal of Phytopharmacology. 9(4), 224-229.

Mamza, U.T., Sodipo, O. A. A., Abdulrahman, F. I., Khan, I. Z (2018). Phytochemical analysis and in-vitro Antimicrobial Assay of the Methanol stem bark extract of Boswellia dalzielil Hutch (Burseralcal). Chemistry Reaserch Journal, 3(4), 161 - 168.

Ovedraogo A, Thiombiano A, Hahn Hadjali, K. and Guinko, S. (2006). Preliminary phytochemical and antispasmodic studies of Boswellia dalzielii Hutch. Medicinal plants in Burkina Faso. Journal of Applied Pharmaceutical Science, 8(9), 48-54.

Arbonnier, M. (2000). Arbres, arbustes et lianes des zones seches d’Afrique de l’Ouest. Cirad/MnhnUicn, Montpellier: CIRAD, MNHN; p. 541.

Danlami, U., Daniel., G. J., David, B. M. and Galadanchi, K. M. (2015). Phytochemical, nutritional and antimicrobial screening of hexane, ethyl acetate and ethanolic extracts of Boswellia Dalzielii leaves and bark. American Journal of Biological science and Biological Engineering. 3(5), 76-79.

Burkill, H. M. (1985).Useful Plants of West Tropical Africa. Volume one, Royal Botanical Gardens Kew, 300p.

Shinkafi TS, Bello L, Hassan SW, Ali S (2015). An ethnobotanical survey of antidiabetic plants used by Hausa–Fulani tribes in Sokoto, Northwest Nigeria.

Journal of Ethnopharmacology. 172:91–99. 12. Mamza, U. T., Madziga, A. M., Yakubu, J., Sodipo, O. A., Abdulrahman, F. I. and Khan, I. Z. (2020). Qualitative phytochemical evaluation and Antispasmodic studies of the stem-bark of Boswellia dalzielii on rabbit jejunum. International Journal of Academic Research and Development, 5(2), 45-49.

Singariya, P., Mourya, K. K. and Kumar, P. (2015). Gas Chromatography-Mass Spectrometric analysis of acetone extract of Marwar Dhaman grass for Bioactive compounds. Plant Achive, 15(2), 1065-1074.

Brain, K.R. and Turner, T.D. (1975). Practical evaluation of phytopharmaceuticals. Wright-Scientechnica. 1st Ed. Bristol; p.144.

Evans, W.C. (2009). Trease and Evans Pharmacognosy, 15th Ed. Harcourt Publishers Ltd. China, 585 pp.

Markham, R. (1982). Support from flavonoid glycoside distribution for the division of Dacrydiumsensulato. Newzealand Journal of Botany, 8(2), 1175- 8643.

Vishoni, S. (1979). Advanced practical organic chemistry. Journal of Organic Chemistry,4(2), 622-642.

Silver, p., John, G. and Mason, F. (1998): Phytochemical Method, A Guide to Modern Techniques of Plant Analysis 1st Edition, Chapmen and Hall London, ISBN: 04/2572605 pp. 15.

Sofowora, A., (2008). Medicinal Plants and Traditional Medicine in Africa. Spectrum books Ltd. Ibadan, Nigeria. p. 289.

Okezu, O. P., Mamza, U. T. and Adawara, S. N. (2020). GC-MS analysis of n-Hexane fruit peel extract of Persea americana (Lauraceae). Tropical Journal of Natural Product Research, 4(4), 146-152.

Ariharan, V.N., Kalirajan, K. and Mahendra, P. (2015). Gas Chromatography-mass Spectrometry determination of bioactive components of three traits of vilvam (Bael). Asian Journal of Pharmaceutical and Clinical Research,8(2), 49-61.

Hussein, J.H., Imad, H.H. and Muhammed, Y. H. (2017). Using gas chromatography mass spectrometry (GC MS) technique for analysis of bioactive components of methanolic leaves extract of Lopodium sativum. Research Journal of Pharmaceutical Science and Technology, 10(11), 3981-3989.

Mohammed, S. K., Samina, K. Y., Lim, P. K. and Muhammad, D. S. (2016). Chemical composition and antioxidant activity of essential oil of leaves and flowers of Alternanthera sessilis red from Sabah. Journal of Applied Pharmaceutical Science, 6(12), 157-161.

Khan, M.S., Yusufzai, S.K., Kaun, L.P. and Shah, M.D. (2016). Chemical composition and antioxidant activity of essential oil of leaves and flowers of Alternanthera sessilis red from Sabah. Journal of Applied Pharmaceutical Science, 6(12), 157-161.

Sarah, F.A., Nepal, I.A. and Arjun, B. (2020). Phytochemical profile and anti fungal activity of stems and leaves methanol extract from the Juncus maritimus Linn. Juncaceae family against some dermatophyte fungi. The 8th International Conference on Applied Science and Technology, 12(393), 287-292.

Saikarthik, J., Ilango, S., Vijayakumar, J. and Vijayaraghavan, R. (2017). Phytochemical analysis of methanolic extract of seeds of mucuna pruriens by gas chromatography mass spectrometry. International Journal Pharmaceutical Sciences and Research, 8(7), 2916-2921.

Shaheed, A., Abdul, K., Imtair, N. (2019). Analysis of bioactive phytochemical compound of cyperusiria L. by using gas chromatography- mass spectrometry. International Conference on Agricultural Science, 3(12), 324-331.

Manas, M. and Raka, K. (2011). Studies on trigonelline from Moringa oleifera and it's in- vitro regulation by feeding precursor in celi cultures. Brazilian Journal of Pharmacognosy, 8(2), 398-426.

Pawan, K., Sukhbir, L., Rang, A.C. and Dhirender, K. (2014). GC-MS analysis of bioactive constituents of Pinus roxburghiis arg (pinaceae) from northern India. Research Journal of Phytochemistry, 8(2), 42- 46.

Jenan, M. U., Mohammed, Y. H. and Imad, H.H. (2017). Bioactive chemical compounds identified on methanolic extract of Trogoderma granarium. Research Journal of Pharmaceutical Science and Technology, 10(11), 347-352.

Yuvaraj, R., Mudiganti, R.K., Prablu, K. (2019). The gas chromatography mass spectrometry study of one medicinal plant Stachytarpheta indica. Indian Journal of Pharmaceutical Science, 12(8), 382-394.

Okereke, S.C., Ijeh, I.I. and Arunsi, U.O. (2017). Determination of bioactive constituents of Ranwolfia vomitoria afzel roots using gas chromatography-mass spectrometry (GC-MS) and Fourier transform infrared spectrometry (FT-IR). African Journal of Pharmacy and Pharmacology, 11(2), 25-31.

Grace, O., Koliwole, I.A. and Cajethan, O.E. (2020). GC-MS analysis of bioactive compounds and evaluation of antimicrobial activity of the extracts of Daedalea elegans: A Nigerian mushroom. African Journal of Microbiology Research, 14(6), 204-210.

Anthonia, O. and MacDonald, J. (2017). GC-MS analysis of ethanolic extract of

Boswellia dalzielii (Burseraceae) root from Nigeria. Chemistry Research Journal, 2(2), 33-38.

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Published

2022-06-12

Issue

Vol. 41 No. 1 (2022): Bulletin of Pure and Applied Sciences-Chemistry (Jan-Jun) 2022

Section

Articles

How to Cite

Phytochemistry and Gas Chromatography-Mass Spectrometry (GC MS) Analysis of Bioactive Components of Methanolic Root-Bark Extract of Boswellia dalzielii (Burseraceae) . (2022). Bulletin of Pure and Applied Sciences-Chemistry , 41(1), 9–21. https://doi.org/10.48165/