The Role of Medicinal Plants in Domestic Animals and Estrus Induction with Particular Reference to Aegle marmelos and Murraya Koenigii

Anju  Kujur; N.  Srivastava; Nancy  Jasrotia; Arunpandian  J

doi:10.48165/aru.2022.2102

Authors

Anju Kujur Division of Animal reproduction, ICAR-Indian Veterinary Research Institute, Bareilly-243122, Uttar Pradesh, India
N. Srivastava Division of Animal reproduction, ICAR-Indian Veterinary Research Institute, Bareilly-243122, Uttar Pradesh, India
Nancy Jasrotia Division of Animal reproduction, ICAR-Indian Veterinary Research Institute, Bareilly-243122, Uttar Pradesh, India
Arunpandian J Division of Animal reproduction, ICAR-Indian Veterinary Research Institute, Bareilly-243122, Uttar Pradesh, India

DOI:

https://doi.org/10.48165/aru.2022.2102

Keywords:

Anestrus, Herbal plants, Murraya koenigii, Aegle marmelos

Abstract

Due to malnutrition and inadequate management practices, anestrus is frequently observed in domestic animal species, particularly in rural areas. This financially crippling condition in affected animals can be mitigated using available therapeutic measures. The primary challenges with employing hormones or other medicaments for animal reproductive management are the massive price, lack of rapid assay resources, barely commercially accessible and the requirement for veterinarian care. Therefore, herbal medicines are a good alternative since they are cheap, effective, and socially acceptable and they are often the only option with little side effects. Herbal combinations can have significant beneficial effects due to the synergistic or cumulative effects of their active principles. Plants have a wide spectrum of beneficial effects in their natural state and have immense potential as a source of new medications. Traditional remedies Murraya koenigii (curry leaves) and Aegle marmelos (bael) have been shown to boost reproductive performance in lab rats, anoestrus caprine and bovines.

References

Ahmed BM. Effect of fenugreek (Trigonella foenumgraecum) seeds as feed additive on production performance of dairy goats. PhD thesis submitted to NDRI, Karnal, 2009.

Arun A, Patel OPS, Saini D, Yadav PP, Konwar R. Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis. Biomed Pharmacother. 2017 Sep;93:510-521. doi: 10.1016/j.biopha.2017.06.065.

Balasundaram T. Treating infertility. Honey Bee. 1998; 9(3):9.

Bechardas PK. Imparting puberty. Honey Bee.1992; 3(2):22.

Berhane M. Studies on feeding some indigenous galactopoeitic feed supplements on milk production in crossbred cows. MSc Thesis submitted to JNKVV, Jabalpur, 2000.

Bhandari PR. Curry leaf (Murraya koenigii) or Cure leaf: Review of its curative properties. J Med Nutr Nutraceut. 2012;1:92-7.

Bonde SD, Nemade LS, Patel MR, Patel AA. Murrayakoenigii (Curry leaf): Ethnobotany, phytochemistry and pharmacology - A review. Int J Pharm Phytopharmacol Res. 2011;1: 23-7.

Chander M, Mukharjee R. Traditional agriculture and animal husbandry practices for sustainable agriculture in Kumoun hills of Uttar Pradesh. J Rural Dev (NIRD). 1994; 13(3):443-449.

Das GK, Mehrotra S, Narayanan K, Kumawat BL, Dey UK, Khan TA. Oestrus induction response and fertility performance in delayed pubertal heifers treated with A. marmelos and M. koenigii. J Anim Res. 2016; 6 (1): 921-926.

Das P, Biswas S, Ghosh TK, Haldar S. Micro-nutrient status of dairy cattle in new alluvial zone of West Bengal. Ind J Anim Sci. 2002; 72(2): 171-173.

Dutt R, Mehrotra S, Hoque M, Shanker U, Singh G, Agarwal SK, Das GK, Singh SK. Effect of M. koenigii and A. marmelos combination on resumption of fertility in anestrous goats. J Appl Anim Res. 2010; 38: 275-278.

Dutt R, Mehrotra S, Shanker U, Singh G. Effect of M. koenigii and A. marmelos feeding on anoestrus buffaloes. Ind J Anim Reprod. 2011;32 (1): 47-49

Dutt R, Mehrotra S, Singh G, Shankar U. Serum tri-iodothyronine and thyroxine profile in M. koenigii and A. marmelos combination treated acyclic goats. Haryana Veterinarian. 2012; 55: 53-55.

Gupta SL. Traditional agriculture knowledge and its rationality in Khawar community of Varanasi Dt. (UP). PhD thesis submitted to Banaras Hindu University, Varanasi, 1993.

Hegde GV, Nimbalka GS, Hegde GS, Naik K. Use of herbal plants for repeat breeding problem in dairy animals. Ind Vet J. 2002; 79: 861- 862.

Iman V, Mohan S, Abdelwahab SI, Karimian H, Nordin N, Fadaeinasab M, Noordin MI, Noor SM. Anticancer and anti‐inflammatory activities of girinimbine isolated from Murrayakoenigii. Drug Des Dev Ther. 2017; 103–121.

Janarthanan UK, Varadharajan V, Krishnamurthy V. Phytonutrients in Aegle Marmelos (L.) Leaves. World J Pharmacy Pharmaeut Sci. 2012; 1: 799-809.

Jayakumar S. Effect of certain medicinal plants on ovarian function in experimental animal. MVSc thesis submitted to Indian Veterinary Research Institute, Izatnagar, U.P., India, 1997.

Jondhale NS, Mehrotra S, Agarwal SK, Singh SK, Das GK, Kumar D, Shanker U, Deori, S. Effect of A. marmelos and Ficus religiosa leaves extracts on the ovarian function in rats. Ind Vet J. 2009; 86(4):353-355.

Jondhale NS. Effect of A. marmelos and Ficus religiosa on the ovarian function in rats and follicular dynamics in goat. MVSc Thesis submitted to Indian Veterinary Research Institute, Izatnagar, Bareilly, India, 2007.

Kabir KK, Rawal CVS, Ansari MR, Varshney JP, Srivastava RS. Comparative efficacy of herbal preparation in the management of anestrus in no descript rural buffaloes. Ind J Anim Reprod. 2001; 22(2) :143-145.

Kabir KK, Varshney JP, Rawal CVS, Srivastava RS, Ansari MR. Comparative efficacy of herbal preparations in the management of anoestrus in non escriptive rural buffaloes. Ind J Anim Reprod. 2001; 22:143-145.

Khade NB, Patel DM, Naikoo M, Dhami AJ, Sarvaiya NP, Gohel MM. Estrus induction in pubertal anestrus Gir heifers using different hormone protocols. Ind J Field Vet. 2011; 7:4 21-23.

Kumar B, Sachan V, Kumar A, Singh V, Das GK, Saxena A. Effect of Supplementation of A. marmelos and M. koenigii on the follicular development in delayed pubertal Sahiwal heifers. J Anim Res. 2016; 6(6): 1047-1052.

Kumar S, Mehla RK, Gupta AK, Meena RK. Influence of Asparagus racemosus (Shatavari) supplementation during different stage of lactation on estrus behavior and reproductive performance in Karan Fries crossbred cows. Livestock Res Rural Dev. 2010; 22(5).

Kumar S, Punniamurthy N. Estrus induction by supplementation of Murrayakoenigii in anestrus heifers. Ind J Anim Reprod. 2009; 30(2).

Kumar, R. Effect of A. marmelos (Bel) and Ficus religiosa (Pipal) on the reproductive performance in anoestrus goat and buffalo. MVSc Thesis submitted to Indian Veterinary Research Institute, Izatnagar, India, 2008.

Kumawat BL, Das GK, Narayanan K, Mehrotra S, Prasad JK, Ghosh SK, Kumar H. Effect of A. marmelos and M. koenigii on oestrus induction, conception and calving rate in delayed pubertal heifers under field condition. Ind J Anim Reprod. 2016; 37 (2): 17-19.

Mehrotra S. Studies on ovarian function using certain medicinal plants in rats, goat and cattle. PhD Thesis submitted to Indian Veterinary Research Institute, Izatnagar, Bareilly. India, 2002.

Mishra BP, Nayak N, Mishra D. Indigenous methods for animal health care. International seminar on traditional knowledge, health and environment, held during 23–24 February 2002, at Bhubaneshwar, Abs, pp. 124 National symposium and XXVII Annual convention of ISSAR, of Murrayakoenigii and Aegle marmelos in delayed pubertal heifers.2002.

Morabad BR, Kerur BR, Lagare MT, Anilkumar S. Heavy metal content in some therapeutically important medicinal plants. Analyt Chem Int J Anim Reprod. 2009; 30: 66-67.

Nalli Y, Khajuria V, Gupta S, Arora P, Riyaz‐Ul‐Hassan S, Ahmed Z, AliA. Four new carbazole alkaloids from Murrayakoenigii that display anti‐inflammatory and anti‐microbial activities. Org Biomol Chem. 2016; 14, 3322–3332.

Nandini MST, Veena T, Swamy MS. Effect of extracts of M. koenigii Spreng and Morus albalinn on the age of attainment of puberty and ovarian folliculogenesis in rats. J Basic Clinical Pharmacy. 2010; 1 (4): 203-207.

Ngeh J Toyang, MopoiNuwanyakpa, Chritopher Ndi, Sali Django, Wirmum C Kinyuy. Ethnoveterinary medicine practices in the Northwest Province of Cameroon. Indigenous Knowledge and Development Monitor, 1995.

Pandey SK, Sahay A, Pandey RS, Tripathi YB. Effect of Asparagus racemosus rhizome (shatavari) on mammary gland and genital organs of pregnant rat. Phytotherapy Research. 2005; 19(8):721-724.

Pandit RK. Incidence of different kinds of reproductive disorders in livestock performance in delayed pubertal heifers treated with Aegle marmelos preparations in the management of anestrus in nondescript ruralproblems in dairy animals. Ind J Anim Reprod. 2004; 25: 35-36.

Parmar HD. To bring animal to heat. Honey Bee. 1998; 9(3):17.

Patel KP, SahuJ, SahuL, Dubey BK. Aegal Marmelos: A Review on its Medicinal plants. Int J Pharm Phytopharmacol Res. 2012;1(5):332-341.

Perumal P, Veeraselvam M, Nahak AK. Herbal treatment in animal reproduction. Inter J Bioresource Stress Management 2013; 4(3):460-467.

Priyadarshini CH, Prasad PS, Kumar KA, Raj Solomon, Nagalakshmi D, Madhuri D. Ameliorative effect of Saracaasoca leaves on postpartum anoestrum Murrah buffaloes. The Pharma Inn J. 2021; 10(7): 568-570.

Rajkumar R, Srivastava SK, Varshney VP, Mahmood S. Effect of medicinal plants Saracaasoca and Trigonella foenum- graecum in anoestrus cows. Ind Vet J. 2008; 85:1281-1283.

Ranjan S, Sethuraman M. Traditional practices in rural areas of Dindigul district, Tamilnadu, India. Indigenous knowledge and development monitor. 1997; 5(3):709.

Rautela R, Das GK, KhanFA, Prasad S, Kumar A, Prasad JK, Ghosh SK, Dhanze H, Katiyar, R, Srivastava SK. Antibacterial, anti-inflammatory and antioxidant effects of A. marmelos and M. koenigii in dairy cows with endometritis. Livestock Sci. 2018; 214:142-148.

Sathesh Kumar S, Punniamurthy N. Effect of M. koenigii (Curry leaves) supplementation on oestrus induction and serum calcium and phosphorus concentrations of anoestrus heifers (Abstract), XXI Annual Convention of ISSAR and National Symposium on: Recent Trends and Innovations in Animal Reproduction: Nov. 23rd – 25th, 2005;SKAUST, Jammu. p.p. 100.

Sharma S, Handu S, Dubey A, Sharma P, Mediratta P, Ahmed Q. Anti‐anxiety and anti‐depressant like effects of Murrayakoenigii in experimental models of anxiety and depression. Anc Sci Life. 2017; 36, 215–219.

Singh S, Sidhu SS, Verma HK. Incidence of reproductive disorders in different zones of Punjab state. J Res (Punjab Agricultural University), 2003.

Sudarsanam G, Reddy MB, Nagaraju N. Veterinary crude drugs in Rayalaseema, A.P., India, Int J Pharmacognosy. 2008; 33(1): 52-60.

Syiem D, Sharma R, Saio V. In vitro study of the antioxidant potential of some traditionally used medicinal plants of North-East India and assessment of their total phenolic content. Pharmacologyonline. 2009;3:952–965.

Tomar KS. Effect of feeding indigenous feed supplements on productive and reproductive performance of dairy animals. MV Sc Thesis submitted to JNKVV, Jabalpur, 1995.

Tripathi Y, Anjum N, Rana. A Chemical composition and in vitro antifungal and antioxidant activities of essential oil from Murrayakoenigii (L.) Spreng Leaves. Asian J Biomed Pharm Sci. 2018; 8, 6–13.

Umashanker, Agarwal, Mehrotra SK, Singh SK, Hoque M. Restoration of fertility in anoestrus buffaloes using M. koenigii (Curry leaf plant). XXII Annual Convention and National Symposium on Innovative Technologies for Fertility Enhancement in Livestock, Nov.2006; 10-12, MHOW (M.P) PP-28, pp. 283.

Xin Q, Muer A. Girinimbine inhibits the proliferation of human ovarian cancer cells in vitro via the phosphatidylinositol‐3‐kinase (PI3K)/akt and the mammalian target of rapamycin (mTOR) and Wnt/β‐ catenin signalling pathways. Med Sci Monit. 2018; 24: 5480–5487.